Defining ideal middle cerebral artery bifurcation aneurysm size for Woven EndoBridge embolization
OBJECTIVE The Woven EndoBridge (WEB) device was approved to treat wide-necked bifurcation aneurysms. The device is designed as an intrasaccular flow disruptor covering aneurysm widths up to 10 mm. Although prior studies combined all aneurysm sizes, it is known that aneurysms behave differently in re...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
March 2025
|
| In: |
Journal of neurosurgery
Year: 2024, Jahrgang: 142, Heft: 3, Pages: 647-657 |
| ISSN: | 1933-0693 |
| DOI: | 10.3171/2024.5.JNS232204 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3171/2024.5.JNS232204 Verlag, lizenzpflichtig, Volltext: https://thejns.org/view/journals/j-neurosurg/142/3/article-p647.xml 
|
| Verfasserangaben: | Nimer Adeeb, Basel Musmar, Hamza Adel Salim, Assala Aslan, Anika Alla, Nicole M. Cancelliere, Rachel M. McLellan, Oktay Algin, Sherief Ghozy, Mahmoud Dibas, Sovann V. Lay, Adrien Guenego, Leonardo Renieri, Joseph Carnevale, Guillaume Saliou, Panagiotis Mastorakos, Kareem El Naamani, Eimad Shotar, Kevin Premat, Markus Möhlenbruch, Michael Kral, Omer Doron, Charlotte Chung, Mohamed M. Salem, Ivan Lylyk, Paul M. Foreman, Jay A. Vachhani, Hamza Shaikh, Vedran Župančić, Muhammad U. Hafeez, Joshua S. Catapano, Muhammad Waqas, Vincent M. Tutino, Mohamed K. Ibrahim, Marwa A. Mohammed, M. Ozgur Ozates, Giyas Ayberk, James D. Rabinov, Yifan Ren, Clemens M. Schirmer, Mariangela Piano, Anna L. Kühn, Caterina Michelozzi, Stéphanie Elens, Robert M. Starke, Ameer Hassan, Mark Ogilvie, Anh Nguyen, Jesse Jones, Waleed Brinjikji, Marie T. Nawka, Marios Psychogios, Christian Ulfert, Jose Danilo Bengzon Diestro, Bryan Pukenas, Jan-Karl Burkhardt, Ricardo A. Domingo, Thien Huynh, Juan Carlos Martinez-Gutierrez, Muhammed Amir Essibayi, Sunil A. Sheth, Gary Spiegel, Rabih G. Tawk, Boris Lubicz, Pietro Panni, Ajit S. Puri, Guglielmo Pero, Erez Nossek, Eytan Raz, Monika Killer-Oberfalzer, Christoph J. Griessenauer, Hamed Asadi, Adnan Siddiqui, Allan L. Brook, David Altschul, Andrew F. Ducruet, Felipe C. Albuquerque, Robert W. Regenhardt, Christopher J. Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Mohammad A. Aziz-Sultan, Stavropoula I. Tjoumakaris, Frédéric Clarençon, Nicola Limbucci, Hugo H. Cuellar-Saenz, Pascal M. Jabbour, Vitor Mendes Pereira, Aman B. Patel, and Adam A. Dmytriw |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1942616430 | ||
| 003 | DE-627 | ||
| 005 | 20260112090523.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 251126s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3171/2024.5.JNS232204 |2 doi | |
| 035 | |a (DE-627)1942616430 | ||
| 035 | |a (DE-599)KXP1942616430 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Adeeb, Nimer |e VerfasserIn |0 (DE-588)1282578626 |0 (DE-627)1838223304 |4 aut | |
| 245 | 1 | 0 | |a Defining ideal middle cerebral artery bifurcation aneurysm size for Woven EndoBridge embolization |c Nimer Adeeb, Basel Musmar, Hamza Adel Salim, Assala Aslan, Anika Alla, Nicole M. Cancelliere, Rachel M. McLellan, Oktay Algin, Sherief Ghozy, Mahmoud Dibas, Sovann V. Lay, Adrien Guenego, Leonardo Renieri, Joseph Carnevale, Guillaume Saliou, Panagiotis Mastorakos, Kareem El Naamani, Eimad Shotar, Kevin Premat, Markus Möhlenbruch, Michael Kral, Omer Doron, Charlotte Chung, Mohamed M. Salem, Ivan Lylyk, Paul M. Foreman, Jay A. Vachhani, Hamza Shaikh, Vedran Župančić, Muhammad U. Hafeez, Joshua S. Catapano, Muhammad Waqas, Vincent M. Tutino, Mohamed K. Ibrahim, Marwa A. Mohammed, M. Ozgur Ozates, Giyas Ayberk, James D. Rabinov, Yifan Ren, Clemens M. Schirmer, Mariangela Piano, Anna L. Kühn, Caterina Michelozzi, Stéphanie Elens, Robert M. Starke, Ameer Hassan, Mark Ogilvie, Anh Nguyen, Jesse Jones, Waleed Brinjikji, Marie T. Nawka, Marios Psychogios, Christian Ulfert, Jose Danilo Bengzon Diestro, Bryan Pukenas, Jan-Karl Burkhardt, Ricardo A. Domingo, Thien Huynh, Juan Carlos Martinez-Gutierrez, Muhammed Amir Essibayi, Sunil A. Sheth, Gary Spiegel, Rabih G. Tawk, Boris Lubicz, Pietro Panni, Ajit S. Puri, Guglielmo Pero, Erez Nossek, Eytan Raz, Monika Killer-Oberfalzer, Christoph J. Griessenauer, Hamed Asadi, Adnan Siddiqui, Allan L. Brook, David Altschul, Andrew F. Ducruet, Felipe C. Albuquerque, Robert W. Regenhardt, Christopher J. Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Mohammad A. Aziz-Sultan, Stavropoula I. Tjoumakaris, Frédéric Clarençon, Nicola Limbucci, Hugo H. Cuellar-Saenz, Pascal M. Jabbour, Vitor Mendes Pereira, Aman B. Patel, and Adam A. Dmytriw |
