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A genome resource for the marine annelid Platynereis spp

The marine annelid Platynereis dumerilii is a model organism used in many research areas including evolution and development, neurobiology, ecology and regeneration. Here we present the genomes of P. dumerilii (laboratory culture reference and a single individual assembly) and of the closely related...

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Hauptverfasser: Mutemi, Kevin Nzumbi (VerfasserIn) , Simakov, Oleg (VerfasserIn) , Pan, Leslie (VerfasserIn) , Santangeli, Luca (VerfasserIn) , Null, Ryan Wesley (VerfasserIn) , Handberg-Thorsager, Mette (VerfasserIn) , Vellutini, Bruno Cossermelli (VerfasserIn) , Peterson, Kevin J. (VerfasserIn) , Fromm, Bastian (VerfasserIn) , Larsson, Tomas (VerfasserIn) , Savage, Emily (VerfasserIn) , Lopez, Mireia Osuna (VerfasserIn) , Hercog, Rajna (VerfasserIn) , Provaznik, Jan (VerfasserIn) , Ordoñez-Rueda, Diana (VerfasserIn) , Azevedo, Nayara (VerfasserIn) , Gazave, Eve (VerfasserIn) , Vervoort, Michel (VerfasserIn) , Tomancak, Pavel (VerfasserIn) , Tan, Wenhua (VerfasserIn) , Winkler, Sylke (VerfasserIn) , Benes, Vladimir (VerfasserIn) , Hui, Jerome (VerfasserIn) , Helm, Conrad (VerfasserIn) , Özpolat, B. Duygu (VerfasserIn) , Arendt, Detlev (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 14 July 2025
In: BMC genomics
Year: 2025, Jahrgang: 26, Pages: 1-27
ISSN:1471-2164
DOI:10.1186/s12864-025-11727-2
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12864-025-11727-2
Volltext
Verfasserangaben:Kevin Nzumbi Mutemi, Oleg Simakov, Leslie Pan, Luca Santangeli, Ryan Wesley Null, Mette Handberg-Thorsager, Bruno Cossermelli Vellutini, Kevin J. Peterson, Bastian Fromm, Tomas Larsson, Emily Savage, Mireia Osuna Lopez, Rajna Hercog, Jan Provaznik, Diana Ordoñez-Rueda, Nayara Azevedo, Eve Gazave, Michel Vervoort, Pavel Tomancak, Wenhua Tan, Sylke Winkler, Vladimir Benes, Jerome Hui, Conrad Helm, B. Duygu Özpolat and Detlev Arendt
Beschreibung
Zusammenfassung:The marine annelid Platynereis dumerilii is a model organism used in many research areas including evolution and development, neurobiology, ecology and regeneration. Here we present the genomes of P. dumerilii (laboratory culture reference and a single individual assembly) and of the closely related P. massiliensis and P. megalops (single individual assembly) to facilitate comparative genomic approaches and help explore Platynereis biology. We used long-read sequencing technology and chromosomal-conformation capture along with extensive transcriptomic resources to obtain and annotate a draft genome assembly of ~ 1.47 Gbp for P. dumerilii, of which more than half represent repeat elements. We predict around 29,000 protein-coding genes, with relatively large intron sizes, over 38,000 non-coding genes, and 105 miRNA loci. We further explore the high genetic variation (~ 3% heterozygosity) within the Platynereis species complex. Gene ontology reveals the most variable loci to be associated with pigmentation, development and immunity. The current work sets the stage for further development of Platynereis genomic resources.
Beschreibung:Veröffentlicht: 14. Juli 2025
Gesehen am 26.11.2025
Beschreibung:Online Resource
ISSN:1471-2164
DOI:10.1186/s12864-025-11727-2

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