RANO criteria for response assessment of brain metastases based on amino acid PET imaging
Novel diagnostic and therapeutic opportunities are needed to improve medical care and outcome of patients with brain metastases, a frequent and severe complication of several cancer types. Currently, magnetic resonance imaging (MRI) is the primary method used for detection, treatment planning and di...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
08 May 2025
|
| In: |
Nature medicine
Year: 2025, Jahrgang: 31, Heft: 5, Pages: 1424-1430 |
| ISSN: | 1546-170X |
| DOI: | 10.1038/s41591-025-03633-7 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s41591-025-03633-7 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s41591-025-03633-7 
|
| Verfasserangaben: | Nathalie L. Albert, Norbert Galldiks, Benjamin M. Ellingson, Martin J. van den Bent, Susan M. Chang, Francesco Cicone, Eng-Siew Koh, Ian Law, Emilie Le Rhun, Maximilian J. Mair, Jan-Michael Werner, Anna S. Berghoff, Julia Furtner, Giuseppe Minniti, Andrew M. Scott, Susan C. Short, Jana Ivanidze, Derek R. Johnson, Bogdana Suchorska, Nelleke Tolboom, Joerg-Christian Tonn, Antoine Verger, Evanthia Galanis, Priscilla K. Brastianos, Patrick Y. Wen, Michael Weller, Nancy U. Lin & Matthias Preusser |
MARC
| LEADER | 00000naa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1941079164 | ||
| 003 | DE-627 | ||
| 005 | 20251113093210.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 251113s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1038/s41591-025-03633-7 |2 doi | |
| 035 | |a (DE-627)1941079164 | ||
| 035 | |a (DE-599)KXP1941079164 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Albert, Nathalie |e VerfasserIn |0 (DE-588)1334640998 |0 (DE-627)1893100537 |4 aut | |
| 245 | 1 | 0 | |a RANO criteria for response assessment of brain metastases based on amino acid PET imaging |c Nathalie L. Albert, Norbert Galldiks, Benjamin M. Ellingson, Martin J. van den Bent, Susan M. Chang, Francesco Cicone, Eng-Siew Koh, Ian Law, Emilie Le Rhun, Maximilian J. Mair, Jan-Michael Werner, Anna S. Berghoff, Julia Furtner, Giuseppe Minniti, Andrew M. Scott, Susan C. Short, Jana Ivanidze, Derek R. Johnson, Bogdana Suchorska, Nelleke Tolboom, Joerg-Christian Tonn, Antoine Verger, Evanthia Galanis, Priscilla K. Brastianos, Patrick Y. Wen, Michael Weller, Nancy U. Lin & Matthias Preusser |
| 264 | 1 | |c 08 May 2025 | |
| 300 | |b Illustrationen | ||
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 13.11.2025 | ||
| 520 | |a Novel diagnostic and therapeutic opportunities are needed to improve medical care and outcome of patients with brain metastases, a frequent and severe complication of several cancer types. Currently, magnetic resonance imaging (MRI) is the primary method used for detection, treatment planning and disease monitoring in patients with brain metastases, but this method has limitations. These limitations mean that MRI can inform on lesion size but cannot directly measure the activity or viability of tumor tissue. Positron emission tomography (PET) imaging, however, can visualize metabolically active tumor cells and is therefore increasingly incorporated into cancer care to assess tumor burden and response to treatment. Here, we define the PET Response Assessment in Neuro-Oncology (RANO) for brain metastasis (BM) 1.0 criteria for metabolic response assessment of brain metastases using amino acid PET. By introducing an innovative endpoint for next-generation clinical trials, the PET RANO BM 1.0 criteria aim to facilitate development of novel therapies for patients with brain metastases. | ||
| 650 | 4 | |a Cancer imaging | |