| 264 | 1 | |c March 2025 | |
| 300 | |b Diagramme | ||
| 300 | |a 11 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Online veröffentlicht: 11. Oktober 2024 | ||
| 500 | |a Gesehen am 26.11.2025 | ||
| 520 | |a OBJECTIVE The Woven EndoBridge (WEB) device was approved to treat wide-necked bifurcation aneurysms. The device is designed as an intrasaccular flow disruptor covering aneurysm widths up to 10 mm. Although prior studies combined all aneurysm sizes, it is known that aneurysms behave differently in response to endovascular treatment based on their size. Therefore, the authors’ objective was to identify ideal middle cerebral artery (MCA) aneurysm width and neck sizes most suitable for WEB treatment. METHODS The WorldWideWEB consortium is a large multicenter retrospective database that analyzes intracranial aneurysms treated with the WEB device. In this study, all unruptured MCA bifurcation aneurysms with available measurements were included. Cutoff values based on aneurysm width and neck in relation to aneurysm occlusion status were measured using the receiver operating characteristic (ROC) curve. Propensity score matching (PSM) was then used to compare treatment outcomes between aneurysms smaller and larger than the cutoff value for both width and neck size. RESULTS The ideal cutoff values for MCA bifurcation aneurysm width and neck were 6.1 mm and 4.6 mm, respectively. On PSM, 87 matched pairs were compared based on width size (≤ 6.1 mm and > 6.1 mm), and 77 matched pairs were compared based on neck size (≤ 4.6 mm and > 4.6 mm). There was a significant difference in adequate aneurysm occlusion between aneurysms smaller and larger than those cutoff values for both widths (93% vs 76%, p = 0.0017) and neck sizes (90% vs 70%, p = 0.0026). The retreatment rate was also significantly higher for larger aneurysms in both parameters. CONCLUSIONS This study shows that MCA bifurcation aneurysms ≤ 6.1 mm in width and ≤ 4.6 mm in neck size are significantly better candidates for WEB treatment, leading to improved occlusion status and reduced retreatment rate, which are important considerations when using WEB devices. | ||
| 650 | 4 | |a aneurysms | |
| 650 | 4 | |a intracranial | |
| 650 | 4 | |a vascular disorders | |
| 650 | 4 | |a WEB | |
| 650 | 4 | |a Woven EndoBridge | |
| 700 | 1 | |a Möhlenbruch, Markus Alfred |d 1979- |e VerfasserIn |0 (DE-588)137693591 |0 (DE-627)594845041 |0 (DE-576)304845655 |4 aut | |
| 700 | 1 | |a Ulfert, Christian |e VerfasserIn |0 (DE-588)1160254486 |0 (DE-627)1023399040 |0 (DE-576)505801094 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of neurosurgery |d Charlottesville, Va. : American Assoc. of Neurological Surgeons, 1944 |g 142(2024), 3, Seite 647-657 |h Online-Ressource |w (DE-627)323605737 |w (DE-600)2026156-1 |w (DE-576)09388866X |x 1933-0693 |7 nnas |a Defining ideal middle cerebral artery bifurcation aneurysm size for Woven EndoBridge embolization |
| 773 | 1 | 8 | |g volume:142 |g year:2024 |g number:3 |g pages:647-657 |g extent:11 |a Defining ideal middle cerebral artery bifurcation aneurysm size for Woven EndoBridge embolization |
| 856 | 4 | 0 | |u https://doi.org/10.3171/2024.5.JNS232204 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |7 1 |
| 856 | 4 | 0 | |u https://thejns.org/view/journals/j-neurosurg/142/3/article-p647.xml |x Verlag |z lizenzpflichtig |3 Volltext |7 1 |
| 951 | |a AR | ||
| 992 | |a 20251126 | ||
| 993 | |a Article | ||
| 994 | |a 2025 | ||
