l-Fucose residues on cellulose-based dialysis membranes: Quantification of membrane-associatedl-fucose and analysis of specific lectin binding
Contact of mononuclear human leukocytes with cellulose dialysis membranes may result in complement-independent cell activation, i.e. enhanced synthesis of cytokines, prostaglandins and an increase in β2-microglobulin synthesis. Cellular contact activation is specifically inhibited by the monosacchar...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
October 1995
|
| In: |
Glycoconjugate journal
Year: 1995, Volume: 12, Issue: 5, Pages: 632-638 |
| ISSN: | 1573-4986 |
| DOI: | 10.1007/BF00731258 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/BF00731258
|
| Author Notes: | Carsten Meißner, Reinhold Deppisch, Friederike Hug, Matthias Schulze, Eberhard Ritz, Horst Ludwig, Gertrud M. Hänsch |
MARC
| LEADER | 00000naa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1931942692 | ||
| 003 | DE-627 | ||
| 005 | 20250729084912.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 250729s1995 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/BF00731258 |2 doi | |
| 035 | |a (DE-627)1931942692 | ||
| 035 | |a (DE-599)KXP1931942692 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Meißner, Carsten |e VerfasserIn |0 (DE-588)135510341X |0 (DE-627)1916175244 |4 aut | |
| 245 | 1 | 0 | |a l-Fucose residues on cellulose-based dialysis membranes |b Quantification of membrane-associatedl-fucose and analysis of specific lectin binding |c Carsten Meißner, Reinhold Deppisch, Friederike Hug, Matthias Schulze, Eberhard Ritz, Horst Ludwig, Gertrud M. Hänsch |
| 264 | 1 | |c October 1995 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 29.07.2025 | ||
| 520 | |a Contact of mononuclear human leukocytes with cellulose dialysis membranes may result in complement-independent cell activation, i.e. enhanced synthesis of cytokines, prostaglandins and an increase in β2-microglobulin synthesis. Cellular contact activation is specifically inhibited by the monosaccharidel-fucose suggesting that dialysis membrane associatedl-fucose residues are involved in leukocyte activation. In this study we have detected and quantitatedl-fucose on commercially-available cellulose dialysis membranes using two approaches. A sensitive enzymatic fluorescence assay detectedl-fucose after acid hydrolysis of flat sheet membranes. Values ranged from 79.3±3.6 to 90.2±5.0 pmol cm−2 for Hemophan® or Cuprophan® respectively. Enzymatic cleavage of terminal α-l-fucopyranoses with α-l-fucosidase yielded 7.7±3.3 pmoll-fucose per cm2 for Cuprophan. Enzymatic hydrolysis of the synthetic polymer membranes AN-69 and PC-PE did not yield detectable amounts ofl-fucose. In a second approach, binding of the fucose specific lectins ofLotus tetragonolobus andUlex europaeus (UEAI) demonstrated the presence of biologically accessiblel-fucose on the surface of cellulose membranes. Specific binding was observed with Cuprophan®, and up to 2.6±0.3 pmoll-fucose per cm2 was calculated to be present from Langmuir-type adsorption isotherms. The data presented are in line with the hypothesis that surface-associatedl-fucose residues on cellulose dialysis membranes participate in leukocyte contact activation. | ||
| 650 | 4 | |a biocompatibility | |
| 650 | 4 | |a Cell wall | |
| 650 | 4 | |a dialysis membranes | |
| 650 | 4 | |a Glycobiology | |
| 650 | 4 | |a Glycomics | |
| 650 | 4 | |a Glycoside | |
| 650 | 4 | |a Glycosylation | |
| 650 | 4 | |a haemodialysis | |
| 650 | 4 | |a L-fucose | |
| 650 | 4 | |a Polysaccharide sequencing | |
| 700 | 1 | |a Deppisch, Reinhold |e VerfasserIn |0 (DE-588)143705067 |0 (DE-627)704576627 |0 (DE-576)170814386 |4 aut | |
| 700 | 1 | |a Hug, Friederike |e VerfasserIn |0 (DE-588)1145068014 |0 (DE-627)1005287600 |0 (DE-576)495605328 |4 aut | |
| 700 | 1 | |a Schulze, Matthias |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ritz, Eberhard |d 1938-2023 |e VerfasserIn |0 (DE-588)106673386 |0 (DE-627)610528866 |0 (DE-576)311552501 |4 aut | |
| 700 | 1 | |a Ludwig, Horst |d 1937- |e VerfasserIn |0 (DE-588)1130791734 |0 (DE-627)88518274X |0 (DE-576)487006712 |4 aut | |
