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Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions

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Glioblastoma is the most common type of malignant primary brain tumor and a major cause of morbidity and mortality. In 2021, the World Health Organization updated the classification of Central Nervous System (CNS) tumors to restrict glioblastomas to isocitrate dehydrogenase-wildtype (IDHwt) tumors,...

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Main Authors: Wen, Patrick Y. (Author) , Weller, Michael (Author) , Lee, Eudocia Quant (Author) , Touat, Mehdi (Author) , Khasraw, Mustafa (Author) , Rahman, Rifaquat (Author) , Platten, Michael (Author) , Lim, Michael (Author) , Winkler, Frank (Author) , Horbinski, Craig (Author) , Verhaak, Roel G W (Author) , Huang, Raymond Y (Author) , Ahluwalia, Manmeet S (Author) , Albert, Nathalie L (Author) , Tonn, Joerg-Christian (Author) , Schiff, David (Author) , Barnholtz-Sloan, Jill S (Author) , Ostrom, Quinn (Author) , Aldape, Kenneth D (Author) , Batchelor, Tracy T. (Author) , Bindra, Ranjit S (Author) , Chiocca, E Antonio (Author) , Cloughesy, Timothy (Author) , DeGroot, John F (Author) , French, Pim (Author) , Galanis, Evanthia (Author) , Galldiks, Norbert (Author) , Gilbert, Mark R. (Author) , Hegi, Monika E. (Author) , Lassman, Andrew B (Author) , Le Rhun, Emilie (Author) , Mehta, Minesh P. (Author) , Mellinghoff, Ingo K (Author) , Minniti, Giuseppe (Author) , Roth, Patrick (Author) , Sanson, Marc (Author) , Taphoorn, Andreas, Martin J B (Author) , Weiss, von Deimling, Tobias (Author) , Wick, Wolfgang (Author) , Zadeh, Gelareh (Author) , Reardon, David A. (Author) , Chang, Susan M (Author) , Short, Susan C (Author) , Van den Bent, Martin J. (Author) , Preusser, Matthias (Author)
Format: Article (Journal)
Language:English
Published: 13 August 2025
In: Neuro-Oncology
Year: 2025, Pages: 1-38
ISSN:1523-5866
DOI:10.1093/neuonc/noaf177
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1093/neuonc/noaf177
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Author Notes:Patrick Y. Wen, Michael Weller, Eudocia Q. Lee, Mehdi Touat, Mustafa Khasraw, Rifaquat Rahman, Michael Platten, Michael Lim, Frank Winkler, Craig Horbinski, Roel G.W. Verhaak, Raymond Y. Huang, Manmeet S. Ahluwalia, Nathalie L. Albert, Joerg-Christian Tonn, David Schiff, Jill S. Barnholtz-Sloan, Quinn Ostrom, Kenneth D. Aldape, Tracy T. Batchelor, Ranjit S. Bindra, E. Antonio Chiocca, Timothy F. Cloughesy, John F. DeGroot, Pim French, Evanthia Galanis, Norbert Galldiks, Mark R. Gilbert, Monika E. Hegi, Andrew B. Lassman, Emilie Le Rhun, Minesh P. Mehta, Ingo K. Mellinghoff, Giuseppe Minniti, Patrick Roth, Marc Sanson, Andreas, Martin J.B. Taphoorn, von Deimling, Tobias Weiss, Wolfgang Wick, Gelareh Zadeh, David A. Reardon, Susan M. Chang, Susan C. Short, Martin J. van den Bent, Matthias Preusser
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Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions by Wen, Patrick Y. (Author) , Weller, Michael (Author) , Lee, Eudocia Quant (Author) , Alexander, Brian M. (Author) , Barnholtz-Sloan, Jill S. (Author) , Barthel, Floris P. (Author) , Batchelor, Tracy T. (Author) , Bindra, Ranjit S. (Author) , Chang, Susan M. (Author) , Chiocca, E. Antonio (Author) , Cloughesy, Timothy (Author) , DeGroot, John F. (Author) , Galanis, Evanthia (Author) , Gilbert, Mark R. (Author) , Hegi, Monika E. (Author) , Horbinski, Craig (Author) , Huang, Raymond Y. (Author) , Lassman, Andrew B. (Author) , Le Rhun, Emilie (Author) , Lim, Michael J. (Author) , Mehta, Minesh P. (Author) , Mellinghoff, Ingo K. (Author) , Minniti, Giuseppe (Author) , Nathanson, David (Author) , Platten, Michael (Author) , Preusser, Matthias (Author) , Roth, Patrick (Author) , Sanson, Marc (Author) , Schiff, David (Author) , Short, Susan C. (Author) , Taphoorn, Martin J. B. (Author) , Tonn, Joerg-Christian (Author) , Tsang, Jonathan (Author) , Verhaak, Roel G. W. (Author) , Deimling, Andreas von (Author) , Wick, Wolfgang (Author) , Zadeh, Gelareh (Author) , Reardon, David A. (Author) , Aldape, Kenneth D. (Author) , Van den Bent, Martin J. (Author) ,


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