Hospital volume and outcome in the treatment of congenital diaphragmatic hernia in Germany: observational study using national hospital discharge data from 2016 to 2023

Background - Congenital diaphragmatic hernia (CDH) is a critical malformation, with the neonatal period being particularly challenging and associated with high mortality. Data on the care structure and volume-outcome relationship in the treatment of children with CDH in Germany remain scarce. - Meth...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Elrod, Julia (VerfasserIn) , Boettcher, Michael (VerfasserIn) , Kipfmüller, Florian (VerfasserIn) , Schaible, Thomas (VerfasserIn) , Wolfram Trudo, Knoefel (VerfasserIn) , Mohr, Christoph (VerfasserIn) , Herwig, Ramona (VerfasserIn) , Samans, Max (VerfasserIn) , Busse, Reinhard (VerfasserIn) , Nimptsch, Ulrike (VerfasserIn) , Wilms, Miriam (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: September 2025
In: Journal of pediatric surgery
Year: 2025, Jahrgang: 60, Heft: 9, Pages: 1-10
ISSN:1531-5037
DOI:10.1016/j.jpedsurg.2025.162399
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.jpedsurg.2025.162399
Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S0022346825002441
Volltext
Verfasserangaben:Julia Elrod, Michael Boettcher, Florian Kipfmueller, Thomas Schaible, Knoefel Wolfram Trudo, Christoph Mohr, Ramona Herwig, Max Samans, Reinhard Busse, Ulrike Nimptsch, Miriam Wilms

MARC

LEADER 00000caa a2200000 c 4500
001 1933550732
003 DE-627
005 20251201123741.0
007 cr uuu---uuuuu
008 250819s2025 xx |||||o 00| ||eng c
024 7 |a 10.1016/j.jpedsurg.2025.162399  |2 doi 
035 |a (DE-627)1933550732 
035 |a (DE-599)KXP1933550732 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Elrod, Julia  |d 1987-  |e VerfasserIn  |0 (DE-588)1094920886  |0 (DE-627)855379847  |0 (DE-576)462865916  |4 aut 
245 1 0 |a Hospital volume and outcome in the treatment of congenital diaphragmatic hernia in Germany  |b observational study using national hospital discharge data from 2016 to 2023  |c Julia Elrod, Michael Boettcher, Florian Kipfmueller, Thomas Schaible, Knoefel Wolfram Trudo, Christoph Mohr, Ramona Herwig, Max Samans, Reinhard Busse, Ulrike Nimptsch, Miriam Wilms 
264 1 |c September 2025 
300 |b Illustrationen 
300 |a 10 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Online verfügbar: 7. Juni 2025, Artikelversion: 18. Juni 2025 
500 |a Gesehen am 19.08.2025 
520 |a Background - Congenital diaphragmatic hernia (CDH) is a critical malformation, with the neonatal period being particularly challenging and associated with high mortality. Data on the care structure and volume-outcome relationship in the treatment of children with CDH in Germany remain scarce. - Methods - This study determined case numbers and outcomes of treatment of children aged 0-17 years, with CDH in Germany between 2016 and 2023 through a query of the nationwide DRG database at the Research Data Center of the Federal Statistical Office. Using the ICD-10 and OPS codes, inpatient cases with and without ECMO treatment were identified. The analysis included patient characteristics, hospital caseload, treatment characteristics and outcome parameters stratified by hospital caseload. - Results - In the 8 years, a total of 1470 newborns with CDH were born across 234 different hospitals, with a median annual caseload of 1 (IQR: 1-2). In-hospital mortality was 22.5 %. Corrective surgery was performed in 1539 cases across 103 hospitals. Mortality among patients who underwent corrective surgery was 4.8 % in low-volume centers, 5.3 % in medium-volume centers, and 9.6 % in high-volume centers. A higher ECMO frequency was observed in high-volume centers (32.2 % vs. 5.4 % in medium-volume and 1.9 % in low-volume). Among all ECMO-treated CDH patients, regardless of corrective surgery, mortality was 60.0 %, 40.0 %, and 36.5 % in low-, medium-, and high-volume centers, respectively. - Conclusions - These findings indicate that high-volume centers treat a greater proportion of severe cases and that they may achieve better outcomes for the most critically ill patients, as reflected by lower ECMO-specific mortality. 
