Predictive criteria for overall survival and treatment duration of 2nd-line chemotherapy in patients with advanced pancreatic adenocarcinoma (AIO-PAK-0216): clinical studies

Not all patients with advanced pancreatic cancer (PC) profit from 2nd-line chemotherapy. We evaluated predictive factors that are routinely collected during clinical care with the aim to support an informed and shared decision.

Bibliographic Details

Main Authors:	Lutz, Manfred Paul (Author) , Ansorge, Nikolaus (Author) , Barmashenko, Gleb (Author) , Bauer, Hans (Author) , Burkart, Christof (Author) , Decker, Thomas (Author) , Ettrich, Thomas (Author) , Fischer von Weikersthal, Ludwig (Author) , Geer, Thomas (Author) , Gerhardt, Anke (Author) , Höfling, Sabine (Author) , Jacobasch, Lutz (Author) , Koenigsmann, Michael (Author) , Leidig, Tobias (Author) , Plentz, Ruben (Author) , Räth, Sebastian (Author) , Reichert, Dietmar (Author) , Schulte, Markos (Author) , Schulte, Nadine (Author) , Schwarzer, Andreas (Author) , Siegler, Gabriele (Author) , Waldschmidt, Dirk (Author) , Karthaus, Meinolf (Author)
Format:	Article (Journal)
Language:	English
Published:	14 October 2025
In:	British journal of cancer Year: 2025, Pages: 1-7
ISSN:	1532-1827
DOI:	10.1038/s41416-025-03188-x
Online Access:	Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41416-025-03188-x Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41416-025-03188-x
Author Notes:	Manfred P. Lutz, Nikolaus Ansorge, Gleb Barmashenko, Hans Bauer, Christof Burkart, Thomas Decker, Thomas Ettrich, Ludwig Fischer von Weikersthal, Thomas Geer, Anke Gerhardt, Sabine Höfling, Lutz Jacobasch, Michael Koenigsmann, Tobias Leidig, Ruben Plentz, Sebastian Räth, Dietmar Reichert, Markos Schulte, Nadine Schulte, Andreas Schwarzer, Gabriele Siegler, Dirk Waldschmidt and Meinolf Karthaus