Buchumschlag

Associations between patient-reported vision impairment in low luminance and vision-related quality of life in intermediate age-related macular degeneration

Intermediate age-related macular degeneration (iAMD) reduces vision under low-luminance conditions, affecting quality of life (QoL). The Vision Impairment in Low Luminance (VILL) questionnaire captures QoL domains relevant in iAMD but most AMD studies use the generic vision-related QoL measure Visua...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Terheyden, Jan H. (VerfasserIn) , Gittel, Lisa (VerfasserIn) , Wu, Zhichao (VerfasserIn) , Guymer, Robyn H. (VerfasserIn) , Finger, Robert P. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 26 September 2025
In: Scientific reports
Year: 2025, Jahrgang: 15, Pages: 1-7
ISSN:2045-2322
DOI:10.1038/s41598-025-21210-3
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41598-025-21210-3
Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41598-025-21210-3
Volltext
Verfasserangaben:Jan Henrik Terheyden, Lisa Gittel, Zhichao Wu, Robyn H. Guymer & Robert P. Finger

MARC

LEADER 00000caa a2200000 c 4500
001 1942478313
003 DE-627
005 20251126145830.0
007 cr uuu---uuuuu
008 251125s2025 xx |||||o 00| ||eng c
024 7 |a 10.1038/s41598-025-21210-3  |2 doi 
035 |a (DE-627)1942478313 
035 |a (DE-599)KXP1942478313 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Terheyden, Jan H.  |d 1991-  |e VerfasserIn  |0 (DE-588)1155799992  |0 (DE-627)1018201106  |0 (DE-576)501890114  |4 aut 
245 1 0 |a Associations between patient-reported vision impairment in low luminance and vision-related quality of life in intermediate age-related macular degeneration  |c Jan Henrik Terheyden, Lisa Gittel, Zhichao Wu, Robyn H. Guymer & Robert P. Finger 
264 1 |c 26 September 2025 
300 |b Illustrationen 
300 |a 7 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 25.11.2025 
520 |a Intermediate age-related macular degeneration (iAMD) reduces vision under low-luminance conditions, affecting quality of life (QoL). The Vision Impairment in Low Luminance (VILL) questionnaire captures QoL domains relevant in iAMD but most AMD studies use the generic vision-related QoL measure Visual Function Questionnaire (NEI VFQ). To investigate associations between these generic and specific vision-related QoL instruments, and explore the added value of including the VILL over the NEI VFQ in future iAMD studies, we analysed cross-sectional study data from individuals with iAMD. Associations were investigated using age-adjusted regression models. We included 150 participants (73% women, 74.6 ± 7.8 years). VILL subscale scores were associated with NEI VFQ scores (p ≤ 0.014) and explained 62.0% to 67.9% in the variance of the NEI VFQ scores. Ceiling effects were more common in the visual functioning NEI VFQ subscale than in the VILL-Reading subscale (p = 0.039), while the emotional well-being scores did not differ signficiantly between the instruments. NEI VFQ scores, VILL-Reading and VILL-Mobility subscale scores were associated with best-corrected visual acuity in either eye. Thus, assessments of vision-related QoL in iAMD using a generic instrument and a low luminance vision-specific instrument yield comparable but not identical results. The VILL has less ceiling effects than the NEI VFQ, suggesting its suitability for iAMD intervention trials and added value over the NEI VFQ in populations with few functional deficits. 
650 4 |a Eye manifestations 
650 4 |a Signs and symptoms 
