Safety and effectiveness of cholecystectomy and endoscopic retrograde cholangiopancreatography in biliary pancreatitis during pregnancy: BORN study
Background Biliary acute pancreatitis (AP) during pregnancy is a challenging situation, and current guidelines for AP, pregnancy care, and surgery do not specifically address its management. This study investigated the safety and effectiveness of cholecystectomy and endoscopic retrograde cholangiopa...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
November 2025
|
| In: |
United european gastroenterology journal
Year: 2025, Jahrgang: 13, Heft: 9, Pages: 1803-1811 |
| ISSN: | 2050-6414 |
| DOI: | 10.1002/ueg2.70121 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1002/ueg2.70121 Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/ueg2.70121 
|
| Verfasserangaben: | Dorottya Tarján, Eszter Ágnes Szalai, Bálint Erőss, Péter Jenő Hegyi, Vasile Liviu Drug, Serge Chooklin, Michael Hirth, Gabriel Sandblom, Vanessa Sandblom, Åsa Edergren, Ahmed Tlili, Sami Fendri, Simon Sirtl, Daniel de la Iglesia Gracía, Floreta Kurti, Dong Wu, Adriana Gherbon, Łukasz Nawacki, Alexandru Constantinescu, Natalia V. Shirinskaya, Alexander N. Zolotov, Sanjay Pandanaboyana, Tsukasa Ikeura, Tiago Cúrdia Gonçalves, Louise Rasmussen, Bodil Andersson, Ahmed Bouzid, Ahmed Saidani, Nándor Ács, Zoltán Sipos, Nelli Farkas, Balázs Tihanyi, Brigitta Teutsch, Johan Nilsson, Alexandra Mikó, Péter Hegyi |
MARC
| LEADER | 00000naa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1942674198 | ||
| 003 | DE-627 | ||
| 005 | 20251127084806.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 251127s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1002/ueg2.70121 |2 doi | |
| 035 | |a (DE-627)1942674198 | ||
| 035 | |a (DE-599)KXP1942674198 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Tarján, Dorottya |e VerfasserIn |0 (DE-588)1382803346 |0 (DE-627)1942674546 |4 aut | |
| 245 | 1 | 0 | |a Safety and effectiveness of cholecystectomy and endoscopic retrograde cholangiopancreatography in biliary pancreatitis during pregnancy |b BORN study |c Dorottya Tarján, Eszter Ágnes Szalai, Bálint Erőss, Péter Jenő Hegyi, Vasile Liviu Drug, Serge Chooklin, Michael Hirth, Gabriel Sandblom, Vanessa Sandblom, Åsa Edergren, Ahmed Tlili, Sami Fendri, Simon Sirtl, Daniel de la Iglesia Gracía, Floreta Kurti, Dong Wu, Adriana Gherbon, Łukasz Nawacki, Alexandru Constantinescu, Natalia V. Shirinskaya, Alexander N. Zolotov, Sanjay Pandanaboyana, Tsukasa Ikeura, Tiago Cúrdia Gonçalves, Louise Rasmussen, Bodil Andersson, Ahmed Bouzid, Ahmed Saidani, Nándor Ács, Zoltán Sipos, Nelli Farkas, Balázs Tihanyi, Brigitta Teutsch, Johan Nilsson, Alexandra Mikó, Péter Hegyi |
| 264 | 1 | |c November 2025 | |
| 300 | |b Diagramme | ||
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Erstmals veröffentlicht: 4. Oktober 2025 | ||
| 500 | |a Gesehen am 27.11.2025 | ||
| 520 | |a Background Biliary acute pancreatitis (AP) during pregnancy is a challenging situation, and current guidelines for AP, pregnancy care, and surgery do not specifically address its management. This study investigated the safety and effectiveness of cholecystectomy and endoscopic retrograde cholangiopancreatography (ERCP) during pregnancy in AP. Methods This international retrospective multicenter cohort study encompassed questions related to demographic information, clinical presentation, management strategies, timing of cholecystectomy, approaches to the procedure, complications, and outcomes. Continuous variables were summarized as medians with interquartile ranges, and categorical variables as frequencies and percentages. Group comparisons used Welch's t-test, Pearson's chi-squared, or Fisher's exact tests. Results A total of 101 cases