| 650 | 4 | |a CNS cancer | |
| 650 | 4 | |a Metastasis | |
| 700 | 1 | |a Galldiks, Norbert |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ellingson, Benjamin M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a van den Bent, Martin J. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Chang, Susan M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Cicone, Francesco |e VerfasserIn |4 aut | |
| 700 | 1 | |a Koh, Eng-Siew |e VerfasserIn |4 aut | |
| 700 | 1 | |a Law, Ian |e VerfasserIn |4 aut | |
| 700 | 1 | |a Le Rhun, Emilie |e VerfasserIn |4 aut | |
| 700 | 1 | |a Mair, Maximilian J. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Werner, Jan-Michael |e VerfasserIn |4 aut | |
| 700 | 1 | |a Berghoff, Anna S. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Furtner, Julia |e VerfasserIn |4 aut | |
| 700 | 1 | |a Minniti, Giuseppe |e VerfasserIn |4 aut | |
| 700 | 1 | |a Scott, Andrew M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Short, Susan C. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ivanidze, Jana |e VerfasserIn |4 aut | |
| 700 | 1 | |a Johnson, Derek R. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Suchorska, Bogdana |d 1983- |e VerfasserIn |0 (DE-588)140486887 |0 (DE-627)618899502 |0 (DE-576)318302624 |4 aut | |
| 700 | 1 | |a Tolboom, Nelleke |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tonn, Joerg-Christian |e VerfasserIn |4 aut | |
| 700 | 1 | |a Verger, Antoine |e VerfasserIn |4 aut | |
| 700 | 1 | |a Galanis, Evanthia |e VerfasserIn |4 aut | |
| 700 | 1 | |a Brastianos, Priscilla K. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wen, Patrick Y. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Weller, Michael |e VerfasserIn |4 aut | |
| 700 | 1 | |a Lin, Nancy U. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Preusser, Matthias |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Nature medicine |d [New York, NY] : Springer Nature, 1995 |g 31(2025), 5 vom: Mai, Seite 1424-1430 |h Online-Ressource |w (DE-627)301511640 |w (DE-600)1484517-9 |w (DE-576)288571274 |x 1546-170X |7 nnas |a RANO criteria for response assessment of brain metastases based on amino acid PET imaging |
| 773 | 1 | 8 | |g volume:31 |g year:2025 |g number:5 |g month:05 |g pages:1424-1430 |g extent:7 |a RANO criteria for response assessment of brain metastases based on amino acid PET imaging |
| 787 | 0 | 8 | |i Errata |a Albert, Nathalie |t Author Correction: RANO criteria for response assessment of brain metastases based on amino acid PET imaging |d 2025 |w (DE-627)1941080251 |
| 856 | 4 | 0 | |u https://doi.org/10.1038/s41591-025-03633-7 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.nature.com/articles/s41591-025-03633-7 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20251113 | ||
| 993 | |a Article | ||
| 994 | |a 2025 | ||
| 998 | |g 140486887 |a Suchorska, Bogdana |m 140486887:Suchorska, Bogdana |d 910000 |d 911200 |e 910000PS140486887 |e 911200PS140486887 |k 0/910000/ |k 1/910000/911200/ |p 19 | ||
| 999 | |a KXP-PPN1941079164 |e 4804331808 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"physDesc":[{"extent":"7 S.","noteIll":"Illustrationen"}],"id":{"eki":["1941079164"],"doi":["10.1038/s41591-025-03633-7"]},"relHost":[{"note":["Gesehen am 24. Juli 2018"],"id":{"issn":["1546-170X"],"zdb":["1484517-9"],"eki":["301511640"]},"physDesc":[{"extent":"Online-Ressource"}],"disp":"RANO criteria for response assessment of brain metastases based on amino acid PET imagingNature medicine","origin":[{"dateIssuedDisp":"2017-","publisher":"Springer Nature ; Nature America Inc.","dateIssuedKey":"2017","publisherPlace":"[New