Influence of gender on periodontal outcomes: A retrospective analysis of eight randomized clinical trials
AIMS: To explore the influence of gender on periodontal treatment outcomes in a dataset of eight RCTs conducted in Brazil, United States, and Germany. - METHODS: Clinical parameters were compared between men and women with stages III/IV grades B/C generalized periodontitis at baseline and 1-year pos...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
6 May 2024
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| In: |
Journal of periodontal research
Year: 2024, Jahrgang: 59, Heft: 6, Pages: 1175-1183 |
| ISSN: | 1600-0765 |
| DOI: | 10.1111/jre.13272 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1111/jre.13272
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| Verfasserangaben: | Nidia Castro Dos Santos, Miriam R. Westphal, Belen Retamal-Valdes, Poliana Mendes Duarte, Luciene Cristina Figueiredo, Marcelo Faveri, Jamil Shibli, Geisla Soares, Tamires Miranda, Daiane Fermiano, Ivan Borges, Cristiane Goncalves, Caio Junji Tanaka, Flavia Teles, Max Goodson, Hatice Hasturk, Thomas Van Dyke, Benjamin Ehmke, Peter Eickholz, Katrin Nickles, Ulrich Schlagenhauf, Joerg Meyle, Thomas Kocher, Ti-Sun Kim, Helio Doyle, Magda Feres |
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| 245 | 1 | 0 | |a Influence of gender on periodontal outcomes |b A retrospective analysis of eight randomized clinical trials |c Nidia Castro Dos Santos, Miriam R. Westphal, Belen Retamal-Valdes, Poliana Mendes Duarte, Luciene Cristina Figueiredo, Marcelo Faveri, Jamil Shibli, Geisla Soares, Tamires Miranda, Daiane Fermiano, Ivan Borges, Cristiane Goncalves, Caio Junji Tanaka, Flavia Teles, Max Goodson, Hatice Hasturk, Thomas Van Dyke, Benjamin Ehmke, Peter Eickholz, Katrin Nickles, Ulrich Schlagenhauf, Joerg Meyle, Thomas Kocher, Ti-Sun Kim, Helio Doyle, Magda Feres |
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| 520 | |a AIMS: To explore the influence of gender on periodontal treatment outcomes in a dataset of eight RCTs conducted in Brazil, United States, and Germany. - METHODS: Clinical parameters were compared between men and women with stages III/IV grades B/C generalized periodontitis at baseline and 1-year post-therapy, including scaling and root planing with or without antibiotics. - RESULTS: Data from 1042 patients were analyzed. Men presented a tendency towards higher probing depth (p = .07, effect size = 0.11) and clinical attachment level (CAL) than women at baseline (p = .01, effect size = 0.16). Males also presented statistically significantly lower CAL gain at sites with CAL of 4-6 mm at 1-year post-therapy (p = .001, effect size = 0.20). Among patients with Grade B periodontitis who took antibiotics, a higher frequency of women achieved the endpoint for treatment (i.e., ≤4 sites PD ≥5 mm) at 1 year than men (p < .05, effect size = 0.12). - CONCLUSION: Men enrolled in RCTs showed a slightly inferior clinical response to periodontal therapy in a limited number of sub-analyses when compared to women. These small differences did not appear to be clinically relevant. Although gender did not dictate the clinical response to periodontal treatment in this population, our findings suggest that future research should continue to explore this topic. | ||
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| 650 | 4 | |a Anti-Bacterial Agents | |
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| 650 | 4 | |a gender | |
| 650 | 4 | |a Humans | |
| 650 | 4 | |a Male | |
| 650 | 4 | |a Middle Aged | |
| 650 | 4 | |a periodontal attachment loss | |
| 650 | 4 | |a Periodontal Attachment Loss | |
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| 650 | 4 | |a Periodontitis | |
| 650 | 4 | |a Randomized Controlled Trials as Topic | |
| 650 | 4 | |a Retrospective Studies | |
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| 650 | 4 | |a sex | |
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