The evolution of gene regulation in mammalian cerebellum development
Gene regulatory changes are considered major drivers of evolutionary innovations, including the cerebellum’s expansion during human evolution, yet they remain largely unexplored. In this study, we combined single-nucleus measurements of gene expression and chromatin accessibility from six mammals (h...
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| Autori principali: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Natura: | Article (Journal) Chapter/Article |
| Lingua: | inglese |
| Pubblicazione: |
March 16, 2025
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| In: |
bioRxiv beta
Year: 2025, Pages: 1-67 |
| DOI: | 10.1101/2025.03.14.643248 |
| Accesso online: | Verlag, kostenfrei, Volltext: https://doi.org/10.1101/2025.03.14.643248 Verlag, kostenfrei, Volltext: https://www.biorxiv.org/content/10.1101/2025.03.14.643248v1 |
| Note sull'autore: | Ioannis Sarropoulos, Mari Sepp, Tetsuya Yamada, Philipp S.L. Schäfer, Nils Trost, Julia Schmidt, Céline Schneider, Charis Drummer, Sophie Mißbach, Ibrahim I. Taskiran, Nikolai Hecker, Carmen Bravo González-Blas, Niklas Kempynck, Robert Frömel, Piyush Joshi, Evgeny Leushkin, Frederik Arnskötter, Kevin Leiss, Konstantin Okonechnikov, Steven Lisgo, Miklós Palkovits, Svante Pääbo, Margarida Cardoso-Moreira, Lena M. Kutscher, Rüdiger Behr, Stefan M. Pfister, Stein Aerts and Henrik Kaessmann |
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