OncomiR-181a promotes carcinogenesis by repressing the extracellular matrix proteoglycan decorin in hepatocellular carcinoma

Proteoglycans are important tumor microenvironment extracellular matrix components. The regulation of key proteoglycans, such as decorin (DCN), by miRNAs has drawn attention since they have surfaced as novel therapeutic targets in cancer. Accordingly, this study aimed at identifying the impact of mi...

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Hauptverfasser:	Assal, Reem Amr (VerfasserIn) , Abd El-bary, Rowan Bahaa El-din (VerfasserIn) , Youness, Rana A. (VerfasserIn) , Abdelrahman, Mohamed Mamdouh (VerfasserIn) , Zahran, Hala (VerfasserIn) , Hosny, Karim Adel (VerfasserIn) , Esmat, Gamal (VerfasserIn) , Breuhahn, Kai (VerfasserIn) , El-Ekiaby, Nada (VerfasserIn) , Fawzy, Injie Omar (VerfasserIn) , Abdelaziz, Ahmed Ihab (VerfasserIn)
Dokumenttyp:	Article (Journal)
Sprache:	Englisch
Veröffentlicht:	30 September 2024
In:	BMC gastroenterology Year: 2024, Jahrgang: 24, Pages: 1-14
ISSN:	1471-230X
DOI:	10.1186/s12876-024-03413-6
Online-Zugang:	Resolving-System, kostenfrei, Volltext: https://doi.org/10.1186/s12876-024-03413-6 Verlag, kostenfrei, Volltext: https://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-024-03413-6
Verfasserangaben:	Reem Amr Assal, Rowan Bahaa El-din Abd El-bary, Rana A. Youness, Mohamed Mamdouh Abdelrahman, Hala Zahran, Karim Adel Hosny, Gamal Esmat, Kai Breuhahn, Nada El-Ekiaby, Injie Omar Fawzy and Ahmed Ihab Abdelaziz