Image analysis: 68Ga-FAPI-46 PET derived texture parameters improve the differentiation of malignant and benign pulmonary lesions

Pulmonary lesions inconclusive in 18F-FDG PET/CT are a known clinical problem. Both texture analysis and 68Ga-FAPI-46 have shown potential in thoracic oncological problems but their combination has not been assessed yet. This initial analysis aims to evaluate the utility of 68Ga-FAPI-46 PET texture...

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Hauptverfasser: Wessendorf, Joel (VerfasserIn) , Spektor, Anna-Maria (VerfasserIn) , Aboulmaouahib, Brahim (VerfasserIn) , Daum, Johanna (VerfasserIn) , Glatting, Frederik M. (VerfasserIn) , Schlamp, Kai (VerfasserIn) , Grott, Matthias (VerfasserIn) , Eichhorn, Florian (VerfasserIn) , Heußel, Claus Peter (VerfasserIn) , Kauczor, Hans-Ulrich (VerfasserIn) , Kreuter, Michael (VerfasserIn) , Schreckenberger, Mathias (VerfasserIn) , Winter, Hauke (VerfasserIn) , Haberkorn, Uwe (VerfasserIn) , Röhrich, Manuel (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 12 June 2025
In: Cancer imaging
Year: 2025, Jahrgang: 25, Heft: 1, Pages: 1-12
ISSN:1470-7330
DOI:10.1186/s40644-025-00886-w
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s40644-025-00886-w
Verlag, kostenfrei, Volltext: https://cancerimagingjournal.biomedcentral.com/articles/10.1186/s40644-025-00886-w
Volltext
Verfasserangaben:Joel Wessendorf, Anna-Maria Spektor, Brahim Aboulmaouahib, Johanna Daum, Frederik M. Glatting, Kai Schlamp, Matthias Grott, Florian Eichhorn, Claus Peter Heußel, Hans Ulrich Kauczor, Michael Kreuter, Mathias Schreckenberger, Hauke Winter, Uwe Haberkorn and Manuel Röhrich

MARC

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520 |a Pulmonary lesions inconclusive in 18F-FDG PET/CT are a known clinical problem. Both texture analysis and 68Ga-FAPI-46 have shown potential in thoracic oncological problems but their combination has not been assessed yet. This initial analysis aims to evaluate the utility of 68Ga-FAPI-46 PET texture parameters to differentiate between lung cancer and benign pulmonary lesions inconclusive in 18F-FDG PET/CT. 
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