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Density and entropy of immune cells within the tumor microenvironment of primary tumors and matched brain metastases

Tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) have increasingly been reported to impact the brain metastatic process of solid tumors. However, data on intra-individual differences between primary tumor and brain metastasis (BM), as well as their correlation with clini...

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Bibliographische Detailangaben
Hauptverfasser: Kleinberger, Markus (VerfasserIn) , Cifci, Didem (VerfasserIn) , Paiato, Christina (VerfasserIn) , Tomasich, Erwin (VerfasserIn) , Mair, Maximilian (VerfasserIn) , Steindl, Ariane (VerfasserIn) , Spiró, Zoltán Péter (VerfasserIn) , Carrero, Zunamys I. (VerfasserIn) , Berchtold, Luzia (VerfasserIn) , Hainfellner, Johannes A. (VerfasserIn) , Müllauer, Leonhard (VerfasserIn) , Heller, Gerwin (VerfasserIn) , Preusser, Matthias (VerfasserIn) , Kather, Jakob Nikolas (VerfasserIn) , Bergmeister-Berghoff, Anna Sophie (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: Februar 2025
In: Acta Neuropathologica Communications
Year: 2025, Jahrgang: 13, Heft: 1, Pages: 1-12
ISSN:2051-5960
DOI:10.1186/s40478-025-01939-8
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s40478-025-01939-8
Volltext
Verfasserangaben:Markus Kleinberger, Didem Çifçi, Christina Paiato, Erwin Tomasich, Maximilian J. Mair, Ariane Steindl, Zoltán Spiró, Zunamys I. Carrero, Luzia Berchtold, Johannes Hainfellner, Leonhard Müllauer, Gerwin Heller, Matthias Preusser, Jakob Niklas Kather and Anna Sophie Berghoff
Beschreibung
Zusammenfassung:Tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) have increasingly been reported to impact the brain metastatic process of solid tumors. However, data on intra-individual differences between primary tumor and brain metastasis (BM), as well as their correlation with clinical outcome parameters, is scarce.
Beschreibung:Online veröffentlicht am 19. Februar 2025
Gesehen am 13.10.2025
Beschreibung:Online Resource
ISSN:2051-5960
DOI:10.1186/s40478-025-01939-8

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