from 14 countries and 19 centers were enrolled. Cholecystectomy after mild AP during pregnancy had a lower rate of readmission due to recurrent AP or other gallstone-related complications compared with those who did not undergo surgery after a mild AP during pregnancy (0% vs. 24%; n = 0/17 vs. n = 12/49, p = 0.027). Cholecystectomy performed during pregnancy was associated with a low surgical complication rate, identical to that seen in postpartum procedures (12% vs. 10%; n = 2/17 vs. n = 3/30; p > 0.999). Preterm birth occurred in 7.1% (n = 1/14) of patients with cholecystectomy versus 11% (n = 5/45) without. Fetal loss after surgery occurred only in the first trimester (n = 3/17 vs. n = 1/49). No difference was seen in readmission (5%, n = 1/21 vs. 27%, n = 4/15; p = 0.138), fetal loss (5%, n = 1/21 vs. 27%, n = 4/15; p = 0.138) and preterm birth (6%, n = 1/17 vs. 8%, n = 1/12; p > 0.999) between the surgical and ERCP groups. The fetal loss (9.1%, n = 2/22 vs. 5.4%, n = 4/74; p = 0.618) and preterm birth rates (5.9%, n = 1/17 vs. 12%, n = 8/65; p = 0.677) did not significantly differ between patients with and without ERCP during pregnancy. Conclusion Cholecystectomy is effective and safe in pregnant patients during the second or third trimester in cases of mild biliary pancreatitis. ERCP is safe in any trimester. | ||
| 700 | 1 | |a Szalai, Eszter Ágnes |e VerfasserIn |4 aut | |
| 700 | 1 | |a Erőss, Bálint |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hegyi, Péter Jenő |e VerfasserIn |4 aut | |
| 700 | 1 | |a Drug, Vasile Liviu |e VerfasserIn |4 aut | |
| 700 | 1 | |a Chooklin, Serge |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hirth, Michael |d 1986- |e VerfasserIn |0 (DE-588)1051645808 |0 (DE-627)786507624 |0 (DE-576)406937281 |4 aut | |
| 700 | 1 | |a Sandblom, Gabriel |e VerfasserIn |4 aut | |
| 700 | 1 | |a Sandblom, Vanessa |e VerfasserIn |4 aut | |
| 700 | 1 | |a Edergren, Åsa |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tlili, Ahmed |e VerfasserIn |4 aut | |
| 700 | 1 | |a Fendri, Sami |e VerfasserIn |4 aut | |
| 700 | 1 | |a Sirtl, Simon |e VerfasserIn |4 aut | |
| 700 | 1 | |a de la Iglesia Gracía, Daniel |e VerfasserIn |4 aut | |
| 700 | 1 | |a Kurti, Floreta |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wu, Dong |e VerfasserIn |4 aut | |
| 700 | 1 | |a Gherbon, Adriana |e VerfasserIn |4 aut | |
| 700 | 1 | |a Nawacki, Łukasz |e VerfasserIn |4 aut | |
| 700 | 1 | |a Constantinescu, Alexandru |e VerfasserIn |4 aut | |
| 700 | 1 | |a Shirinskaya, Natalia V. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Zolotov, Alexander N. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Pandanaboyana, Sanjay |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ikeura, Tsukasa |e VerfasserIn |4 aut | |
| 700 | 1 | |a Cúrdia Gonçalves, Tiago |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rasmussen, Louise |e VerfasserIn |4 aut | |
| 700 | 1 | |a Andersson, Bodil |e VerfasserIn |4 aut | |
| 700 | 1 | |a Bouzid, Ahmed |e VerfasserIn |4 aut | |
| 700 | 1 | |a Saidani, Ahmed |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ács, Nándor |e VerfasserIn |4 aut | |
| 700 | 1 | |a Sipos, Zoltán |e VerfasserIn |4 aut | |
| 700 | 1 | |a Farkas, Nelli |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tihanyi, Balázs |e VerfasserIn |4 aut | |
| 700 | 1 | |a Teutsch, Brigitta |e VerfasserIn |4 aut | |
| 700 | 1 | |a Nilsson, Johan |e VerfasserIn |4 aut | |
| 700 | 1 | |a Mikó, Alexandra |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hegyi, Péter |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t United european gastroenterology journal |d Hoboken, NJ : Wiley, 2013 |g 13(2025), 9 vom: Nov., Seite 1803-1811 |h Online-Ressource |w (DE-627)757134165 |w (DE-600)2728585-6 |w (DE-576)392328348 |x 2050-6414 |7 nnas |a Safety and effectiveness of cholecystectomy and endoscopic retrograde cholangiopancreatography in biliary pancreatitis during pregnancy BORN study |