| 700 | 1 | |a Hänsch, Gertrud Maria |e VerfasserIn |0 (DE-588)1032383380 |0 (DE-627)738394076 |0 (DE-576)323810926 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Glycoconjugate journal |d Dordrecht [u.a.] : Springer Science + Business Media B.V, 1984 |g 12(1995), 5, Seite 632-638 |h Online-Ressource |w (DE-627)300898827 |w (DE-600)1483682-8 |w (DE-576)110279093 |x 1573-4986 |7 nnas |a l-Fucose residues on cellulose-based dialysis membranes Quantification of membrane-associatedl-fucose and analysis of specific lectin binding |
| 773 | 1 | 8 | |g volume:12 |g year:1995 |g number:5 |g pages:632-638 |g extent:7 |a l-Fucose residues on cellulose-based dialysis membranes Quantification of membrane-associatedl-fucose and analysis of specific lectin binding |
| 856 | 4 | 0 | |u https://doi.org/10.1007/BF00731258 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20250729 | ||
| 993 | |a Article | ||
| 994 | |a 1995 | ||
| 998 | |g 1032383380 |a Hänsch, Gertrud Maria |m 1032383380:Hänsch, Gertrud Maria |d 910000 |d 911600 |e 910000PH1032383380 |e 911600PH1032383380 |k 0/910000/ |k 1/910000/911600/ |p 7 |y j | ||
| 998 | |g 1130791734 |a Ludwig, Horst |m 1130791734:Ludwig, Horst |d 170000 |d 170200 |d 160000 |d 160100 |e 170000PL1130791734 |e 170200PL1130791734 |e 160000PL1130791734 |e 160100PL1130791734 |k 0/170000/ |k 1/170000/170200/ |k 0/160000/ |k 1/160000/160100/ |p 6 | ||
| 998 | |g 106673386 |a Ritz, Eberhard |m 106673386:Ritz, Eberhard |d 910000 |d 910100 |e 910000PR106673386 |e 910100PR106673386 |k 0/910000/ |k 1/910000/910100/ |p 5 | ||
| 998 | |g 1145068014 |a Hug, Friederike |m 1145068014:Hug, Friederike |d 910000 |d 911600 |e 910000PH1145068014 |e 911600PH1145068014 |k 0/910000/ |k 1/910000/911600/ |p 3 | ||
| 998 | |g 135510341X |a Meißner, Carsten |m 135510341X:Meißner, Carsten |d 50000 |e 50000PM135510341X |k 0/50000/ |p 1 |x j | ||
| 999 | |a KXP-PPN1931942692 |e 4750388785 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1931942692","id":{"eki":["1931942692"],"doi":["10.1007/BF00731258"]},"origin":[{"dateIssuedKey":"1995","dateIssuedDisp":"October 1995"}],"relHost":[{"disp":"l-Fucose residues on cellulose-based dialysis membranes Quantification of membrane-associatedl-fucose and analysis of specific lectin bindingGlycoconjugate journal","part":{"volume":"12","pages":"632-638","extent":"7","year":"1995","issue":"5","text":"12(1995), 5, Seite 632-638"},"pubHistory":["1.1984 -"],"type":{"bibl":"periodical","media":"Online-Ressource"},"recId":"300898827","title":[{"title_sort":"Glycoconjugate journal","title":"Glycoconjugate journal","subtitle":"official journal of the International Glycoconjugate Organization"}],"physDesc":[{"extent":"Online-Ressource"}],"language":["eng"],"note":["Gesehen am 11.10.05"],"origin":[{"publisher":"Springer Science + Business Media B.V ; Kluwer","dateIssuedKey":"1984","dateIssuedDisp":"1984-","publisherPlace":"Dordrecht [u.a.] ; Dordrecht [u.a.]"}],"id":{"zdb":["1483682-8"],"eki":["300898827"],"issn":["1573-4986"]}}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"person":[{"family":"Meißner","display":"Meißner, Carsten","role":"aut","given":"Carsten"},{"given":"Reinhold","display":"Deppisch, Reinhold","family":"Deppisch","role":"aut"},{"role":"aut","display":"Hug, Friederike","family":"Hug","given":"Friederike"},{"given":"Matthias","role":"aut","display":"Schulze, Matthias","family":"Schulze"},{"given":"Eberhard","family":"Ritz","display":"Ritz, Eberhard","role":"aut"},{"given":"Horst","role":"aut","display":"Ludwig, Horst","family":"Ludwig"},{"display":"Hänsch, Gertrud Maria","family":"Hänsch","role":"aut","given":"Gertrud Maria"}],"name":{"displayForm":["Carsten Meißner, Reinhold Deppisch, Friederike Hug, Matthias Schulze, Eberhard Ritz, Horst Ludwig, Gertrud M. Hänsch"]},"note":["Gesehen am 29.07.2025"],"title":[{"title":"l-Fucose residues on cellulose-based dialysis membranes","subtitle":"Quantification of membrane-associatedl-fucose and analysis of specific lectin binding","title_sort":"l-Fucose residues on cellulose-based dialysis membranes"}],"language":["eng"],"physDesc":[{"extent":"7 S."}]} | ||
| SRT | |a MEISSNERCALFUCOSERES1995 | ||