Early recurrence or persistence of autoimmune diseases after unmanipulated autologous stem cell transplantation
Autologous stem cell transplantation with or without in vitro lymphocyte depletion has been suggested as a new treatment option for severe autoimmune diseases. We describe five patients with autoimmune diseases (CREST syndrome, myasthenia gravis and Hashimoto's thyroiditis, systemic lupus eryth...
Saved in:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
1 November 1996
|
| In: |
Blood
Year: 1996, Volume: 88, Issue: 9, Pages: 3621-3625 |
| ISSN: | 1528-0020 |
| DOI: | 10.1182/blood.V88.9.3621.bloodjournal8893621 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1182/blood.V88.9.3621.bloodjournal8893621 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0006497120613805 
|
| Author Notes: | Hans H. Euler, Alberto M. Marmont, Andrea Bacigalupo, Sven Fastenrath, Peter Dreger, Matthias Hoffknecht, Axel R. Zander, Berthold Schalke, Uwe Hahn, Rainer Haas, Norbert Schmitz |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1925351149 | ||
| 003 | DE-627 | ||
| 005 | 20250717013331.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 250512s1996 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1182/blood.V88.9.3621.bloodjournal8893621 |2 doi | |
| 035 | |a (DE-627)1925351149 | ||
| 035 | |a (DE-599)KXP1925351149 | ||
| 035 | |a (OCoLC)1528045359 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Euler, Hans Hartwig |e VerfasserIn |0 (DE-588)120903490 |0 (DE-627)705077012 |0 (DE-576)292439865 |4 aut | |
| 245 | 1 | 0 | |a Early recurrence or persistence of autoimmune diseases after unmanipulated autologous stem cell transplantation |c Hans H. Euler, Alberto M. Marmont, Andrea Bacigalupo, Sven Fastenrath, Peter Dreger, Matthias Hoffknecht, Axel R. Zander, Berthold Schalke, Uwe Hahn, Rainer Haas, Norbert Schmitz |
| 264 | 1 | |c 1 November 1996 | |
| 300 | |a 5 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Elektronische Reproduktion der Druck-Ausgabe 21. Dezember 2020 | ||
| 500 | |a Gesehen am 12.05.2025 | ||
| 520 | |a Autologous stem cell transplantation with or without in vitro lymphocyte depletion has been suggested as a new treatment option for severe autoimmune diseases. We describe five patients with autoimmune diseases (CREST syndrome, myasthenia gravis and Hashimoto's thyroiditis, systemic lupus erythematosus, atopic dermatitis, and rheumatoid arthritis) who underwent autologous bone marrow (n = 1) or peripheral blood progenitor cell (n = 4) transplantation with unmanipulated grafts as treatment for the autoimmune disease in one case or as treatment for a malignant disorder with a concomitant autoimmune disorder in four cases. In all patients serological and clinical signs of the autoimmune disease recurred early or persisted. These observations should be regarded as a cautionary note concerning the efficacy of high-dose therapy followed by transplantation of unmanipulated autologous stem cells for treatment of severe autoimmune diseases. | ||
| 700 | 1 | |a Marmont, Alberto M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Bacigalupo, Andrea |e VerfasserIn |4 aut | |
| 700 | 1 | |a Fastenrath, Sven |e VerfasserIn |4 aut | |
| 700 | 1 | |a Dreger, Peter |e VerfasserIn |0 (DE-588)1028891881 |0 (DE-627)732699894 |0 (DE-576)376320966 |4 aut | |
| 700 | 1 | |a Hoffknecht, Matthias Manfred |d 1958- |e VerfasserIn |0 (DE-588)1077111495 |0 (DE-627)836023749 |0 (DE-576)445976489 |4 aut | |
| 700 | 1 | |a Zander, Axel R. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Schalke, Berthold |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hahn, Uwe |d 1960- |e VerfasserIn |0 (DE-588)125272182X |0 (DE-627)179419102X |4 aut | |
| 700 | 1 | |a Haas, Rainer |d 1955- |e VerfasserIn |0 (DE-588)173773524 |0 (DE-627)698678141 |0 (DE-576)134613805 |4 aut | |
| 700 | 1 | |a Schmitz, Norbert |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Blood |d Washington, DC : American Society of Hematology, 1946 |g 88(1996), 9, Seite 3621-3625 |h Online-Ressource |w (DE-627)266886647 |w (DE-600)1468538-3 |w (DE-576)075961938 |x 1528-0020 |7 nnas |a Early recurrence or persistence of autoimmune diseases after unmanipulated autologous stem cell transplantation |
