Efficacy and safety of airway stent placement in the treatment of airway esophageal fistula
Introduction: This study aimed to evaluate both the clinical efficacy and safety of airway stent placement in the treatment of patients with esophageal cancer-associated airway esophageal fistula (AEF). The focus is on evaluating improvements in patient survival and quality of life. Methods: Overall...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
July 2025
|
| In: |
Respiration
Year: 2025, Jahrgang: 104, Heft: 7, Pages: 476-484 |
| ISSN: | 1423-0356 |
| DOI: | 10.1159/000544124 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1159/000544124
|
| Verfasserangaben: | Xiangnan Li, Peiyuan Luo, Mengyu Zhao, Feifei Wen, Guancheng Jiang, Yibei You, Yaru Liu, Xuan Wu, Felix J.F. Herth, Quncheng Zhang |
MARC
| LEADER | 00000naa a22000002c 4500 | ||
|---|---|---|---|
| 001 | 1937171345 | ||
| 003 | DE-627 | ||
| 005 | 20250929111947.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 250929s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1159/000544124 |2 doi | |
| 035 | |a (DE-627)1937171345 | ||
| 035 | |a (DE-599)KXP1937171345 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Li, Xiangnan |e VerfasserIn |0 (DE-588)1377722724 |0 (DE-627)1937172074 |4 aut | |
| 245 | 1 | 0 | |a Efficacy and safety of airway stent placement in the treatment of airway esophageal fistula |c Xiangnan Li, Peiyuan Luo, Mengyu Zhao, Feifei Wen, Guancheng Jiang, Yibei You, Yaru Liu, Xuan Wu, Felix J.F. Herth, Quncheng Zhang |
| 264 | 1 | |c July 2025 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Veröffentlicht: 17. Februar 2025 | ||
| 500 | |a Gesehen am 29.09.2025 | ||
| 520 | |a Introduction: This study aimed to evaluate both the clinical efficacy and safety of airway stent placement in the treatment of patients with esophageal cancer-associated airway esophageal fistula (AEF). The focus is on evaluating improvements in patient survival and quality of life. Methods: Overall, this study enrolled 111 patients diagnosed with esophageal cancer-associated AEF. Among them, 50 (45.0%) and 61 (55.0%) patients received airway stent placement and conservative treatment, respectively. Follow-up assessments were conducted to determine the clinical efficacy and safety of the interventions, with survival and quality of life as the primary endpoints. Results: By the end of the follow-up, 98 of 111 patients (88.3%) had died, leaving 13 survivors (11.7%). Patients with esophageal cancer-associated AEF had an overall mean survival time of 147.4 (95% CI, 123.9-170.9) days. Patients in the stent placement group had a mean survival of 192.5 (95% CI, 151.2-233.7) days, which was significantly longer than the 110.0 (95% CI, 88.1-131.8) days in the conservative treatment group (p < 0.001). Sex (p = 0.017), tumor stage (p = 0.030), surgery (p = 0.005), pulmonary infection (p < 0.001), fistula size (p < 0.001), and pre-Karnofsky Performance Status (KPS) (p < 0.001) were the independent risk factors affecting survival. Furthermore, patients in the stent placement group demonstrated improved KPS scores post-treatment, increasing from 48.2 to 57.9 (p = 0.017). Conclusion: Airway stent placement is beneficial in alleviating the symptoms, quality of life, and survival of patients with esophageal cancer-associated AEF. | ||
| 700 | 1 | |a Luo, Peiyuan |e VerfasserIn |4 aut | |
| 700 | 1 | |a Zhao, Mengyu |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wen, Feifei |e VerfasserIn |4 aut | |
| 700 | 1 | |a Jiang, Guancheng |e VerfasserIn |4 aut | |
