Endovascular treatment for stroke due to occlusion of medium or distal vessels

In this trial involving 543 patients with stroke due to occlusion of medium or distal vessels, endovascular treatment within 24 hours after the onset of symptoms was not effective in improving functional outcome at 90 days.

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Bibliographic Details
Main Authors:	Psychogios, Marios-Nikos (Author) , Brehm, Alex (Author) , Ribo, Marc (Author) , Rizzo, Federica (Author) , Strbian, Daniel (Author) , Räty, Silja (Author) , Arenillas, Juan F. (Author) , Martínez-Galdámez, Mario (Author) , Hajdu, Steven D. (Author) , Michel, Patrik (Author) , Gralla, Jan (Author) , Piechowiak, Eike I. (Author) , Kaiser, Daniel P. O. (Author) , Puetz, Volker (Author) , Bergh, Frans Van den (Author) , Raedt, Sylvie De (Author) , Bellante, Flavio (Author) , Dusart, Anne (Author) , Hellstern, Victoria (Author) , Khanafer, Ali (Author) , Parrilla, Guillermo (Author) , Morales, Ana (Author) , Kirschke, Jan S. (Author) , Wunderlich, Silke (Author) , Fiehler, Jens (Author) , Thomalla, Götz (Author) , Lemmens, Robin (Author) , Peluso, Jo P. (Author) , Bolognese, Manuel (Author) , Hessling, Alexander von (Author) , Es, Adriaan van (Author) , Kruyt, Nyika D. (Author) , Coutinho, Jonathan M. (Author) , Castaño, Carlos (Author) , Minnerup, Jens (Author) , Zwam, Wim van (Author) , Dhondt, Elisabeth (Author) , Nolte, Christian H. (Author) , Machi, Paolo (Author) , Loehr, Christian (Author) , Mattle, Heinrich P. (Author) , Buhk, Jan-Hendrik (Author) , Kaesmacher, Johannes (Author) , Dobrocky, Tomas (Author) , Papanagiotou, Panagiotis (Author) , Alonso, Angelika (Author) , Holtmannspoetter, Markus (Author) , Zini, Andrea (Author) , Renieri, Leonardo (Author) , Keil, Fee (Author) , Wijngaard, Ido van den (Author) , Kägi, Georg (Author) , Terceño, Mikel (Author) , Wiesmann, Martin (Author) , Amaro, Sergio (Author) , Rommers, Nikki (Author) , Balmer, Luzia (Author) , Fragata, Isabel (Author) , Katan, Mira (Author) , Leker, Ronen R. (Author) , Saver, Jeffrey L. (Author) , Staals, Julie (Author) , Fischer, Urs (Author)
Format:	Article (Journal)
Language:	English
Published:	April 10, 2025
In:	The New England journal of medicine Year: 2025, Volume: 392, Issue: 14, Pages: 1374-1384
ISSN:	1533-4406
DOI:	10.1056/NEJMoa2408954
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1056/NEJMoa2408954 Verlag, lizenzpflichtig, Volltext: https://www.nejm.org/doi/full/10.1056/NEJMoa2408954
Author Notes:	M. Psychogios, A. Brehm, M. Ribo, F. Rizzo, D. Strbian, S. Räty, J.F. Arenillas, M. Martínez‑Galdámez, S.D. Hajdu, P. Michel, J. Gralla, E.I. Piechowiak, D.P.O. Kaiser, V. Puetz, F. Van den Bergh, S. De Raedt, F. Bellante, A. Dusart, V. Hellstern, A. Khanafer, G. Parrilla, A. Morales, J.S. Kirschke, S. Wunderlich, J. Fiehler, G. Thomalla, R. Lemmens, J.P. Peluso, M. Bolognese, A. von Hessling, A. van Es, N.D. Kruyt, J.M. Coutinho, C. Castaño, J. Minnerup, W. van Zwam, E. Dhondt, C.H. Nolte, P. Machi, C. Loehr, H.P. Mattle, J.‑H. Buhk, J. Kaesmacher, T. Dobrocky, P. Papanagiotou, A. Alonso, M. Holtmannspoetter, A. Zini, L. Renieri, F. Keil, I. van den Wijngaard, G. Kägi, M. Terceño, M. Wiesmann, S. Amaro, N. Rommers, L. Balmer,I. Fragata, M. Katan, R.R. Leker, J.L. Saver, J. Staals, and U. Fischer, for the DISTAL Investigators

Description
Summary:	In this trial involving 543 patients with stroke due to occlusion of medium or distal vessels, endovascular treatment within 24 hours after the onset of symptoms was not effective in improving functional outcome at 90 days.
Item Description:	Online veröffentlicht: 5. Februar 2025 Gesehen am 23.06.2025
Physical Description:	Online Resource
ISSN:	1533-4406
DOI:	10.1056/NEJMoa2408954