| 773 | 1 | 8 | |g volume:88 |g year:1996 |g number:9 |g pages:3621-3625 |g extent:5 |a Early recurrence or persistence of autoimmune diseases after unmanipulated autologous stem cell transplantation |
| 856 | 4 | 0 | |u https://doi.org/10.1182/blood.V88.9.3621.bloodjournal8893621 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.sciencedirect.com/science/article/pii/S0006497120613805 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20250512 | ||
| 993 | |a Article | ||
| 994 | |a 1996 | ||
| 998 | |g 173773524 |a Haas, Rainer |m 173773524:Haas, Rainer |d 910000 |d 910100 |e 910000PH173773524 |e 910100PH173773524 |k 0/910000/ |k 1/910000/910100/ |p 10 | ||
| 998 | |g 125272182X |a Hahn, Uwe |m 125272182X:Hahn, Uwe |d 910000 |d 910100 |e 910000PH125272182X |e 910100PH125272182X |k 0/910000/ |k 1/910000/910100/ |p 9 | ||
| 999 | |a KXP-PPN1925351149 |e 4723605894 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"id":{"eki":["1925351149"],"doi":["10.1182/blood.V88.9.3621.bloodjournal8893621"]},"title":[{"title":"Early recurrence or persistence of autoimmune diseases after unmanipulated autologous stem cell transplantation","title_sort":"Early recurrence or persistence of autoimmune diseases after unmanipulated autologous stem cell transplantation"}],"recId":"1925351149","note":["Elektronische Reproduktion der Druck-Ausgabe 21. Dezember 2020","Gesehen am 12.05.2025"],"physDesc":[{"extent":"5 S."}],"person":[{"family":"Euler","roleDisplay":"VerfasserIn","role":"aut","display":"Euler, Hans Hartwig","given":"Hans Hartwig"},{"family":"Marmont","roleDisplay":"VerfasserIn","role":"aut","display":"Marmont, Alberto M.","given":"Alberto M."},{"family":"Bacigalupo","roleDisplay":"VerfasserIn","display":"Bacigalupo, Andrea","role":"aut","given":"Andrea"},{"family":"Fastenrath","roleDisplay":"VerfasserIn","given":"Sven","role":"aut","display":"Fastenrath, Sven"},{"family":"Dreger","roleDisplay":"VerfasserIn","display":"Dreger, Peter","role":"aut","given":"Peter"},{"display":"Hoffknecht, Matthias Manfred","role":"aut","given":"Matthias Manfred","family":"Hoffknecht","roleDisplay":"VerfasserIn"},{"roleDisplay":"VerfasserIn","family":"Zander","display":"Zander, Axel R.","role":"aut","given":"Axel R."},{"display":"Schalke, Berthold","role":"aut","given":"Berthold","roleDisplay":"VerfasserIn","family":"Schalke"},{"role":"aut","display":"Hahn, Uwe","given":"Uwe","roleDisplay":"VerfasserIn","family":"Hahn"},{"roleDisplay":"VerfasserIn","family":"Haas","role":"aut","display":"Haas, Rainer","given":"Rainer"},{"family":"Schmitz","roleDisplay":"VerfasserIn","display":"Schmitz, Norbert","role":"aut","given":"Norbert"}],"name":{"displayForm":["Hans H. Euler, Alberto M. Marmont, Andrea Bacigalupo, Sven Fastenrath, Peter Dreger, Matthias Hoffknecht, Axel R. Zander, Berthold Schalke, Uwe Hahn, Rainer Haas, Norbert Schmitz"]},"relHost":[{"id":{"eki":["266886647"],"zdb":["1468538-3"],"issn":["1528-0020"]},"title":[{"subtitle":"journal of the American Society of Hematology","title":"Blood","title_sort":"Blood"}],"disp":"Early recurrence or persistence of autoimmune diseases after unmanipulated autologous stem cell transplantationBlood","note":["Gesehen am 21.04.2023"],"language":["eng"],"origin":[{"publisher":"American Society of Hematology ; Saunders ; HighWire Press","dateIssuedKey":"1946","publisherPlace":"Washington, DC ; Philadelphia, Pa. ; Stanford, Calif.","dateIssuedDisp":"1946-"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"part":{"volume":"88","issue":"9","text":"88(1996), 9, Seite 3621-3625","pages":"3621-3625","year":"1996","extent":"5"},"physDesc":[{"extent":"Online-Ressource"}],"recId":"266886647","titleAlt":[{"title":"Blood online"}],"pubHistory":["1.1946 -"],"corporate":[{"roleDisplay":"Herausgebendes Organ","display":"American Society of Hematology","role":"isb"}]}],"language":["eng"],"origin":[{"dateIssuedDisp":"1 November 1996","dateIssuedKey":"1996"}],"type":{"bibl":"article-journal","media":"Online-Ressource"}} | ||
| SRT | |a EULERHANSHEARLYRECUR1199 | ||