| 700 | 1 | |a You, Yibei |e VerfasserIn |4 aut | |
| 700 | 1 | |a Liu, Yaru |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wu, Xuan |e VerfasserIn |4 aut | |
| 700 | 1 | |a Herth, Felix |e VerfasserIn |0 (DE-588)1016095236 |0 (DE-627)705477568 |0 (DE-576)351509925 |4 aut | |
| 700 | 1 | |a Zhang, Quncheng |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Respiration |d Basel : Karger, 1968 |g 104(2025), 7 vom: Juli, Seite 476-484 |h Online-Ressource |w (DE-627)26551035X |w (DE-600)1464419-8 |w (DE-576)112815111 |x 1423-0356 |7 nnas |a Efficacy and safety of airway stent placement in the treatment of airway esophageal fistula |
| 773 | 1 | 8 | |g volume:104 |g year:2025 |g number:7 |g month:07 |g pages:476-484 |g extent:9 |a Efficacy and safety of airway stent placement in the treatment of airway esophageal fistula |
| 856 | 4 | 0 | |u https://doi.org/10.1159/000544124 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20250929 | ||
| 993 | |a Article | ||
| 994 | |a 2025 | ||
| 998 | |g 1016095236 |a Herth, Felix |m 1016095236:Herth, Felix |d 910000 |d 950000 |d 950900 |d 50000 |e 910000PH1016095236 |e 950000PH1016095236 |e 950900PH1016095236 |e 50000PH1016095236 |k 0/910000/ |k 1/910000/950000/ |k 2/910000/950000/950900/ |k 0/50000/ |p 9 | ||
| 999 | |a KXP-PPN1937171345 |e 4777258599 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"id":{"doi":["10.1159/000544124"],"eki":["1937171345"]},"name":{"displayForm":["Xiangnan Li, Peiyuan Luo, Mengyu Zhao, Feifei Wen, Guancheng Jiang, Yibei You, Yaru Liu, Xuan Wu, Felix J.F. Herth, Quncheng Zhang"]},"note":["Veröffentlicht: 17. Februar 2025","Gesehen am 29.09.2025"],"language":["eng"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"title":[{"title":"Efficacy and safety of airway stent placement in the treatment of airway esophageal fistula","title_sort":"Efficacy and safety of airway stent placement in the treatment of airway esophageal fistula"}],"relHost":[{"recId":"26551035X","physDesc":[{"extent":"Online-Ressource"}],"disp":"Efficacy and safety of airway stent placement in the treatment of airway esophageal fistulaRespiration","origin":[{"dateIssuedKey":"1968","publisherPlace":"Basel","dateIssuedDisp":"1968-","publisher":"Karger"}],"pubHistory":["Vol. 25, no. 1 (1968)-"],"id":{"eki":["26551035X"],"issn":["1423-0356"],"zdb":["1464419-8"]},"title":[{"title_sort":"Respiration","title":"Respiration","subtitle":"international journal of thoracic medicine"}],"part":{"volume":"104","year":"2025","issue":"7","extent":"9","text":"104(2025), 7 vom: Juli, Seite 476-484","pages":"476-484"},"language":["eng"],"type":{"bibl":"periodical","media":"Online-Ressource"},"note":["Gesehen am 03.07.2024"]}],"person":[{"family":"Li","role":"aut","given":"Xiangnan","display":"Li, Xiangnan"},{"display":"Luo, Peiyuan","role":"aut","given":"Peiyuan","family":"Luo"},{"family":"Zhao","role":"aut","given":"Mengyu","display":"Zhao, Mengyu"},{"family":"Wen","role":"aut","given":"Feifei","display":"Wen, Feifei"},{"display":"Jiang, Guancheng","family":"Jiang","role":"aut","given":"Guancheng"},{"display":"You, Yibei","family":"You","given":"Yibei","role":"aut"},{"display":"Liu, Yaru","given":"Yaru","role":"aut","family":"Liu"},{"given":"Xuan","role":"aut","family":"Wu","display":"Wu, Xuan"},{"role":"aut","given":"Felix","family":"Herth","display":"Herth, Felix"},{"given":"Quncheng","role":"aut","family":"Zhang","display":"Zhang, Quncheng"}],"origin":[{"dateIssuedDisp":"July 2025","dateIssuedKey":"2025"}],"physDesc":[{"extent":"9 S."}],"recId":"1937171345"} | ||
| SRT | |a LIXIANGNANEFFICACYAN2025 | ||