Intranasal oxytocin blunts amygdala response to negative affective stimuli in males and females with alcohol use disorder: a randomized controlled cross-over trial
Negative affect plays a prominent role in the maintenance of alcohol use disorder (AUD) and has been identified as a risk factor for relapse to alcohol. To date, however, treatment options that target negative affective states and consecutive relapse risk in AUD are insufficient. Oxytocin (OXY) migh...
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| Hauptverfasser: | , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
31 March 2025
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| In: |
Psychopharmacology
Year: 2025, Jahrgang: 242, Pages: 1995-2007 |
| ISSN: | 1432-2072 |
| DOI: | 10.1007/s00213-025-06779-x |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00213-025-06779-x
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| Verfasserangaben: | Sina Vetter, Sophia Schnabel, Matthias Reichl, Lea Sirignano, Valery Grinevich, Anne Koopmann, Rainer Spanagel, Falk Kiefer, Wolfgang Sommer, Patrick Bach |
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| 520 | |a Negative affect plays a prominent role in the maintenance of alcohol use disorder (AUD) and has been identified as a risk factor for relapse to alcohol. To date, however, treatment options that target negative affective states and consecutive relapse risk in AUD are insufficient. Oxytocin (OXY) might be a promising approach for addressing negative affective states and resulting motivation to use alcohol. | ||
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| 650 | 4 | |a Negative affect | |
| 650 | 4 | |a Oxytocin | |
| 650 | 4 | |a Positive Psychology | |
| 650 | 4 | |a Psychopharmacology | |
| 650 | 4 | |a Substance Abuse Disorder | |
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