Efficacy of (68Ga)Ga-FAPI-PET as a non-invasive evaluation method of liver fibrosis: short communication
Liver fibrosis is a chronic fibrosing hepatic disorder following recurrent injury, characterized by the excessive accumulation of extracellular matrix. Early detection has a great clinical impact because 80-90% of hepatocellular carcinomas are known to develop in fibrotic or cirrhotic (end-stage fib...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
June 2025
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| In: |
Annals of nuclear medicine
Year: 2025, Jahrgang: 39, Heft: 6, Pages: 631-639 |
| ISSN: | 1864-6433 |
| DOI: | 10.1007/s12149-025-02027-6 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s12149-025-02027-6 Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s12149-025-02027-6 
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| Verfasserangaben: | Yuriko Mori, Katharina Tamburini, Emil Novruzov, Dominik Schmitt, Eleni Mavriopoulou, Sven H. Loosen, Christoph Roderburg, Tadashi Watabe, Clemens Kratochwil, Manuel Röhrich, Abass Alavi, Uwe Haberkorn, Frederik L. Giesel |
MARC
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| 245 | 1 | 0 | |a Efficacy of (68Ga)Ga-FAPI-PET as a non-invasive evaluation method of liver fibrosis |b short communication |c Yuriko Mori, Katharina Tamburini, Emil Novruzov, Dominik Schmitt, Eleni Mavriopoulou, Sven H. Loosen, Christoph Roderburg, Tadashi Watabe, Clemens Kratochwil, Manuel Röhrich, Abass Alavi, Uwe Haberkorn, Frederik L. Giesel |
| 246 | 1 | |i Abweichender Titel |a Efficacy of [68 Ga] Ga-FAPI-PET as a non-invasive evaluation method of liver fibrosis | |
| 246 | 3 | 3 | |a Efficacy of (68 Ga) Ga-FAPI-PET as a non-invasive evaluation method of liver fibrosis |
| 264 | 1 | |c June 2025 | |
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| 500 | |a Online verfügbar: 06. März 2025 | ||
| 500 | |a Gesehen am 12.09.2025 | ||
| 520 | |a Liver fibrosis is a chronic fibrosing hepatic disorder following recurrent injury, characterized by the excessive accumulation of extracellular matrix. Early detection has a great clinical impact because 80-90% of hepatocellular carcinomas are known to develop in fibrotic or cirrhotic (end-stage fibrotic) livers. PET imaging with FAP ligands exhibited highly promising results in recent years to visualize fibrosis in various organs due to the crucial role of activated fibroblasts in fibrosing processes. However, still little is known about the efficacy of FAP imaging in liver fibrosis. Thus, we sought to investigate the potential of FAPI-PET in a cohort of oncological and non-oncological patients. | ||
| 650 | 4 | |a FAPI | |
| 650 | 4 | |a Fibroblast activation protein | |
| 650 | 4 | |a Fibrosis | |
| 650 | 4 | |a Liver | |
| 650 | 4 | |a PET | |
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| 700 | 1 | |a Schmitt, Dominik |e VerfasserIn |4 aut | |
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| 700 | 1 | |a Roderburg, Christoph |e VerfasserIn |4 aut | |
| 700 | 1 | |a Watabe, Tadashi |e VerfasserIn |4 aut | |
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