The relationship between stress and clinical high-risk symptoms of psychosis in daily life: impact of contemporaneous paths on cross-lagged effects

BackgroundThis study aimed to deepen the understanding of the psychological mechanisms underlying the formation and maintenance of clinical high-risk symptoms for psychosis (CHR-P) in real-life contexts. Specifically, it examined whether (i) momentary feelings of stress increase the frequency of CHR...

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Main Authors: Cavelti, Marialuisa (Author) , Kaeser, Janko M. (Author) , Sele, Silvano (Author) , Berger, Thomas (Author) , Kaess, Michael (Author) , Kindler, Jochen (Author) , Michel, Chantal (Author)
Format: Article (Journal)
Language:English
Published: 03 March 2025
In: Psychological medicine
Year: 2025, Volume: 55, Pages: 1-11
ISSN:1469-8978
DOI:10.1017/S0033291725000364
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1017/S0033291725000364
Verlag, kostenfrei, Volltext: https://www.cambridge.org/core/journals/psychological-medicine/article/relationship-between-stress-and-clinical-highrisk-symptoms-of-psychosis-in-daily-life-impact-of-contemporaneous-paths-on-crosslagged-effects/1C79E3A265DED2EC1FA1479875D4BC2F
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Author Notes:Marialuisa Cavelti, Janko M. Kaeser, Silvano Sele, Thomas Berger, Michael Kaess, Jochen Kindler and Chantal Michel

MARC

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520 |a BackgroundThis study aimed to deepen the understanding of the psychological mechanisms underlying the formation and maintenance of clinical high-risk symptoms for psychosis (CHR-P) in real-life contexts. Specifically, it examined whether (i) momentary feelings of stress increase the frequency of CHR-P symptoms, or conversely, (ii) CHR-P symptoms increase the intensity of stress. Additionally, potential moderators of the relationship between stress and CHR-P symptoms were explored.MethodsUsing Ecological Momentary Assessment, 79 patients (age: 11-36; 50.6% female) recruited from an early detection center for psychosis, reported their momentary stress levels and the frequency of CHR-P symptoms eight times a day for seven days. Time series data were analyzed using residual dynamic structural equation modeling in a random intercept cross-lagged panel design, comparing differently modeled contemporaneous effects.ResultsThere was no evidence of a contemporaneous or temporal link between stress on CHR-P symptoms. However, a contemporaneous effect of CHR-P symptoms on stress was found, while the corresponding temporal effect was not significant. The severity of interview-assessed CHR-P symptoms, age, and type of CHR-P symptoms (i.e., basic symptoms vs. [attenuated] positive symptoms) did not affect the contemporaneous effect of CHR-P symptoms on stress. However, nonperceptive symptoms had a greater contemporaneous effect on stress than perceptive symptoms.ConclusionsThe findings suggest a greater contemporaneous impact of CHR-P symptoms on stress than vice versa. The experience of nonperceptive symptoms, in particular, may alter the appraisal of stress in daily life and represent a target for early interventions in real-time daily life (i.e., ecological momentary interventions). 
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