Density and entropy of immune cells within the tumor microenvironment of primary tumors and matched brain metastases

Tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) have increasingly been reported to impact the brain metastatic process of solid tumors. However, data on intra-individual differences between primary tumor and brain metastasis (BM), as well as their correlation with clini...

Full description

Saved in:
Bibliographic Details
Main Authors: Kleinberger, Markus (Author) , Cifci, Didem (Author) , Paiato, Christina (Author) , Tomasich, Erwin (Author) , Mair, Maximilian (Author) , Steindl, Ariane (Author) , Spiró, Zoltán Péter (Author) , Carrero, Zunamys I. (Author) , Berchtold, Luzia (Author) , Hainfellner, Johannes A. (Author) , Müllauer, Leonhard (Author) , Heller, Gerwin (Author) , Preusser, Matthias (Author) , Kather, Jakob Nikolas (Author) , Bergmeister-Berghoff, Anna Sophie (Author)
Format: Article (Journal)
Language:English
Published: Februar 2025
In: Acta Neuropathologica Communications
Year: 2025, Volume: 13, Issue: 1, Pages: 1-12
ISSN:2051-5960
DOI:10.1186/s40478-025-01939-8
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s40478-025-01939-8
Get full text
Author Notes:Markus Kleinberger, Didem Çifçi, Christina Paiato, Erwin Tomasich, Maximilian J. Mair, Ariane Steindl, Zoltán Spiró, Zunamys I. Carrero, Luzia Berchtold, Johannes Hainfellner, Leonhard Müllauer, Gerwin Heller, Matthias Preusser, Jakob Niklas Kather and Anna Sophie Berghoff

