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SNO-EANO-EURACAN consensus on management of pineal parenchymal tumors

Pineal parenchymal tumors are rare neoplasms for which evidence-based treatment recommendations are lacking. These tumors vary in biology, clinical characteristics, and prognosis, requiring treatment that ranges from surgical resection alone to intensive multimodal antineoplastic therapy. Recently,...

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Main Authors: Liu, Anthony P.Y. (Author) , Li, Bryan K (Author) , Vasiljevic, Alexandre (Author) , Dewan, Michael C (Author) , Tamrazi, Benita (Author) , Ertl-Wagner, Birgit (Author) , Hansford, Jordan R (Author) , Pfaff, Elke (Author) , Mynarek, Martin (Author) , Ng, Ho-Keung (Author) , Tsang, Derek S (Author) , Gottardo, Nicholas G (Author) , Gajjar, Amar (Author) , Bouffet, Eric (Author) , Dufour, Christelle (Author) , Pizer, Barry (Author) , Schiff, David (Author) , Jenkinson, Michael D (Author) , Lombardi, Giuseppe (Author) , Wen, Patrick Y (Author) , van den Bent, Martin J (Author) , Huang, Annie (Author)
Format: Article (Journal)
Language:English
Published: December 2024
In: Neuro-Oncology
Year: 2024, Volume: 26, Issue: 12, Pages: 2159-2173
ISSN:1523-5866
DOI:10.1093/neuonc/noae128
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/neuonc/noae128
Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/neuro-oncology/article/26/12/2159/7723335
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Author Notes:Anthony P.Y. Liu, Bryan K. Li, Alexandre Vasiljevic, Michael C. Dewan, Benita Tamrazi, Birgit Ertl-Wagner, Jordan R. Hansford, Elke Pfaff, Martin Mynarek, Ho-Keung Ng, Derek S. Tsang, Nicholas G. Gottardo, Amar Gajjar, Eric Bouffet, Christelle Dufour, Barry Pizer, David Schiff, Michael D. Jenkinson, Giuseppe Lombardi, Patrick Y. Wen, Martin J. van den Bent, and Annie Huang
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Summary:Pineal parenchymal tumors are rare neoplasms for which evidence-based treatment recommendations are lacking. These tumors vary in biology, clinical characteristics, and prognosis, requiring treatment that ranges from surgical resection alone to intensive multimodal antineoplastic therapy. Recently, international collaborative studies have shed light on the genomic landscape of these tumors, leading to refinement in molecular-based disease classification in the 5th edition of the World Health Organization (WHO) classification of tumors of the central nervous system. In this review, we summarize the literature on diagnostic and therapeutic approaches, and suggest pragmatic recommendations for the clinical management of patients presenting with intrinsic pineal region masses including parenchymal tumors (pineocytoma, pineal parenchymal tumor of intermediate differentiation, and pineoblastoma), pineal cyst, and papillary tumors of the pineal region.
Item Description:Veröffentlicht: 29. Juli 2024
Gesehen am 18.02.2025
Physical Description:Online Resource
ISSN:1523-5866
DOI:10.1093/neuonc/noae128

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