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Responsive population-based cohorts as platforms for characterising pathogen- and population-level infection dynamics for epidemic prevention, preparedness and response

Establishing population-based cohorts is indispensable for effective epidemic prevention, preparedness and response. Existing passive surveillance systems face limitations in their capacity to promptly provide representative data for estimating disease burden and modelling disease transmission. This...

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Hauptverfasser: Morales, Ivonne (VerfasserIn) , Nguyen, Van-Kinh (VerfasserIn) , Abd El Aziz, Mirna (VerfasserIn) , Sultanli, Ayten (VerfasserIn) , Bärnighausen, Till (VerfasserIn) , Becher, Heiko (VerfasserIn) , Ciesek, Sandra (VerfasserIn) , Kampmann, Beate (VerfasserIn) , Lange, Berit (VerfasserIn) , Rupp, Jan (VerfasserIn) , Scheithauer, Simone (VerfasserIn) , Ward, Helen (VerfasserIn) , Karch, André (VerfasserIn) , Denkinger, Claudia M. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 26 Jun 2025
In: Eurosurveillance
Year: 2025, Jahrgang: 30, Heft: 25, Pages: 1-8
ISSN:1560-7917
DOI:10.2807/1560-7917.ES.2025.30.25.2400255
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.2807/1560-7917.ES.2025.30.25.2400255
Verlag, kostenfrei, Volltext: https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.25.2400255
Volltext
Verfasserangaben:Ivonne Morales, Van Kính Nguyen, Mirna Abd El Aziz, Ayten Sultanli, Till Bärnighausen, Heiko Becher, Sandra Ciesek, Beate Kampmann, Berit Lange, Jan Rupp, Simone Scheithauer, Helen Ward, André Karch, Claudia M. Denkinger
Beschreibung
Zusammenfassung:Establishing population-based cohorts is indispensable for effective epidemic prevention, preparedness and response. Existing passive surveillance systems face limitations in their capacity to promptly provide representative data for estimating disease burden and modelling disease transmission. This perspective paper introduces a framework for establishing a dynamic and responsive nationally representative population-based cohort, with Germany as an example country. We emphasise the need for comprehensive demographic representation, innovative strategies to address participant attrition, efficient data collection and testing using digital tools, as well as novel data integration and analysis methods. Financial considerations and cost estimates for cohort establishment are discussed, highlighting potential cost savings through integration with existing research infrastructures and digital approaches. The framework outlined for creating, operating and integrating the cohort within the broader epidemiological landscape illustrates the potential of a population-based cohort to offer timely, evidence-based insights for robust public health interventions during both epidemics and pandemics, as well as during inter-epidemic periods.
Beschreibung:Gesehen am 10.11.2025
Beschreibung:Online Resource
ISSN:1560-7917
DOI:10.2807/1560-7917.ES.2025.30.25.2400255

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