Antiviral mechanisms and preclinical evaluation of amantadine analogs that continue to inhibit influenza A viruses with M2S31N-based drug resistance

To better manage seasonal and pandemic influenza infections, new drugs are needed with enhanced activity against amantadine- and rimantadine-resistant…

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Bibliographic Details
Main Authors:	Tietjen, Ian (Author) , Kwan, Daniel C. (Author) , Petrich, Annett (Author) , Zell, Roland (Author) , Antoniadou, Theodosia (Author) , Gavriilidou, Agni Faviola Mika (Author) , Tzitzoglaki, Christina (Author) , Rallis, Michail (Author) , Fedida, David (Author) , Sureda, Francesc X. (Author) , Mestdagh, Cato (Author) , Naesens, Lieve (Author) , Chiantia, Salvatore (Author) , Johnson, F. Brent (Author) , Kolocouris, Antonios (Author)
Format:	Article (Journal)
Language:	English
Published:	April 2025
In:	Antiviral research Year: 2025, Volume: 236, Pages: 1-11
ISSN:	1872-9096
DOI:	10.1016/j.antiviral.2025.106104
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.antiviral.2025.106104 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0166354225000300
Author Notes:	Ian Tietjen, Daniel C. Kwan, Annett Petrich, Roland Zell, Theodosia Antoniadou, Agni Gavriilidou, Christina Tzitzoglaki, Michail Rallis, David Fedida, Francesc X. Sureda, Cato Mestdagh, Lieve Naesens, Salvatore Chiantia, F. Brent Johnson, Antonios Kolocouris

Description
Summary:	To better manage seasonal and pandemic influenza infections, new drugs are needed with enhanced activity against amantadine- and rimantadine-resistant…
Item Description:	Im Titel ist "S31N" hochgestellt Online veröffentlicht: 11. Februar 2025, Artikelversion 17. Februar 2025 Gesehen am 11.11.2025
Physical Description:	Online Resource
ISSN:	1872-9096
DOI:	10.1016/j.antiviral.2025.106104