Prospective randomized study of stress and immune response after laparoscopic vs conventional colonic resection

Methods: In order to evaluate the stress and immunological response to laparoscopic and conventional colon resection we operated on male Wistar rats (350-380 g), performing either laparoscopic (n= 15) or open colon resection (n= 15). A third group (n= 10) underwent anesthesia only. Immediately befor...

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Main Authors: Kuntz, Christian (Author) , Wunsch, A. (Author) , Bay, Fatma (Author) , Windeler, Jürgen (Author) , Glaser, Florian (Author) , Herfarth, Christian (Author)
Format: Article (Journal)
Language:English
Published: 1998
In: Surgical endoscopy and other interventional techniques
Year: 1998, Volume: 12, Issue: 7, Pages: 963-967
ISSN:1432-2218
DOI:10.1007/s004649900757
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s004649900757
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Author Notes:C. Kuntz, A. Wunsch, F. Bay, J. Windeler, F. Glaser, C. Herfarth

MARC

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520 |a Methods: In order to evaluate the stress and immunological response to laparoscopic and conventional colon resection we operated on male Wistar rats (350-380 g), performing either laparoscopic (n= 15) or open colon resection (n= 15). A third group (n= 10) underwent anesthesia only. Immediately before and after surgery as well as 1 and 7 days postoperatively a 1 ml sample of blood was taken from the retrobulbar veinous plexus. Stress (corticosterone) and immune parameters (neopterin and interleukin [IL] 1-β) were measured. Furthermore, the body weight as a parameter of postoperative recovery was monitored. 
650 4 |a Key words: Laparoscopic colon resection — Stress parameter — Immune response — Postoperative recovery 
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