Going beyond the 2023 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting
The MASCC/ESMO guidelines for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting were updated in 2023 by a Consensus Committee of 34 multidisciplinary international healthcare professionals and three patient advocates. Guideline-recommended prophylactic anti-emetic strategi...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
3 June 2025
|
| In: |
European journal of cancer
Year: 2025, Volume: 222, Pages: 1-8 |
| ISSN: | 1879-0852 |
| DOI: | 10.1016/j.ejca.2025.115451 |
| Online Access: | Resolving-System, kostenfrei: https://doi.org/10.1016/j.ejca.2025.115451 Resolving-System, kostenfrei: https://doi.org/10.25673/119122 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0959804925002321 
|
| Author Notes: | Karin Jordan, Evandro de Azambuja, María Ángeles García Del Barrio, Franziska Jahn, Mario Di Palma, Florian Scotté, Alex Molassiotis, Matti Aapro |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1925743934 | ||
| 003 | DE-627 | ||
| 005 | 20260211133451.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 250515s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.ejca.2025.115451 |2 doi | |
| 024 | 7 | |a 10.25673/119122 |2 doi | |
| 035 | |a (DE-627)1925743934 | ||
| 035 | |a (DE-599)KXP1925743934 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Jordan, Karin |d 1974- |e VerfasserIn |0 (DE-588)123243327 |0 (DE-627)706224078 |0 (DE-576)293619174 |4 aut | |
| 245 | 1 | 0 | |a Going beyond the 2023 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting |c Karin Jordan, Evandro de Azambuja, María Ángeles García Del Barrio, Franziska Jahn, Mario Di Palma, Florian Scotté, Alex Molassiotis, Matti Aapro |
| 264 | 1 | |c 3 June 2025 | |
| 300 | |a 8 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 05.11.2025 | ||
| 520 | |a The MASCC/ESMO guidelines for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting were updated in 2023 by a Consensus Committee of 34 multidisciplinary international healthcare professionals and three patient advocates. Guideline-recommended prophylactic anti-emetic strategies can control chemotherapy-induced nausea and vomiting (CINV) in many patients, but unaddressed issues remain. Across a series of meetings, we evaluated these guidelines to identify possible evidence gaps which warrant further exploration. Key topics identified and discussed included the use of dexamethasone-sparing regimens with cisplatin (and other non-anthracycline and cyclophosphamide)-based highly emetogenic chemotherapy regimens, the importance of individual patient risk factors for CINV, the use of a second agent in patients receiving low emetogenic chemotherapy, how to manage CINV with certain new antibody-drug conjugates, the most appropriate approach for managing breakthrough CINV, the options for patients with CINV even after following best guidance, the use of lower than standard doses of olanzapine (<10 mg/day), and the management of long-delayed CINV and CINV in patients receiving oral therapies. Through identifying the current gaps in the updated MASCC/ESMO guidelines and discussing the available evidence, we aim to address these issues and support oncologists who may encounter them in clinical practice. These and other questions need to be considered to help ensure choice of anti-emetic treatments provide optimal effectiveness in clinical practice. | ||
| 540 | |q DE-3 |a Namensnennung 4.0 International |f CC BY 4.0 |2 cc |u https://creativecommons.org/licenses/by/4.0/ | ||
| 650 | 4 | |a Anti-emetic therapy | |
| 650 | 4 | |a Chemotherapy- and radiotherapy-induced nausea and vomiting | |
| 650 | 4 | |a Emesis | |
| 650 | 4 | |a Guidelines | |
| 700 | 1 | |a de Azambuja, Evandro |e VerfasserIn |4 aut | |
| 700 | 1 | |a Del Barrio, María Ángeles García |e VerfasserIn |4 aut | |
| 700 | 1 | |a Jahn, Franziska |e VerfasserIn |0 (DE-588)1206295945 |0 (DE-627)1692290908 |4 aut | |
