Developing a cosmetic series: results from the ESSCA network, 2009-2018
Background There is considerable variability across European patch test centres as to which allergens are included in local and national cosmetics series. Objectives To propose a standardized, evidence-based cosmetic series for Europe based on up-to-date analysis of relevant contact allergens. Metho...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
24 January 2021
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| In: |
Contact dermatitis
Year: 2021, Volume: 84, Issue: 2, Pages: 82-94 |
| ISSN: | 1600-0536 |
| DOI: | 10.1111/cod.13690 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1111/cod.13690 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/cod.13690 
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| Author Notes: | Emma Horton, Wolfgang Uter, Johannes Geier, Barbara Ballmer-Weber, Andrea Bauer, Andreas Bircher, Heinrich Dickel, Ana Giménez-Arnau, Margarida Gonçalo, Swen Malte John, Vera Mahler, Marie L. A. Schuttelaar, Dagmar Simon, Javier Sanchez-Perez, Thomas Rustemeyer, Elke Weisshaar, Mark Wilkinson |
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| 245 | 1 | 0 | |a Developing a cosmetic series |b results from the ESSCA network, 2009-2018 |c Emma Horton, Wolfgang Uter, Johannes Geier, Barbara Ballmer-Weber, Andrea Bauer, Andreas Bircher, Heinrich Dickel, Ana Giménez-Arnau, Margarida Gonçalo, Swen Malte John, Vera Mahler, Marie L. A. Schuttelaar, Dagmar Simon, Javier Sanchez-Perez, Thomas Rustemeyer, Elke Weisshaar, Mark Wilkinson |
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| 520 | |a Background There is considerable variability across European patch test centres as to which allergens are included in local and national cosmetics series. Objectives To propose a standardized, evidence-based cosmetic series for Europe based on up-to-date analysis of relevant contact allergens. Methods We collated data from the European Surveillance System on Contact Allergies (ESSCA) from 2009 to 2018 to determine which cosmetic allergens produce a high yield of contact allergy. Contact allergens with a prevalence of >0.3% that were considered relevant were included. Rare contact allergens were excluded if deemed no longer relevant or added to a supplemental cosmetic series for further analysis. Results Sensitization prevalences of 39 cosmetic contact allergens were tabulated. Thirty of these allergens yielded >0.3% positive reactions and are therefore included in our proposed European cosmetic series. Six were considered no longer relevant and therefore excluded. Three were included in a supplementary European cosmetic series. An additional nine allergens were included in either the core or supplemental European cosmetic series following literature review. Conclusion We have derived a potential European cosmetic series based upon the above methods. This will require ongoing investigation based upon the changing exposure profiles of cosmetic allergens as well as new and evolving substances. | ||
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