The treatment of capsular contracture around breast implants induced by fractionated irradiation: the collagenase of the bacterium clostridium histolyticum as a novel therapeutic approach
Irradiation therapy limits the utilization of silicone implants for breast reconstruction due to a significant risk for capsular contracture. The injection of the collagenase of the bacterium Clostridium histolyticum (CCH) might trivialize this risk by providing a minimal-invasive treatment option b...
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| Hauptverfasser: | , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
June 2021
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| In: |
Aesthetic surgery journal
Year: 2021, Jahrgang: 45, Heft: 3, Pages: 1273-1281 |
| ISSN: | 1527-330X |
| DOI: | 10.1007/s00266-020-01970-1 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00266-020-01970-1 Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s00266-020-01970-1 
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| Verfasserangaben: | Yannick F. Diehm, Yanic Jost, Dimitra Kotsougiani-Fischer, Valentin Haug, Mona Splinter, Peter Häring, Martin R. Berger, Jürgen Debus, Ulrich Kneser, Sebastian Fischer |
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| 520 | |a Irradiation therapy limits the utilization of silicone implants for breast reconstruction due to a significant risk for capsular contracture. The injection of the collagenase of the bacterium Clostridium histolyticum (CCH) might trivialize this risk by providing a minimal-invasive treatment option by capsular contracture degradation. However, efficacy in degrading breast implant capsules induced by fractionated irradiation remains unclear. | ||
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