650 4 |a Case load 
650 4 |a Congenital diaphragmatic hernia 
650 4 |a ECMO 
650 4 |a Mortality 
650 4 |a Volume-outcome 
700 1 |a Boettcher, Michael  |d 1982-  |e VerfasserIn  |0 (DE-588)138309566  |0 (DE-627)696492113  |0 (DE-576)306510219  |4 aut 
700 1 |a Kipfmüller, Florian  |e VerfasserIn  |0 (DE-588)1216058318  |0 (DE-627)1727152611  |4 aut 
700 1 |a Schaible, Thomas  |d 1960-  |e VerfasserIn  |0 (DE-588)1026440440  |0 (DE-627)726733342  |0 (DE-576)371782333  |4 aut 
700 1 |a Wolfram Trudo, Knoefel  |e VerfasserIn  |4 aut 
700 1 |a Mohr, Christoph  |e VerfasserIn  |4 aut 
700 1 |a Herwig, Ramona  |e VerfasserIn  |4 aut 
700 1 |a Samans, Max  |e VerfasserIn  |4 aut 
700 1 |a Busse, Reinhard  |e VerfasserIn  |4 aut 
700 1 |a Nimptsch, Ulrike  |e VerfasserIn  |4 aut 
700 1 |a Wilms, Miriam  |e VerfasserIn  |4 aut 
773 0 8 |i Enthalten in  |t Journal of pediatric surgery  |d Orlando, Fla. : Elsevier, 1966  |g 60(2025), 9 vom: Sept., Artikel-ID 162399, Seite 1-10  |h Online-Ressource  |w (DE-627)325699542  |w (DE-600)2039299-0  |w (DE-576)094422338  |x 1531-5037  |7 nnas  |a Hospital volume and outcome in the treatment of congenital diaphragmatic hernia in Germany observational study using national hospital discharge data from 2016 to 2023 
773 1 8 |g volume:60  |g year:2025  |g number:9  |g month:09  |g elocationid:162399  |g pages:1-10  |g extent:10  |a Hospital volume and outcome in the treatment of congenital diaphragmatic hernia in Germany observational study using national hospital discharge data from 2016 to 2023 
856 4 0 |u https://doi.org/10.1016/j.jpedsurg.2025.162399  |x Verlag  |x Resolving-System  |z kostenfrei  |3 Volltext 
856 4 0 |u https://www.sciencedirect.com/science/article/pii/S0022346825002441  |x Verlag  |z kostenfrei  |3 Volltext 
951 |a AR 
992 |a 20250819 
993 |a Article 
994 |a 2025 
998 |g 1026440440  |a Schaible, Thomas  |m 1026440440:Schaible, Thomas  |d 60000  |d 62500  |e 60000PS1026440440  |e 62500PS1026440440  |k 0/60000/  |k 1/60000/62500/  |p 4 
998 |g 1216058318  |a Kipfmüller, Florian  |m 1216058318:Kipfmüller, Florian  |d 60000  |d 62500  |e 60000PK1216058318  |e 62500PK1216058318  |k 0/60000/  |k 1/60000/62500/  |p 3 
998 |g 138309566  |a Boettcher, Michael  |m 138309566:Boettcher, Michael  |d 60000  |d 62200  |e 60000PB138309566  |e 62200PB138309566  |k 0/60000/  |k 1/60000/62200/  |p 2 
998 |g 1094920886  |a Elrod, Julia  |m 1094920886:Elrod, Julia  |d 60000  |d 62200  |e 60000PE1094920886  |e 62200PE1094920886  |k 0/60000/  |k 1/60000/62200/  |p 1  |x j 
999 |a KXP-PPN1933550732  |e 4758960364 
BIB |a Y 
SER |a journal 