| 773 | 1 | 8 | |g volume:13 |g year:2025 |g number:9 |g month:11 |g pages:1803-1811 |g extent:9 |a Safety and effectiveness of cholecystectomy and endoscopic retrograde cholangiopancreatography in biliary pancreatitis during pregnancy BORN study |
| 787 | 0 | 8 | |i Ergänzung |a Verdonk, Robert C. |t Acute biliary pancreatitis during pregnancy: time to step up our efforts!, in: United European Gastroenterology Journal |d 2025 |g Vol. 13(9), 1674-1675 |o 10.1002/ueg2.70111 |
| 856 | 4 | 0 | |u https://doi.org/10.1002/ueg2.70121 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/abs/10.1002/ueg2.70121 |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20251127 | ||
| 993 | |a Article | ||
| 994 | |a 2025 | ||
| 998 | |g 1051645808 |a Hirth, Michael |m 1051645808:Hirth, Michael |d 60000 |d 61100 |e 60000PH1051645808 |e 61100PH1051645808 |k 0/60000/ |k 1/60000/61100/ |p 7 | ||
| 999 | |a KXP-PPN1942674198 |e 4814722389 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"name":{"displayForm":["Dorottya Tarján, Eszter Ágnes Szalai, Bálint Erőss, Péter Jenő Hegyi, Vasile Liviu Drug, Serge Chooklin, Michael Hirth, Gabriel Sandblom, Vanessa Sandblom, Åsa Edergren, Ahmed Tlili, Sami Fendri, Simon Sirtl, Daniel de la Iglesia Gracía, Floreta Kurti, Dong Wu, Adriana Gherbon, Łukasz Nawacki, Alexandru Constantinescu, Natalia V. Shirinskaya, Alexander N. Zolotov, Sanjay Pandanaboyana, Tsukasa Ikeura, Tiago Cúrdia Gonçalves, Louise Rasmussen, Bodil Andersson, Ahmed Bouzid, Ahmed Saidani, Nándor Ács, Zoltán Sipos, Nelli Farkas, Balázs Tihanyi, Brigitta Teutsch, Johan Nilsson, Alexandra Mikó, Péter Hegyi"]},"id":{"doi":["10.1002/ueg2.70121"],"eki":["1942674198"]},"origin":[{"dateIssuedDisp":"November 2025","dateIssuedKey":"2025"}],"relHost":[{"id":{"eki":["757134165"],"zdb":["2728585-6"],"issn":["2050-6414"]},"origin":[{"publisherPlace":"Hoboken, NJ ; London","publisher":"Wiley ; Sage Publishing","dateIssuedKey":"2013","dateIssuedDisp":"2013-"}],"physDesc":[{"extent":"Online-Ressource"}],"title":[{"subtitle":"ueg journal","title":"United european gastroenterology journal","title_sort":"United european gastroenterology journal"}],"language":["eng"],"corporate":[{"display":"United European Gastroenterology","roleDisplay":"Herausgebendes Organ","role":"isb"}],"recId":"757134165","type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Safety and effectiveness of cholecystectomy and endoscopic retrograde cholangiopancreatography in biliary pancreatitis during pregnancy BORN studyUnited european gastroenterology journal","note":["Gesehen am 10.02.2021"],"titleAlt":[{"title":"Ueg journal"}],"part":{"volume":"13","text":"13(2025), 9 vom: Nov., Seite 1803-1811","extent":"9","year":"2025","issue":"9","pages":"1803-1811"},"pubHistory":["1.2013 -"]}],"physDesc":[{"extent":"9 S.","noteIll":"Diagramme"}],"person":[{"family":"Tarján","given":"Dorottya","display":"Tarján, Dorottya","roleDisplay":"VerfasserIn","role":"aut"},{"roleDisplay":"VerfasserIn","display":"Szalai, Eszter Ágnes","role":"aut","family":"Szalai","given":"Eszter Ágnes"},{"family":"Erőss","given":"Bálint","display":"Erőss, Bálint","roleDisplay":"VerfasserIn","role":"aut"},{"given":"Péter Jenő","family":"Hegyi","role":"aut","display":"Hegyi, Péter Jenő","roleDisplay":"VerfasserIn"},{"display":"Drug, Vasile Liviu","roleDisplay":"VerfasserIn","role":"aut","family":"Drug","given":"Vasile