700 1 |a Gittel, Lisa  |e VerfasserIn  |4 aut 
700 1 |a Wu, Zhichao  |e VerfasserIn  |4 aut 
700 1 |a Guymer, Robyn H.  |e VerfasserIn  |4 aut 
700 1 |a Finger, Robert P.  |d 1979-  |e VerfasserIn  |0 (DE-588)133279049  |0 (DE-627)539656488  |0 (DE-576)287511855  |4 aut 
773 0 8 |i Enthalten in  |t Scientific reports  |d [London] : Springer Nature, 2011  |g 15(2025), Artikel-ID 33317, Seite 1-7  |h Online-Ressource  |w (DE-627)663366712  |w (DE-600)2615211-3  |w (DE-576)346641179  |x 2045-2322  |7 nnas  |a Associations between patient-reported vision impairment in low luminance and vision-related quality of life in intermediate age-related macular degeneration 
773 1 8 |g volume:15  |g year:2025  |g elocationid:33317  |g pages:1-7  |g extent:7  |a Associations between patient-reported vision impairment in low luminance and vision-related quality of life in intermediate age-related macular degeneration 
856 4 0 |u https://doi.org/10.1038/s41598-025-21210-3  |x Verlag  |x Resolving-System  |z kostenfrei  |3 Volltext 
856 4 0 |u https://www.nature.com/articles/s41598-025-21210-3  |x Verlag  |z kostenfrei  |3 Volltext 
951 |a AR 
992 |a 20251125 
993 |a Article 
994 |a 2025 
998 |g 133279049  |a Finger, Robert P.  |m 133279049:Finger, Robert P.  |d 60000  |d 61700  |e 60000PF133279049  |e 61700PF133279049  |k 0/60000/  |k 1/60000/61700/  |p 5  |y j 
999 |a KXP-PPN1942478313  |e 4813461085 
BIB |a Y 
SER |a journal 
JSO |a {"type":{"media":"Online-Ressource","bibl":"article-journal"},"title":[{"title":"Associations between patient-reported vision impairment in low luminance and vision-related quality of life in intermediate age-related macular degeneration","title_sort":"Associations between patient-reported vision impairment in low luminance and vision-related quality of life in intermediate age-related macular degeneration"}],"note":["Gesehen am 25.11.2025"],"origin":[{"dateIssuedDisp":"26 September 2025","dateIssuedKey":"2025"}],"id":{"eki":["1942478313"],"doi":["10.1038/s41598-025-21210-3"]},"physDesc":[{"noteIll":"Illustrationen","extent":"7 S."}],"name":{"displayForm":["Jan Henrik Terheyden, Lisa Gittel, Zhichao Wu, Robyn H. Guymer & Robert P. Finger"]},"relHost":[{"part":{"extent":"7","text":"15(2025), Artikel-ID 33317, Seite 1-7","volume":"15","pages":"1-7","year":"2025"},"language":["eng"],"disp":"Associations between patient-reported vision impairment in low luminance and vision-related quality of life in intermediate age-related macular degenerationScientific reports","type":{"media":"Online-Ressource","bibl":"periodical"},"note":["Gesehen am 12.07.24"],"pubHistory":["1, article number 1 (2011)-"],"origin":[{"dateIssuedKey":"2011","publisher":"Springer Nature ; Nature Publishing Group","dateIssuedDisp":"2011-","publisherPlace":"[London] ; London"}],"title":[{"title":"Scientific reports","title_sort":"Scientific reports"}],"id":{"eki":["663366712"],"issn":["2045-2322"],"zdb":["2615211-3"]},"recId":"663366712","physDesc":[{"extent":"Online-Ressource"}]}],"recId":"1942478313","person":[{"family":"Terheyden","display":"Terheyden, Jan H.","given":"Jan H.","role":"aut"},{"role":"aut","given":"Lisa","display":"Gittel, Lisa","family":"Gittel"},{"display":"Wu, Zhichao","family":"Wu","role":"aut","given":"Zhichao"},{"role":"aut","given":"Robyn H.","display":"Guymer, Robyn H.","family":"Guymer"},{"display":"Finger, Robert P.","family":"Finger","given":"Robert P.","role":"aut"}],"language":["eng"]} 
SRT |a TERHEYDENJASSOCIATIO2620 

Ähnliche Einträge