| 998 | |g 1160254486 |a Ulfert, Christian |m 1160254486:Ulfert, Christian |d 50000 |e 50000PU1160254486 |k 0/50000/ |p 53 | ||
| 998 | |g 137693591 |a Möhlenbruch, Markus Alfred |m 137693591:Möhlenbruch, Markus Alfred |d 910000 |d 911100 |d 50000 |e 910000PM137693591 |e 911100PM137693591 |e 50000PM137693591 |k 0/910000/ |k 1/910000/911100/ |k 0/50000/ |p 20 | ||
| 999 | |a KXP-PPN1942616430 |e 4814310641 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"language":["eng"],"name":{"displayForm":["Nimer Adeeb, Basel Musmar, Hamza Adel Salim, Assala Aslan, Anika Alla, Nicole M. Cancelliere, Rachel M. McLellan, Oktay Algin, Sherief Ghozy, Mahmoud Dibas, Sovann V. Lay, Adrien Guenego, Leonardo Renieri, Joseph Carnevale, Guillaume Saliou, Panagiotis Mastorakos, Kareem El Naamani, Eimad Shotar, Kevin Premat, Markus Möhlenbruch, Michael Kral, Omer Doron, Charlotte Chung, Mohamed M. Salem, Ivan Lylyk, Paul M. Foreman, Jay A. Vachhani, Hamza Shaikh, Vedran Župančić, Muhammad U. Hafeez, Joshua S. Catapano, Muhammad Waqas, Vincent M. Tutino, Mohamed K. Ibrahim, Marwa A. Mohammed, M. Ozgur Ozates, Giyas Ayberk, James D. Rabinov, Yifan Ren, Clemens M. Schirmer, Mariangela Piano, Anna L. Kühn, Caterina Michelozzi, Stéphanie Elens, Robert M. Starke, Ameer Hassan, Mark Ogilvie, Anh Nguyen, Jesse Jones, Waleed Brinjikji, Marie T. Nawka, Marios Psychogios, Christian Ulfert, Jose Danilo Bengzon Diestro, Bryan Pukenas, Jan-Karl Burkhardt, Ricardo A. Domingo, Thien Huynh, Juan Carlos Martinez-Gutierrez, Muhammed Amir Essibayi, Sunil A. Sheth, Gary Spiegel, Rabih G. Tawk, Boris Lubicz, Pietro Panni, Ajit S. Puri, Guglielmo Pero, Erez Nossek, Eytan Raz, Monika Killer-Oberfalzer, Christoph J. Griessenauer, Hamed Asadi, Adnan Siddiqui, Allan L. Brook, David Altschul, Andrew F. Ducruet, Felipe C. Albuquerque, Robert W. Regenhardt, Christopher J. Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Mohammad A. Aziz-Sultan, Stavropoula I. Tjoumakaris, Frédéric Clarençon, Nicola Limbucci, Hugo H. Cuellar-Saenz, Pascal M. Jabbour, Vitor Mendes Pereira, Aman B. Patel, and Adam A. Dmytriw"]},"person":[{"given":"Nimer","display":"Adeeb, Nimer","role":"aut","family":"Adeeb"},{"display":"Möhlenbruch, Markus Alfred","given":"Markus Alfred","role":"aut","family":"Möhlenbruch"},{"display":"Ulfert, Christian","given":"Christian","role":"aut","family":"Ulfert"}],"recId":"1942616430","note":["Online veröffentlicht: 11. Oktober 2024","Gesehen am 26.11.2025"],"title":[{"title":"Defining ideal middle cerebral artery bifurcation aneurysm size for Woven EndoBridge embolization","title_sort":"Defining ideal middle cerebral artery bifurcation aneurysm size for Woven EndoBridge embolization"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"id":{"eki":["1942616430"],"doi":["10.3171/2024.5.JNS232204"]},"physDesc":[{"extent":"11 S.","noteIll":"Diagramme"}],"relHost":[{"corporate":[{"role":"isb","display":"American Association of Neurological Surgeons"}],"disp":"Defining ideal middle cerebral artery bifurcation aneurysm size for Woven EndoBridge embolizationJournal of neurosurgery","type":{"bibl":"periodical","media":"Online-Ressource"},"titleAlt":[{"title":"Spine"},{"title":"Pediatrics"},{"title":"JNS"}],"language":["eng"],"part":{"volume":"142","year":"2024","text":"142(2024), 3, Seite 647-657","extent":"11","pages":"647-657","issue":"3"},"pubHistory":["1.1944 -"],"note":["Gesehen am 04.08.25","Ungezählte Beil. 1999-2004,Jun : Spine; 2004-2007: Pediatrics"],"title":[{"subtitle":"JNS","title":"Journal of neurosurgery","title_sort":"Journal of neurosurgery"}],"id":{"issn":["1933-0693"],"eki":["323605737"],"zdb":["2026156-1"]},"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"publisherPlace":"Charlottesville, Va.","dateIssuedKey":"1944","dateIssuedDisp":"1944-","publisher":"American Assoc. of Neurological Surgeons"}],"name":{"displayForm":["American Association of Neurological Surgeons"]},"recId":"323605737"}],"origin":[{"dateIssuedDisp":"March 2025","dateIssuedKey":"2025"}]} | ||
| SRT | |a ADEEBNIMERDEFININGID2025 | ||