Hospital volume and outcome in the treatment of congenital diaphragmatic hernia in Germany: observational study using national hospital discharge data from 2016 to 2023
Background - Congenital diaphragmatic hernia (CDH) is a critical malformation, with the neonatal period being particularly challenging and associated with high mortality. Data on the care structure and volume-outcome relationship in the treatment of children with CDH in Germany remain scarce. - Meth...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
September 2025
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| In: |
Journal of pediatric surgery
Year: 2025, Jahrgang: 60, Heft: 9, Pages: 1-10 |
| ISSN: | 1531-5037 |
| DOI: | 10.1016/j.jpedsurg.2025.162399 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.jpedsurg.2025.162399 Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S0022346825002441 |
| Verfasserangaben: | Julia Elrod, Michael Boettcher, Florian Kipfmueller, Thomas Schaible, Knoefel Wolfram Trudo, Christoph Mohr, Ramona Herwig, Max Samans, Reinhard Busse, Ulrike Nimptsch, Miriam Wilms |
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| 245 | 1 | 0 | |a Hospital volume and outcome in the treatment of congenital diaphragmatic hernia in Germany |b observational study using national hospital discharge data from 2016 to 2023 |c Julia Elrod, Michael Boettcher, Florian Kipfmueller, Thomas Schaible, Knoefel Wolfram Trudo, Christoph Mohr, Ramona Herwig, Max Samans, Reinhard Busse, Ulrike Nimptsch, Miriam Wilms |
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| 520 | |a Background - Congenital diaphragmatic hernia (CDH) is a critical malformation, with the neonatal period being particularly challenging and associated with high mortality. Data on the care structure and volume-outcome relationship in the treatment of children with CDH in Germany remain scarce. - Methods - This study determined case numbers and outcomes of treatment of children aged 0-17 years, with CDH in Germany between 2016 and 2023 through a query of the nationwide DRG database at the Research Data Center of the Federal Statistical Office. Using the ICD-10 and OPS codes, inpatient cases with and without ECMO treatment were identified. The analysis included patient characteristics, hospital caseload, treatment characteristics and outcome parameters stratified by hospital caseload. - Results - In the 8 years, a total of 1470 newborns with CDH were born across 234 different hospitals, with a median annual caseload of 1 (IQR: 1-2). In-hospital mortality was 22.5 %. Corrective surgery was performed in 1539 cases across 103 hospitals. Mortality among patients who underwent corrective surgery was 4.8 % in low-volume centers, 5.3 % in medium-volume centers, and 9.6 % in high-volume centers. A higher ECMO frequency was observed in high-volume centers (32.2 % vs. 5.4 % in medium-volume and 1.9 % in low-volume). Among all ECMO-treated CDH patients, regardless of corrective surgery, mortality was 60.0 %, 40.0 %, and 36.5 % in low-, medium-, and high-volume centers, respectively. - Conclusions - These findings indicate that high-volume centers treat a greater proportion of severe cases and that they may achieve better outcomes for the most critically ill patients, as reflected by lower ECMO-specific mortality. | ||
| 650 | 4 | |a Case load | |
| 650 | 4 | |a Congenital diaphragmatic hernia | |
| 650 | 4 | |a ECMO | |
| 650 | 4 | |a Mortality | |
| 650 | 4 | |a Volume-outcome | |
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| 700 | 1 | |a Mohr, Christoph |e VerfasserIn |4 aut | |
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| 700 | 1 | |a Wilms, Miriam |e VerfasserIn |4 aut | |
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