Calm in the chaos: Targeting mTOR to reduce glioma-driven neuronal hyperexcitability

Primary brain tumors induce neuronal hyperexcitability, leading to epileptic seizures. In this issue of Neuron, Goldberg et al.1 demonstrate genetic, structural, and functional alterations to excitatory tumor-associated neurons and how mTOR inhibition rapidly reverses these changes in a mouse model.

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Hauptverfasser: Karreman, Matthia A. (VerfasserIn) , Venkataramani, Varun (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 19 March 2025
In: Neuron
Year: 2025, Jahrgang: 113, Heft: 6, Pages: 795-797
ISSN:1097-4199
DOI:10.1016/j.neuron.2025.02.020
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.neuron.2025.02.020
Volltext
Verfasserangaben:Matthia A. Karreman and Varun Venkataramani

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