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Transcriptional pathways of terminal differentiation in high- and low-density blood granulocytes in sepsis

Trauma and infection induce emergency granulopoiesis. Counts of immature granulocytes and transcriptional pathways of terminal granulocytic differentiation in blood are elevated in sepsis but correlate with disease severity. This limits their performance as sepsis biomarkers in critically ill patien...

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Main Authors: Günther, Tobias (Author) , Coulibaly, Anna (Author) , Velásquez, Sonia Y. (Author) , Schulte, Jutta (Author) , Fuderer, Tanja (Author) , Sturm, Timo (Author) , Hahn, Bianka (Author) , Thiel, Manfred (Author) , Lindner, Holger A. (Author)
Format: Article (Journal)
Language:English
Published: 21 October 2024
In: Journal of Inflammation
Year: 2024, Volume: 21, Pages: 1-15
ISSN:1476-9255
DOI:10.1186/s12950-024-00414-w
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12950-024-00414-w
Verlag, kostenfrei, Volltext: https://journal-inflammation.biomedcentral.com/articles/10.1186/s12950-024-00414-w
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Author Notes:Tobias Guenther, Anna Coulibaly, Sonia Y. Velásquez, Jutta Schulte, Tanja Fuderer, Timo Sturm, Bianka Hahn, Manfred Thiel and Holger A. Lindner

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