| 700 | 1 | |a Di Palma, Mario |e VerfasserIn |0 (DE-588)1375977032 |0 (DE-627)1935500171 |4 aut | |
| 700 | 1 | |a Scotté, Florian |e VerfasserIn |0 (DE-588)1188486284 |0 (DE-627)1667458728 |4 aut | |
| 700 | 1 | |a Molassiotis, Alex |e VerfasserIn |4 aut | |
| 700 | 1 | |a Aapro, Matti S. |d 1951- |e VerfasserIn |0 (DE-588)172799430 |0 (DE-627)697729990 |0 (DE-576)133655865 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t European journal of cancer |d Amsterdam [u.a.] : Elsevier, 1992 |g 222(2025) vom: Juni, Artikel-ID 115451, Seite 1-8 |w (DE-627)266883400 |w (DE-600)1468190-0 |w (DE-576)090954173 |x 1879-0852 |7 nnas |a Going beyond the 2023 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting |
| 773 | 1 | 8 | |g volume:222 |g year:2025 |g month:06 |g elocationid:115451 |g pages:1-8 |g extent:8 |a Going beyond the 2023 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.ejca.2025.115451 |x Resolving-System |z kostenfrei |7 0 |
| 856 | 4 | 0 | |u https://doi.org/10.25673/119122 |x Resolving-System |z kostenfrei |7 0 |
| 856 | 4 | 0 | |u https://www.sciencedirect.com/science/article/pii/S0959804925002321 |x Verlag |z lizenzpflichtig |3 Volltext |7 1 |
| 951 | |a AR | ||
| 992 | |a 20260211 | ||
| 993 | |a Article | ||
| 994 | |a 2025 | ||
| 998 | |g 123243327 |a Jordan, Karin |m 123243327:Jordan, Karin |d 50000 |e 50000PJ123243327 |k 0/50000/ |p 1 |x j | ||
| 999 | |a KXP-PPN1925743934 |e 4913104918 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"physDesc":[{"extent":"8 S."}],"id":{"doi":["10.1016/j.ejca.2025.115451","10.25673/119122"],"eki":["1925743934"]},"type":{"media":"Online-Ressource","bibl":"article-journal"},"note":["Gesehen am 05.11.2025"],"relHost":[{"recId":"266883400","disp":"Going beyond the 2023 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomitingEuropean journal of cancer","titleAlt":[{"title":"EJC online"}],"language":["eng"],"type":{"bibl":"periodical","media":"Online-Ressource"},"pubHistory":["28.1992 -"],"corporate":[{"display":"European Organization for Research on Treatment of Cancer","role":"isb"},{"display":"European Association for Cancer Research","role":"isb"},{"display":"European School of Oncology","role":"isb"}],"origin":[{"publisher":"Elsevier ; Pergamon Press","dateIssuedDisp":"1992-","dateIssuedKey":"1992","publisherPlace":"Amsterdam [u.a.] ; [Erscheinungsort nicht ermittelbar]"}],"title":[{"title_sort":"European journal of cancer","title":"European journal of cancer"}],"part":{"volume":"222","text":"222(2025) vom: Juni, Artikel-ID 115451, Seite 1-8","pages":"1-8","year":"2025","extent":"8"},"id":{"eki":["266883400"],"zdb":["1468190-0"],"issn":["1879-0852"]},"note":["Gesehen am 21.03.24","Ungezählte Beil.: Supplement"]}],"person":[{"role":"aut","family":"Jordan","given":"Karin","display":"Jordan, Karin"},{"role":"aut","display":"de Azambuja, Evandro","given":"Evandro","family":"de Azambuja"},{"family":"Del Barrio","given":"María Ángeles García","display":"Del Barrio, María Ángeles García","role":"aut"},{"role":"aut","family":"Jahn","given":"Franziska","display":"Jahn, Franziska"},{"given":"Mario","display":"Di Palma, Mario","family":"Di Palma","role":"aut"},{"family":"Scotté","given":"Florian","display":"Scotté, Florian","role":"aut"},{"display":"Molassiotis, Alex","given":"Alex","family":"Molassiotis","role":"aut"},{"role":"aut","family":"Aapro","given":"Matti S.","display":"Aapro, Matti S."}],"name":{"displayForm":["Karin Jordan, Evandro de Azambuja, María Ángeles García Del Barrio, Franziska Jahn, Mario Di Palma, Florian Scotté, Alex Molassiotis, Matti Aapro"]},"origin":[{"dateIssuedDisp":"3 June 2025","dateIssuedKey":"2025"}],"recId":"1925743934","title":[{"title_sort":"Going beyond the 2023 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting","title":"Going beyond the 2023 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting"}],"language":["eng"]} | ||
| SRT | |a JORDANKARIGOINGBEYON3202 | ||