MARC

LEADER 00000naa a2200000 c 4500
001 193827024X
003 DE-627
005 20251013100624.0
007 cr uuu---uuuuu
008 251013s2025 xx |||||o 00| ||eng c
024 7 |a 10.1186/s40478-025-01939-8  |2 doi 
035 |a (DE-627)193827024X 
035 |a (DE-599)KXP193827024X 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Kleinberger, Markus  |e VerfasserIn  |0 (DE-588)1378813995  |0 (DE-627)193827153X  |4 aut 
245 1 0 |a Density and entropy of immune cells within the tumor microenvironment of primary tumors and matched brain metastases  |c Markus Kleinberger, Didem Çifçi, Christina Paiato, Erwin Tomasich, Maximilian J. Mair, Ariane Steindl, Zoltán Spiró, Zunamys I. Carrero, Luzia Berchtold, Johannes Hainfellner, Leonhard Müllauer, Gerwin Heller, Matthias Preusser, Jakob Niklas Kather and Anna Sophie Berghoff 
264 1 |c Februar 2025 
300 |b Illustrationen 
300 |a 12 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Online veröffentlicht am 19. Februar 2025 
500 |a Gesehen am 13.10.2025 
520 |a Tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) have increasingly been reported to impact the brain metastatic process of solid tumors. However, data on intra-individual differences between primary tumor and brain metastasis (BM), as well as their correlation with clinical outcome parameters, is scarce. 
700 1 |a Cifci, Didem  |e VerfasserIn  |0 (DE-588)1290186758  |0 (DE-627)1845902726  |4 aut 
700 1 |a Paiato, Christina  |e VerfasserIn  |4 aut 
700 1 |a Tomasich, Erwin  |e VerfasserIn  |4 aut 
700 1 |a Mair, Maximilian  |d 1993-  |e VerfasserIn  |0 (DE-588)1269179993  |0 (DE-627)1817848364  |4 aut 
700 1 |a Steindl, Ariane  |e VerfasserIn  |4 aut 
700 1 |a Spiró, Zoltán Péter  |d 1987-  |e VerfasserIn  |0 (DE-588)1116560348  |0 (DE-627)871231824  |0 (DE-576)478498772  |4 aut 
700 1 |a Carrero, Zunamys I.  |e VerfasserIn  |4 aut 
700 1 |a Berchtold, Luzia  |e VerfasserIn  |4 aut 
700 1 |a Hainfellner, Johannes A.  |e VerfasserIn  |0 (DE-588)1327452502  |0 (DE-627)1886977860  |4 aut 
700 1 |a Müllauer, Leonhard  |d 1961-  |e VerfasserIn  |0 (DE-588)1310036365  |0 (DE-627)1870450019  |4 aut 
700 1 |a Heller, Gerwin  |e VerfasserIn  |4 aut 
700 1 |a Preusser, Matthias  |d 1976-  |e VerfasserIn  |0 (DE-588)1156333008  |0 (DE-627)1019103949  |0 (DE-576)502110627  |4 aut 
700 1 |a Kather, Jakob Nikolas  |d 1989-  |e VerfasserIn  |0 (DE-588)1064064914  |0 (DE-627)812897587  |0 (DE-576)423589091  |4 aut 
700 1 |a Bergmeister-Berghoff, Anna Sophie  |d 1987-  |e VerfasserIn  |0 (DE-588)1139308564  |0 (DE-627)897062426  |0 (DE-576)493233059  |4 aut 
773 0 8 |i Enthalten in  |t Acta Neuropathologica Communications  |d London : Biomed Central, 2013  |g 13(2025), 1, Artikel-ID 34, Seite 1-12  |h Online-Ressource  |w (DE-627)746066465  |w (DE-600)2715589-4  |w (DE-576)382284372  |x 2051-5960  |7 nnas  |a Density and entropy of immune cells within the tumor microenvironment of primary tumors and matched brain metastases 
773 1 8 |g volume:13  |g year:2025  |g number:1  |g elocationid:34  |g pages:1-12  |g extent:12  |a Density and entropy of immune cells within the tumor microenvironment of primary tumors and matched brain metastases 
856 4 0 |u https://doi.org/10.1186/s40478-025-01939-8  |x Verlag  |x Resolving-System  |z kostenfrei  |3 Volltext 
951 |a AR 
992 |a 20251013 
993 |a Article 
994 |a 2025 
998 |g 1064064914  |a Kather, Jakob Nikolas  |m 1064064914:Kather, Jakob Nikolas  |d 910000  |d 910100  |e 910000PK1064064914  |e 910100PK1064064914  |k 0/910000/  |k 1/910000/910100/  |p 14 
999 |a KXP-PPN193827024X  |e 478624306X 
BIB |a Y 
SER |a journal 
JSO |a {"name":{"displayForm":["Markus Kleinberger, Didem Çifçi, Christina Paiato, Erwin Tomasich, Maximilian J. Mair, Ariane Steindl, Zoltán Spiró, Zunamys I. Carrero, Luzia Berchtold, Johannes Hainfellner, Leonhard Müllauer, Gerwin Heller, Matthias Preusser, Jakob Niklas Kather and Anna Sophie Berghoff"]},"id":{"doi":["10.1186/s40478-025-01939-8"],"eki":["193827024X"]},"person":[{"display":"Kleinberger, Markus","family":"Kleinberger","given":"Markus","role":"aut"},{"role":"aut","given":"Didem","family":"Cifci","display":"Cifci, Didem"},{"display":"Paiato, Christina","family":"Paiato","role":"aut","given":"Christina"},{"family":"Tomasich","role":"aut","given":"Erwin","display":"Tomasich, Erwin"},{"display":"Mair, Maximilian","family":"Mair","role":"aut","given":"Maximilian"},{"given":"Ariane","role":"aut","family":"Steindl","display":"Steindl, Ariane"},{"given":"Zoltán Péter","role":"aut","family":"Spiró","display":"Spiró, Zoltán Péter"},{"family":"Carrero","role":"aut","given":"Zunamys I.","display":"Carrero, Zunamys I."},{"display":"Berchtold, Luzia","role":"aut","given":"Luzia","family":"Berchtold"},{"family":"Hainfellner","given":"Johannes A.","role":"aut","display":"Hainfellner, Johannes A."},{"family":"Müllauer","role":"aut","given":"Leonhard","display":"Müllauer, Leonhard"},{"role":"aut","given":"Gerwin","family":"Heller","display":"Heller, Gerwin"},{"family":"Preusser","role":"aut","given":"Matthias","display":"Preusser, Matthias"},{"family":"Kather","given":"Jakob Nikolas","role":"aut","display":"Kather, Jakob Nikolas"},{"given":"Anna Sophie","role":"aut","family":"Bergmeister-Berghoff","display":"Bergmeister-Berghoff, Anna Sophie"}],"relHost":[{"id":{"eki":["746066465"],"issn":["2051-5960"],"zdb":["2715589-4"]},"part":{"volume":"13","year":"2025","text":"13(2025), 1, Artikel-ID 34, Seite 1-12","extent":"12","issue":"1","pages":"1-12"},"title":[{"title":"Acta Neuropathologica Communications","title_sort":"Acta Neuropathologica Communications"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"language":["eng"],"note":["Gesehen am 29.11.18"],"origin":[{"dateIssuedKey":"2013","dateIssuedDisp":"2013-","publisherPlace":"London","publisher":"Biomed Central"}],"pubHistory":["1.2013 -"],"disp":"Density and entropy of immune cells within the tumor microenvironment of primary tumors and matched brain metastasesActa Neuropathologica Communications","recId":"746066465","physDesc":[{"extent":"Online-Ressource"}]}],"origin":[{"dateIssuedDisp":"Februar 2025","dateIssuedKey":"2025"}],"note":["Online veröffentlicht am 19. Februar 2025","Gesehen am 13.10.2025"],"language":["eng"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"title":[{"title_sort":"Density and entropy of immune cells within the tumor microenvironment of primary tumors and matched brain metastases","title":"Density and entropy of immune cells within the tumor microenvironment of primary tumors and matched brain metastases"}],"physDesc":[{"noteIll":"Illustrationen","extent":"12 S."}],"recId":"193827024X"} 
SRT |a KLEINBERGEDENSITYAND2025