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CBD attenuates amygdala response to negative emotional stimuli in individuals with alcohol use disorder: a randomized controlled trial

Negative affect is a key factor in Alcohol Use Disorder (AUD) associated with craving and relapse risk that is insufficiently treated by approved medications. Cannabidiol (CBD) has shown promising effects on negative affect, indicating its potential for addressing the neurocircuitry underlying negat...

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Bibliographic Details
Main Authors: Pfisterer, Marlen (Author) , Teetzmann, Anton (Author) , Vetter, Sina (Author) , Baeßler, Joscha (Author) , Schreckenberger, Lena (Author) , Zaiser, Judith (Author) , Stenger, Manuel (Author) , Bach, Patrick (Author)
Format: Article (Journal)
Language:English
Published: 29 August 2025
In: Psychopharmacology

ISSN:1432-2072
DOI:10.1007/s00213-025-06860-5
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00213-025-06860-5
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Author Notes:Marlen Pfisterer, Anton Teetzmann, Sina Vetter, Joscha Baeßler, Lena Schreckenberger, Judith Zaiser, Manuel Stenger, Patrick Bach
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Summary:Negative affect is a key factor in Alcohol Use Disorder (AUD) associated with craving and relapse risk that is insufficiently treated by approved medications. Cannabidiol (CBD) has shown promising effects on negative affect, indicating its potential for addressing the neurocircuitry underlying negative affect in AUD.
Item Description:Gesehen am 28.10.2025
Physical Description:Online Resource
ISSN:1432-2072
DOI:10.1007/s00213-025-06860-5

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