Guiding principles for the use of knowledge bases and real-world data in clinical decision support systems: report by an international expert workshop at Karolinska Institutet
Technical and logical breakthroughs have provided new opportunities in medicine to use knowledge bases and large-scale clinical data (real-world) at point-of-care as part of a learning healthcare system to diminish the knowledge-practice gap. The article is based on presentations, discussions and re...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
29 Sep 2020
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| In: |
Expert review of clinical pharmacology
Year: 2020, Jahrgang: 13, Heft: 9, Pages: 925-934 |
| ISSN: | 1751-2441 |
| DOI: | 10.1080/17512433.2020.1805314 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1080/17512433.2020.1805314 Verlag, kostenfrei, Volltext: https://www.tandfonline.com/doi/full/10.1080/17512433.2020.1805314 
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| Verfasserangaben: | Mikael Hoffmann, Robert Vander Stichele, David W Bates, Johanna Björklund, Steve Alexander, Marine L Andersson, Ane Auraaen, Marion Bennie, Marja-Liisa Dahl, Birgit Eiermann, Werner Hackl, Tora Hammar, Paul Hjemdahl, Sabine Koch, Ilkka Kunnamo, Herve Le Louët, Papapetrou Panagiotis, Lembit Rägo, Michael Spedding, Hanna M Seidling, Dina Demner-Fushman and Lars L Gustafsson |
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| 520 | |a Technical and logical breakthroughs have provided new opportunities in medicine to use knowledge bases and large-scale clinical data (real-world) at point-of-care as part of a learning healthcare system to diminish the knowledge-practice gap. The article is based on presentations, discussions and recommendations from an international scientific workshop. Value, research needs and funding avenues of knowledge bases and access to real-world data as well as transparency and incorporation of patient perspectives are discussed. Evidence-based, publicly funded, well-structured and curated knowledge bases are of global importance. They ought to be considered as a public responsibility requiring transparency and handling of conflicts of interest. Information has to be made accessible for clinical decision support systems (CDSS) for healthcare staff and patients. Access to rich and real-world data is essential for a learning health care ecosystem and can be augmented by data on patient-reported outcomes and preferences. This field can progress by the establishment of an international policy group for developing a best practice guideline on the development, maintenance, governance, evaluation principles and financing of open-source knowledge bases and handling of real-world data. | ||
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