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The treatment of capsular contracture around breast implants induced by fractionated irradiation: the collagenase of the bacterium clostridium histolyticum as a novel therapeutic approach

Irradiation therapy limits the utilization of silicone implants for breast reconstruction due to a significant risk for capsular contracture. The injection of the collagenase of the bacterium Clostridium histolyticum (CCH) might trivialize this risk by providing a minimal-invasive treatment option b...

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Hauptverfasser: Diehm, Yannick (VerfasserIn) , Jost, Yanic (VerfasserIn) , Kotsougiani-Fischer, Dimitra (VerfasserIn) , Haug, Valentin (VerfasserIn) , Splinter, Mona (VerfasserIn) , Häring, Peter (VerfasserIn) , Berger, Martin R. (VerfasserIn) , Debus, Jürgen (VerfasserIn) , Kneser, Ulrich (VerfasserIn) , Fischer, Sebastian (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: June 2021
In: Aesthetic surgery journal
Year: 2021, Jahrgang: 45, Heft: 3, Pages: 1273-1281
ISSN:1527-330X
DOI:10.1007/s00266-020-01970-1
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00266-020-01970-1
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s00266-020-01970-1
Volltext
Verfasserangaben:Yannick F. Diehm, Yanic Jost, Dimitra Kotsougiani-Fischer, Valentin Haug, Mona Splinter, Peter Häring, Martin R. Berger, Jürgen Debus, Ulrich Kneser, Sebastian Fischer
Beschreibung
Zusammenfassung:Irradiation therapy limits the utilization of silicone implants for breast reconstruction due to a significant risk for capsular contracture. The injection of the collagenase of the bacterium Clostridium histolyticum (CCH) might trivialize this risk by providing a minimal-invasive treatment option by capsular contracture degradation. However, efficacy in degrading breast implant capsules induced by fractionated irradiation remains unclear.
Beschreibung:Online publiziert: 23. September 2020
Gesehen am 05.09.2025
Beschreibung:Online Resource
ISSN:1527-330X
DOI:10.1007/s00266-020-01970-1

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