JSO |a {"language":["eng"],"person":[{"given":"Julia","role":"aut","family":"Elrod","display":"Elrod, Julia"},{"role":"aut","given":"Michael","family":"Boettcher","display":"Boettcher, Michael"},{"display":"Kipfmüller, Florian","family":"Kipfmüller","role":"aut","given":"Florian"},{"family":"Schaible","display":"Schaible, Thomas","given":"Thomas","role":"aut"},{"role":"aut","given":"Knoefel","display":"Wolfram Trudo, Knoefel","family":"Wolfram Trudo"},{"family":"Mohr","display":"Mohr, Christoph","given":"Christoph","role":"aut"},{"family":"Herwig","display":"Herwig, Ramona","given":"Ramona","role":"aut"},{"role":"aut","given":"Max","display":"Samans, Max","family":"Samans"},{"given":"Reinhard","role":"aut","family":"Busse","display":"Busse, Reinhard"},{"role":"aut","given":"Ulrike","display":"Nimptsch, Ulrike","family":"Nimptsch"},{"given":"Miriam","role":"aut","family":"Wilms","display":"Wilms, Miriam"}],"name":{"displayForm":["Julia Elrod, Michael Boettcher, Florian Kipfmueller, Thomas Schaible, Knoefel Wolfram Trudo, Christoph Mohr, Ramona Herwig, Max Samans, Reinhard Busse, Ulrike Nimptsch, Miriam Wilms"]},"physDesc":[{"noteIll":"Illustrationen","extent":"10 S."}],"recId":"1933550732","relHost":[{"id":{"zdb":["2039299-0"],"issn":["1531-5037"],"eki":["325699542"]},"recId":"325699542","physDesc":[{"extent":"Online-Ressource"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Hospital volume and outcome in the treatment of congenital diaphragmatic hernia in Germany observational study using national hospital discharge data from 2016 to 2023Journal of pediatric surgery","origin":[{"publisherPlace":"Orlando, Fla. ; Philadelphia, Pa.","publisher":"Elsevier ; Saunders","dateIssuedKey":"1966","dateIssuedDisp":"1966-"}],"pubHistory":["1.1966 -"],"note":["Gesehen am 19.02.20"],"title":[{"subtitle":"official journal of the Section on Surgery of the American Academy of Pediatrics, British Association of Paediatric Surgeons, American Pediatric Surgical Association. Canadian Association of Paediatric Surgeons and the Pacific Association of Pediatric Surgeons","title_sort":"Journal of pediatric surgery","title":"Journal of pediatric surgery"}],"part":{"text":"60(2025), 9 vom: Sept., Artikel-ID 162399, Seite 1-10","issue":"9","year":"2025","pages":"1-10","extent":"10","volume":"60"},"language":["eng"],"corporate":[{"display":"American Academy of Pediatrics","role":"isb"},{"role":"isb","display":"British Association of Paediatric Surgeons"}]}],"id":{"eki":["1933550732"],"doi":["10.1016/j.jpedsurg.2025.162399"]},"note":["Online verfügbar: 7. Juni 2025, Artikelversion: 18. Juni 2025","Gesehen am 19.08.2025"],"origin":[{"dateIssuedKey":"2025","dateIssuedDisp":"September 2025"}],"title":[{"title":"Hospital volume and outcome in the treatment of congenital diaphragmatic hernia in Germany","title_sort":"Hospital volume and outcome in the treatment of congenital diaphragmatic hernia in Germany","subtitle":"observational study using national hospital discharge data from 2016 to 2023"}],"type":{"bibl":"article-journal","media":"Online-Ressource"}} 
SRT |a ELRODJULIAHOSPITALVO2025