Impact of adding aromatherapy to sound intervention on cardiovascular parameters and psychophysiological measures in cancer patients: a randomized exploratory trial
Introduction: Integrative therapeutic approaches are able to improve psychophysiological outcomes in cancer patients. Whether additional beneficial effects can be achieved by combining aromatherapy to sound intervention is unclear. Methods: Eighty cancer patients were randomized (1:1) to either a 20...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
November 2025
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| In: |
Oncology research and treatment
Year: 2025, Volume: 48, Issue: 11, Pages: 716-728 |
| ISSN: | 2296-5262 |
| DOI: | 10.1159/000545932 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1159/000545932 |
| Author Notes: | Anna Lena Hohneck, Melissa Troia, Valentin Kolar, Simone Weingärtner, Kirsten Merx, Felicitas Sarodnick, Athanasios Mavratzas, Iris Burkholder, Gerhard Schumacher, Wolf-Karsten Hofmann, Ralf-Dieter Hofheinz |
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| 520 | |a Introduction: Integrative therapeutic approaches are able to improve psychophysiological outcomes in cancer patients. Whether additional beneficial effects can be achieved by combining aromatherapy to sound intervention is unclear. Methods: Eighty cancer patients were randomized (1:1) to either a 20-min sound intervention (“sound only,” classical music via headphones) or a sound intervention combined with aromatherapy (“aroma”). Cardiovascular parameters (measured with VascAssist2.0), visual analogue scales for emotional well-being, anxiety, stress, pain and sadness, and the State Trait Anxiety Inventory were assessed before and after intervention. Results:Sound only led to a significant reduction in the heart rate, while a trend for a lower heart rate was observed in the aroma group. Both pulse wave velocity (p = 0.04) and vascular resistance (p = 0.04) were reduced by sound only. Psychophysiological outcomes were improved by both interventions with a more pronounced but not significantly different effect on pain reduction by aroma (aroma p < 0.001; sound only p = 0.002). Conclusion: Both interventions were able to improve psychophysiological outcomes. In terms of cardiovascular parameters, a sound intervention alone achieved greater but not significantly different results compared to aroma, while the addition of aromatherapy yielded no substantial additional effects. | ||
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