Liviu"},{"roleDisplay":"VerfasserIn","display":"Chooklin, Serge","role":"aut","family":"Chooklin","given":"Serge"},{"given":"Michael","family":"Hirth","role":"aut","display":"Hirth, Michael","roleDisplay":"VerfasserIn"},{"family":"Sandblom","given":"Gabriel","roleDisplay":"VerfasserIn","display":"Sandblom, Gabriel","role":"aut"},{"role":"aut","display":"Sandblom, Vanessa","roleDisplay":"VerfasserIn","given":"Vanessa","family":"Sandblom"},{"family":"Edergren","given":"Åsa","display":"Edergren, Åsa","roleDisplay":"VerfasserIn","role":"aut"},{"role":"aut","display":"Tlili, Ahmed","roleDisplay":"VerfasserIn","given":"Ahmed","family":"Tlili"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Fendri, Sami","given":"Sami","family":"Fendri"},{"given":"Simon","family":"Sirtl","role":"aut","roleDisplay":"VerfasserIn","display":"Sirtl, Simon"},{"given":"Daniel","family":"de la Iglesia Gracía","role":"aut","display":"de la Iglesia Gracía, Daniel","roleDisplay":"VerfasserIn"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Kurti, Floreta","given":"Floreta","family":"Kurti"},{"family":"Wu","given":"Dong","display":"Wu, Dong","roleDisplay":"VerfasserIn","role":"aut"},{"given":"Adriana","family":"Gherbon","role":"aut","display":"Gherbon, Adriana","roleDisplay":"VerfasserIn"},{"family":"Nawacki","given":"Łukasz","display":"Nawacki, Łukasz","roleDisplay":"VerfasserIn","role":"aut"},{"display":"Constantinescu, Alexandru","roleDisplay":"VerfasserIn","role":"aut","family":"Constantinescu","given":"Alexandru"},{"display":"Shirinskaya, Natalia V.","roleDisplay":"VerfasserIn","role":"aut","family":"Shirinskaya","given":"Natalia V."},{"family":"Zolotov","given":"Alexander N.","roleDisplay":"VerfasserIn","display":"Zolotov, Alexander N.","role":"aut"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Pandanaboyana, Sanjay","given":"Sanjay","family":"Pandanaboyana"},{"given":"Tsukasa","family":"Ikeura","role":"aut","display":"Ikeura, Tsukasa","roleDisplay":"VerfasserIn"},{"family":"Cúrdia Gonçalves","given":"Tiago","roleDisplay":"VerfasserIn","display":"Cúrdia Gonçalves, Tiago","role":"aut"},{"family":"Rasmussen","given":"Louise","display":"Rasmussen, Louise","roleDisplay":"VerfasserIn","role":"aut"},{"family":"Andersson","given":"Bodil","roleDisplay":"VerfasserIn","display":"Andersson, Bodil","role":"aut"},{"family":"Bouzid","given":"Ahmed","display":"Bouzid, Ahmed","roleDisplay":"VerfasserIn","role":"aut"},{"role":"aut","display":"Saidani, Ahmed","roleDisplay":"VerfasserIn","given":"Ahmed","family":"Saidani"},{"given":"Nándor","family":"Ács","role":"aut","display":"Ács, Nándor","roleDisplay":"VerfasserIn"},{"family":"Sipos","given":"Zoltán","roleDisplay":"VerfasserIn","display":"Sipos, Zoltán","role":"aut"},{"family":"Farkas","given":"Nelli","display":"Farkas, Nelli","roleDisplay":"VerfasserIn","role":"aut"},{"roleDisplay":"VerfasserIn","display":"Tihanyi, Balázs","role":"aut","family":"Tihanyi","given":"Balázs"},{"display":"Teutsch, Brigitta","roleDisplay":"VerfasserIn","role":"aut","family":"Teutsch","given":"Brigitta"},{"family":"Nilsson","given":"Johan","roleDisplay":"VerfasserIn","display":"Nilsson, Johan","role":"aut"},{"given":"Alexandra","family":"Mikó","role":"aut","display":"Mikó, Alexandra","roleDisplay":"VerfasserIn"},{"family":"Hegyi","given":"Péter","display":"Hegyi, Péter","roleDisplay":"VerfasserIn","role":"aut"}],"title":[{"title_sort":"Safety and effectiveness of cholecystectomy and endoscopic retrograde cholangiopancreatography in biliary pancreatitis during pregnancy","subtitle":"BORN study","title":"Safety and effectiveness of cholecystectomy and endoscopic retrograde cholangiopancreatography in biliary pancreatitis during pregnancy"}],"language":["eng"],"recId":"1942674198","note":["Erstmals veröffentlicht: 4. Oktober 2025","Gesehen am 27.11.2025"],"type":{"bibl":"article-journal","media":"Online-Ressource"}} | ||
| SRT | |a TARJANDOROSAFETYANDE2025 | ||