Tranexamic acid in radical cystectomy: a systematic review and meta-analysis of efficacy and safety
Radical cystectomy (RC) is a high-risk procedure, associated with significant bleeding and high risk of perioperative blood transfusion (PBT), which may limit clinical and oncological outcomes. Tranexamic acid (TXA), an antifibrinolytic agent, effectively reduces bleeding in various surgical setting...
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| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
18 September 2025
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| In: |
World journal of urology
Year: 2025, Jahrgang: 43, Heft: 1, Pages: 1-10 |
| ISSN: | 1433-8726 |
| DOI: | 10.1007/s00345-025-05939-0 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00345-025-05939-0 Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00345-025-05939-0 
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| Verfasserangaben: | Maurin Helen Mangold, Victoria Luise Simone Wieland, Maurizio Grilli, Alexander Studier-Fischer, Caelán Max Haney-Aubert, Niklas Westhoff, Maurice Stephan Michel, Luisa Egen, Karl-Friedrich Kowalewski |
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| 520 | |a Radical cystectomy (RC) is a high-risk procedure, associated with significant bleeding and high risk of perioperative blood transfusion (PBT), which may limit clinical and oncological outcomes. Tranexamic acid (TXA), an antifibrinolytic agent, effectively reduces bleeding in various surgical settings; however, its role in RC remains understudied. This systematic review and meta-analysis evaluates the efficacy and safety of TXA in RC patients. | ||
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