York, NY] ; New York, NY"}],"recId":"301511640","type":{"media":"Online-Ressource","bibl":"periodical"},"language":["eng"],"part":{"volume":"31","year":"2025","text":"31(2025), 5 vom: Mai, Seite 1424-1430","pages":"1424-1430","extent":"7","issue":"5"},"title":[{"title_sort":"Nature medicine","title":"Nature medicine"}],"pubHistory":["1.1995 -"]}],"note":["Gesehen am 13.11.2025"],"recId":"1941079164","origin":[{"dateIssuedDisp":"08 May 2025","dateIssuedKey":"2025"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"person":[{"family":"Albert","display":"Albert, Nathalie","given":"Nathalie","role":"aut"},{"role":"aut","given":"Norbert","display":"Galldiks, Norbert","family":"Galldiks"},{"family":"Ellingson","display":"Ellingson, Benjamin M.","role":"aut","given":"Benjamin M."},{"family":"van den Bent","display":"van den Bent, Martin J.","role":"aut","given":"Martin J."},{"display":"Chang, Susan M.","given":"Susan M.","role":"aut","family":"Chang"},{"family":"Cicone","display":"Cicone, Francesco","given":"Francesco","role":"aut"},{"display":"Koh, Eng-Siew","role":"aut","given":"Eng-Siew","family":"Koh"},{"family":"Law","display":"Law, Ian","given":"Ian","role":"aut"},{"family":"Le Rhun","display":"Le Rhun, Emilie","role":"aut","given":"Emilie"},{"family":"Mair","display":"Mair, Maximilian J.","role":"aut","given":"Maximilian J."},{"role":"aut","given":"Jan-Michael","display":"Werner, Jan-Michael","family":"Werner"},{"display":"Berghoff, Anna S.","role":"aut","given":"Anna S.","family":"Berghoff"},{"display":"Furtner, Julia","given":"Julia","role":"aut","family":"Furtner"},{"given":"Giuseppe","role":"aut","display":"Minniti, Giuseppe","family":"Minniti"},{"family":"Scott","role":"aut","given":"Andrew M.","display":"Scott, Andrew M."},{"role":"aut","given":"Susan C.","display":"Short, Susan C.","family":"Short"},{"family":"Ivanidze","display":"Ivanidze, Jana","given":"Jana","role":"aut"},{"role":"aut","given":"Derek R.","display":"Johnson, Derek R.","family":"Johnson"},{"display":"Suchorska, Bogdana","given":"Bogdana","role":"aut","family":"Suchorska"},{"family":"Tolboom","display":"Tolboom, Nelleke","given":"Nelleke","role":"aut"},{"display":"Tonn, Joerg-Christian","role":"aut","given":"Joerg-Christian","family":"Tonn"},{"display":"Verger, Antoine","role":"aut","given":"Antoine","family":"Verger"},{"display":"Galanis, Evanthia","given":"Evanthia","role":"aut","family":"Galanis"},{"family":"Brastianos","display":"Brastianos, Priscilla K.","role":"aut","given":"Priscilla K."},{"given":"Patrick Y.","role":"aut","display":"Wen, Patrick Y.","family":"Wen"},{"family":"Weller","display":"Weller, Michael","given":"Michael","role":"aut"},{"display":"Lin, Nancy U.","given":"Nancy U.","role":"aut","family":"Lin"},{"display":"Preusser, Matthias","role":"aut","given":"Matthias","family":"Preusser"}],"name":{"displayForm":["Nathalie L. Albert, Norbert Galldiks, Benjamin M. Ellingson, Martin J. van den Bent, Susan M. Chang, Francesco Cicone, Eng-Siew Koh, Ian Law, Emilie Le Rhun, Maximilian J. Mair, Jan-Michael Werner, Anna S. Berghoff, Julia Furtner, Giuseppe Minniti, Andrew M. Scott, Susan C. Short, Jana Ivanidze, Derek R. Johnson, Bogdana Suchorska, Nelleke Tolboom, Joerg-Christian Tonn, Antoine Verger, Evanthia Galanis, Priscilla K. Brastianos, Patrick Y. Wen, Michael Weller, Nancy U. Lin & Matthias Preusser"]},"title":[{"title":"RANO criteria for response assessment of brain metastases based on amino acid PET imaging","title_sort":"RANO criteria for response assessment of brain metastases based on amino acid PET imaging"}],"language":["eng"]} | ||
| SRT | |a ALBERTNATHRANOCRITER0820 | ||