Reduced and standard field-of-view diffusion weighted imaging in patients with rectal cancer at 3 T: comparison of image quality and apparent diffusion coefficient measurements

Purpose - To compare a zoomed EPI-DWI (z-EPI) with a standard EPI-DWI (s-EPI) in the primary diagnostics of rectal cancer and assess its potential of reduced image artifacts. - Method - 22 therapy-naïve patients with rectal cancer underwent rectal MRI at a 3 T-system. The protocols consisted of a z...

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Main Authors: Attenberger, Ulrike (Author) , Tavakoli, Andrej (Author) , Stocker, Daniel (Author) , Stieb, Sonja (Author) , Riesterer, Oliver (Author) , Turina, Matthias (Author) , Schönberg, Stefan (Author) , Pilz, Lothar R. (Author) , Reiner, Caecilia Sophie (Author)
Format: Article (Journal)
Language:English
Published: October 2020
In: European journal of radiology
Year: 2020, Volume: 131, Pages: 1-8
ISSN:1872-7727
DOI:10.1016/j.ejrad.2020.109257
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ejrad.2020.109257
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0720048X20304460
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Author Notes:U.I. Attenberger, A. Tavakoli, D. Stocker, S. Stieb, O. Riesterer, M. Turina, S.O. Schoenberg, L. Pilz, C.S. Reiner

MARC

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520 |a Purpose - To compare a zoomed EPI-DWI (z-EPI) with a standard EPI-DWI (s-EPI) in the primary diagnostics of rectal cancer and assess its potential of reduced image artifacts. - Method - 22 therapy-naïve patients with rectal cancer underwent rectal MRI at a 3 T-system. The protocols consisted of a z-EPI DWI and s-EPI DWI sequence. Images were assessed by two independent and experienced readers regarding overall image quality and artifacts on a 5-point Likert scale, as well as overall sequence preference. In a lesion-based analysis, tumor and lymph node detection were rated on a 4-point Likert scale. Apparent diffusion coefficient (ADC) measurements were performed. - Results - Overall Image quality score for z-EPI and s-EPI showed no statistically significant differences (p = 0.80/0.54, reader 1/2) with a median score of 4 (“good” image quality) for both sequences. The image quality preference rank for z-EPI and s-EPI was given the category ‘no preference’ in 64 % (reader 1) and 50 % (reader 2). Most artifact-related scores (susceptibility, motion and distortion) did not show reproducible significant differences between z-EPI and s-EPI. The two sequences exhibited comparable, mostly good and excellent quality scores for tumor and lymph node detection (p = 0.19−0.99). ADC values were significantly lower for z-EPI than for s-EPI (p = 0.001/0.002, reader 1/2) with good agreement of ADC measurements between both readers. - Conclusion - Our data showed comparable image quality and lesion detection for the z-EPI and the s-EPI sequence in MRI of rectal cancer, whereas the mean ADC of the tumor was significantly lower in z-EPI compared to s-EPI. 
650 4 |a ADC 
650 4 |a Diffusion weighted MRI 
650 4 |a DWI 
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