Transcutaneous slowly depolarizing currents elicit pruritus in patients with atopic dermatitis
Slowly depolarizing currents applied for one minute have been shown to activate C-nociceptors and provoke increasing pain in patients with neuropathy. This study examined the effect of transcutaneous slowly depolarizing currents on pruritus in patients with atopic dermatitis. C-nociceptor-specific e...
Gespeichert in:
| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
October 2020
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| In: |
Acta dermato-venereologica
Year: 2020, Jahrgang: 100, Heft: 17, Pages: 1-6 |
| ISSN: | 1651-2057 |
| DOI: | 10.2340/00015555-3658 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.2340/00015555-3658 Verlag, lizenzpflichtig, Volltext: https://medicaljournalssweden.se/actadv/article/view/1817 
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| Verfasserangaben: | Roman Rukwied, Mark Schnakenberg, Hans Jürgen Solinkski, Martin Schmelz and Elke Weisshaar |
MARC
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| 520 | |a Slowly depolarizing currents applied for one minute have been shown to activate C-nociceptors and provoke increasing pain in patients with neuropathy. This study examined the effect of transcutaneous slowly depolarizing currents on pruritus in patients with atopic dermatitis. C-nociceptor-specific electrical stimu?lation was applied to areas of eczema-affected and non-affected skin in 26 patients with atopic dermatitis. Single half-sine wave pulses (500 ms, 0.2?1 mA) induced itch in 9 patients in eczema-affected areas of the skin (numerical rating scale 5???1), but pain in control skin (numerical rating scale 6???1).Sinusoidal stimuli (4 Hz, 10 pulses, 0.025?0.4 mA) evoked itch in only 3 patients in eczema-affected areas of the skin but on delivering pulses for one minute (0.05?0.2 mA) 48% of the patients (n=?12) reported itch with numerical rating scale 4???1 in areas of eczema-affected skin. The number of patients reporting itch in eczema-affected areas of the skin increased with longer stimulation (p? | ||
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