Urine-derived renal tubular epithelial cells resemble functional characteristics of professional antigen-presenting cells and can directly induce BKV-specific T cell responses
Reactivation of the BK virus (BKV) is a critical adverse event after kidney transplantation and can lead to graft loss. BKV-reactive T cell-mediated viral control can be facilitated by reducing immunosuppression. However, the exact mechanism underlying the T cell-mediated BKV clearance in the kidney...
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| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
04 June 2025
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| In: |
Journal of nephrology
Year: 2025, Pages: 1-14 |
| ISSN: | 1724-6059 |
| DOI: | 10.1007/s40620-025-02298-2 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s40620-025-02298-2 Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s40620-025-02298-2 
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| Verfasserangaben: | Toralf Roch, Krystallenia Paniskaki, Patrizia Wehler, Constantin J. Thieme, Hanieh Moradian, Arturo Blazquez-Navarro, Moritz Anft, Petra Reinke, Timm H. Westhoff, Ulrik Stervbo, Nina Babel |
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| 520 | |a Reactivation of the BK virus (BKV) is a critical adverse event after kidney transplantation and can lead to graft loss. BKV-reactive T cell-mediated viral control can be facilitated by reducing immunosuppression. However, the exact mechanism underlying the T cell-mediated BKV clearance in the kidney transplant is not clear. | ||
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