The difficulty in defining the true high-risk smoldering myeloma
Early intervention trials have been initiated for the precursor disease smoldering myeloma (SMM). A recent study showed that genomic complexity varies widely among patients treated for high-risk SMM and is associated with response to triplet therapy, suggesting that established clinical risk scores...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
1 October 2024
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| In: |
Clinical cancer research
Year: 2024, Jahrgang: 30, Heft: 19, Pages: 4263-4265 |
| ISSN: | 1557-3265 |
| DOI: | 10.1158/1078-0432.CCR-24-1382 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1158/1078-0432.CCR-24-1382 Verlag, lizenzpflichtig, Volltext: https://aacrjournals.org/clincancerres/article-abstract/30/19/4263/748542 
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| Verfasserangaben: | Niels Weinhold, Leo Rasche |
| Zusammenfassung: | Early intervention trials have been initiated for the precursor disease smoldering myeloma (SMM). A recent study showed that genomic complexity varies widely among patients treated for high-risk SMM and is associated with response to triplet therapy, suggesting that established clinical risk scores often fail to discriminate between stable and aggressive disease.See related article by Kazandjian et al., p. 4482 |
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| Beschreibung: | Gesehen am 22.04.2025 |
| Beschreibung: | Online Resource |
| ISSN: | 1557-3265 |
| DOI: | 10.1158/1078-0432.CCR-24-1382 |