Prediction of pathological complete response after neoadjuvant chemotherapy for HER2-negative breast cancer patients with routine immunohistochemical markers
Pathological complete response (pCR) is an established surrogate marker for prognosis in patients with breast cancer (BC) after neoadjuvant chemotherapy. Individualized pCR prediction based on clinical information available at biopsy, particularly immunohistochemical (IHC) markers, may help identify...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
24 January 2025
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| In: |
Breast cancer research
Year: 2025, Jahrgang: 27, Pages: 1-13 |
| ISSN: | 1465-542X |
| DOI: | 10.1186/s13058-025-01960-8 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13058-025-01960-8 Verlag, kostenfrei, Volltext: https://breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-025-01960-8 
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| Verfasserangaben: | Lothar Häberle, Ramona Erber, Paul Gass, Alexander Hein, Melitta Niklos, Bernhard Volz, Carolin C. Hack, Rüdiger Schulz-Wendtland, Hanna Huebner, Chloë Goossens, Matthias Christgen, Thilo Dörk, Tjoung-Won Park-Simon, Andreas Schneeweiss, Michael Untch, Valentina Nekljudova, Sibylle Loibl, Arndt Hartmann, Matthias W. Beckmann and Peter A. Fasching |
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| 245 | 1 | 0 | |a Prediction of pathological complete response after neoadjuvant chemotherapy for HER2-negative breast cancer patients with routine immunohistochemical markers |c Lothar Häberle, Ramona Erber, Paul Gass, Alexander Hein, Melitta Niklos, Bernhard Volz, Carolin C. Hack, Rüdiger Schulz-Wendtland, Hanna Huebner, Chloë Goossens, Matthias Christgen, Thilo Dörk, Tjoung-Won Park-Simon, Andreas Schneeweiss, Michael Untch, Valentina Nekljudova, Sibylle Loibl, Arndt Hartmann, Matthias W. Beckmann and Peter A. Fasching |
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| 520 | |a Pathological complete response (pCR) is an established surrogate marker for prognosis in patients with breast cancer (BC) after neoadjuvant chemotherapy. Individualized pCR prediction based on clinical information available at biopsy, particularly immunohistochemical (IHC) markers, may help identify patients who could benefit from preoperative chemotherapy. | ||
| 650 | 4 | |a Breast cancer | |
| 650 | 4 | |a Clinical data | |
| 650 | 4 | |a Immunohistochemistry | |
| 650 | 4 | |a Neoadjuvant chemotherapy | |
| 650 | 4 | |a pCR | |
| 650 | 4 | |a Prediction model | |
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| 700 | 1 | |a Gass, Paul |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hein, Alexander |e VerfasserIn |4 aut | |
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