Higher risk of recurrence in partially thrombosed cerebral aneurysms post-WEB (Woven EndoBridge) device treatment: insights from the WorldWideWEB Consortium registry
Background - The Woven EndoBridge (WEB) device is a prevalent treatment for intracranial aneurysms. While many studies have assessed the obliteration rate post-WEB embolization, few have focused on long-term outcomes in partially thrombosed aneurysms. - - -...
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
29 April 2025
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| In: |
Journal of neuroInterventional surgery
Year: 2025, Pages: 1-8 |
| ISSN: | 1759-8486 |
| DOI: | 10.1136/jnis-2024-022628 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1136/jnis-2024-022628 Verlag, kostenfrei, Volltext: https://jnis.bmj.com/lookup/doi/10.1136/jnis-2024-022628 |
| Verfasserangaben: | Guillaume Saliou, Hamza Adel Salim, Basel Musmar, Nimer Adeeb, Assala Aslan, Christian Swaid, Miguel Cuellar, Mahmoud Dibas, Nicole M Cancelliere, Jose Danilo Bengzon Diestro, Oktay Algin, Sherief Ghozy, Sovann V Lay, Adrien Guenego, Leonardo Renieri, Joseph Anthony Carnevale, Panagiotis Mastorakos, Kareem ElNaamani, Eimad Shotar, Markus A Möhlenbruch, Michael Kral, Charlotte Chung, Mohamed M Salem, Ivan Lylyk, Paul M Foreman, Hamza Shaikh, Vedran Župančić, Muhammad Ubaid Hafeez, Joshua S Catapano, Muhammad Waqas, Muhammet Arslan, Onur Ergun, James D Rabinov, Yifan Ren, Clemens M Schirmer, Mariangela Piano, Anna Luisa Kuhn, Caterina Michelozzi, Robert M Starke, Ameer E Hassan, Mark Ogilvie, Anh Nguyen, Jesse Jones, Waleed Brinjikji, Marie Teresa Nawka, Marios-Nikos Psychogios, Christian Ulfert, Bryan Pukenas, Jan Karl Burkhardt, Thien J Huynh, Juan Carlos Martinez-Gutierrez, Muhammed Amir Essibayi, Sunil A Sheth, Diana Slawski, Rabih Tawk, Benjamin Pulli, Boris Lubicz, Pietro Panni, Ajit S Puri, Guglielmo Pero, Eytan Raz, Christoph J Griessenauer, Hamed Asadi, Adnan H Siddiqui, Elad I Levy, Neil Haranhalli, David Altschul, Andrew F Ducruet, Felipe C Albuquerque, Robert W Regenhardt, Christopher J Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Reddy Boddu, Jared Knopman, Stavropoula I Tjoumakaris, Hugo Cuellar, Pascal Jabbour, Frédéric Clarençon, Nicola Limbucci, Vitor M Pereira, Aman B Patel, Adam A Dmytriw, Steven D Hajdu |
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| 245 | 1 | 0 | |a Higher risk of recurrence in partially thrombosed cerebral aneurysms post-WEB (Woven EndoBridge) device treatment |b insights from the WorldWideWEB Consortium registry |c Guillaume Saliou, Hamza Adel Salim, Basel Musmar, Nimer Adeeb, Assala Aslan, Christian Swaid, Miguel Cuellar, Mahmoud Dibas, Nicole M Cancelliere, Jose Danilo Bengzon Diestro, Oktay Algin, Sherief Ghozy, Sovann V Lay, Adrien Guenego, Leonardo Renieri, Joseph Anthony Carnevale, Panagiotis Mastorakos, Kareem ElNaamani, Eimad Shotar, Markus A Möhlenbruch, Michael Kral, Charlotte Chung, Mohamed M Salem, Ivan Lylyk, Paul M Foreman, Hamza Shaikh, Vedran Župančić, Muhammad Ubaid Hafeez, Joshua S Catapano, Muhammad Waqas, Muhammet Arslan, Onur Ergun, James D Rabinov, Yifan Ren, Clemens M Schirmer, Mariangela Piano, Anna Luisa Kuhn, Caterina Michelozzi, Robert M Starke, Ameer E Hassan, Mark Ogilvie, Anh Nguyen, Jesse Jones, Waleed Brinjikji, Marie Teresa Nawka, Marios-Nikos Psychogios, Christian Ulfert, Bryan Pukenas, Jan Karl Burkhardt, Thien J Huynh, Juan Carlos Martinez-Gutierrez, Muhammed Amir Essibayi, Sunil A Sheth, Diana Slawski, Rabih Tawk, Benjamin Pulli, Boris Lubicz, Pietro Panni, Ajit S Puri, Guglielmo Pero, Eytan Raz, Christoph J Griessenauer, Hamed Asadi, Adnan H Siddiqui, Elad I Levy, Neil Haranhalli, David Altschul, Andrew F Ducruet, Felipe C Albuquerque, Robert W Regenhardt, Christopher J Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Reddy Boddu, Jared Knopman, Stavropoula I Tjoumakaris, Hugo Cuellar, Pascal Jabbour, Frédéric Clarençon, Nicola Limbucci, Vitor M Pereira, Aman B Patel, Adam A Dmytriw, Steven D Hajdu |
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| 520 | |a Background - The Woven EndoBridge (WEB) device is a prevalent treatment for intracranial aneurysms. While many studies have assessed the obliteration rate post-WEB embolization, few have focused on long-term outcomes in partially thrombosed aneurysms. - - - Objective - To assess whether partially thrombosed aneurysms are at higher risk of recurrence or retreatment following WEB embolization compared with non-thrombosed aneurysms. - - - Methods - We evaluated data from 22 academic institutions, focusing on previously untreated cerebral aneurysms treated with the WEB device. Logistic regression was utilized to analyze factors predicting long-term aneurysm obliteration and retreatment necessity. - - - Results - Among 1303 patients, 26 presented with a partially thrombosed aneurysm. In the partially thrombosed group, the mean aneurysm maximal diameter was 10.7±4 mm with a neck ratio of 1.99±1.19 mm, larger than in the control group where the mean aneurysm maximal diameter was 6.81±2.37 mm with a neck ratio of 1.64±0.51 mm (P<0.001 for both maximal diameter and neck ratio). At the final follow-up, partially thrombosed aneurysms treated by the WEB device had a 38.5% retreatment rate, compared with 7.0% for non-thrombosed aneurysms (P<0.001). Among partially thrombosed aneurysms, the Raymond-Roy type IIIa/b occlusion rate was higher (38.5% vs 9.9%, P<0.001). On multivariate analysis, partially thrombosed aneurysms compared with non-thrombosed aneurysms had an increased rate of retreatment (OR 3.64, 95% CI 1.28 to 10.1). - - - Conclusion - Partially thrombosed aneurysms are associated with a poorer occlusion rate and a higher rate of retreatment following WEB embolization. For partially thrombosed aneurysms, the WEB device appears suboptimal as a first-line treatment, and therefore alternative techniques should be prioritized. | ||
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| 700 | 1 | |a Rabinov, James D |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ren, Yifan |e VerfasserIn |4 aut | |
| 700 | 1 | |a Schirmer, Clemens M |e VerfasserIn |4 aut | |
| 700 | 1 | |a Piano, Mariangela |e VerfasserIn |4 aut | |
| 700 | 1 | |a Kuhn, Anna Luisa |e VerfasserIn |4 aut | |
| 700 | 1 | |a Michelozzi, Caterina |e VerfasserIn |4 aut | |
| 700 | 1 | |a Starke, Robert M |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hassan, Ameer E |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ogilvie, Mark |e VerfasserIn |4 aut | |
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| 700 | 1 | |a Brinjikji, Waleed |e VerfasserIn |4 aut | |
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