Effects of generative artificial intelligence on cognitive effort and task performance: study protocol for a randomized controlled experiment among college students

BackgroundThe advancement of generative artificial intelligence (AI) has shown great potential to enhance productivity in many cognitive tasks. However, concerns are raised that the use of generative AI may erode human cognition due to over-reliance. Conversely, others argue that generative AI holds...

Full description

Saved in:
Bibliographic Details
Main Authors: Chen, Youjie (Author) , Wang, Yingying (Author) , Wüstenberg, Torsten (Author) , Kizilcec, Rene F. (Author) , Fan, Yiwen (Author) , Li, Yanfei (Author) , Lu, Bin (Author) , Yuan, Meng (Author) , Zhang, Junlai (Author) , Zhang, Ziyue (Author) , Geldsetzer, Pascal (Author) , Chen, Simiao (Author) , Bärnighausen, Till (Author)
Format: Article (Journal)
Language:English
Published: 11 July 2025
In: Trials
Year: 2025, Volume: 26, Pages: 1-15
ISSN:1468-6694
DOI:10.1186/s13063-025-08950-3
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13063-025-08950-3
Get full text
Author Notes:Youjie Chen, Yingying Wang, Torsten Wuestenberg, Rene F. Kizilcec, Yiwen Fan, Yanfei Li, Bin Lu, Meng Yuan, Junlai Zhang, Ziyue Zhang, Pascal Geldsetzer, Simiao Chen and Till Baernighausen

MARC

LEADER 00000caa a2200000 c 4500
001 1942944608
003 DE-627
005 20260113110400.0
007 cr uuu---uuuuu
008 251201s2025 xx |||||o 00| ||eng c
024 7 |a 10.1186/s13063-025-08950-3  |2 doi 
035 |a (DE-627)1942944608 
035 |a (DE-599)KXP1942944608 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Chen, Youjie  |e VerfasserIn  |0 (DE-588)1383107432  |0 (DE-627)1942945523  |4 aut 
245 1 0 |a Effects of generative artificial intelligence on cognitive effort and task performance  |b study protocol for a randomized controlled experiment among college students  |c Youjie Chen, Yingying Wang, Torsten Wuestenberg, Rene F. Kizilcec, Yiwen Fan, Yanfei Li, Bin Lu, Meng Yuan, Junlai Zhang, Ziyue Zhang, Pascal Geldsetzer, Simiao Chen and Till Baernighausen 
264 1 |c 11 July 2025 
300 |b Illustrationen 
300 |a 15 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 01.12.2025 
520 |a BackgroundThe advancement of generative artificial intelligence (AI) has shown great potential to enhance productivity in many cognitive tasks. However, concerns are raised that the use of generative AI may erode human cognition due to over-reliance. Conversely, others argue that generative AI holds the promise to augment human cognition by automating menial tasks and offering insights that extend one's cognitive abilities. To better understand the role of generative AI in human cognition, we study how college students use a generative AI tool to support their analytical writing in an educational context. We will examine the effect of using generative AI on cognitive effort, a major aspect of human cognition that reflects the extent of mental resources an individual allocates during the cognitive process. We will also examine the effect on writing performance achieved through the human-generative AI collaboration.MethodsThis study is a randomized controlled lab experiment that compares the effects of using generative AI (intervention group) versus not using it (control group) on cognitive effort and writing performance in an analytical writing task designed as a hypothetical writing class assignment for college students. During the experiment, eye-tracking technology will monitor eye movements and pupil dilation. Functional near-infrared spectroscopy (fNIRS) will collect brain hemodynamic responses. A survey will measure individuals' perceptions of the writing task and their attitudes on generative AI. We will recruit 160 participants (aged 18-35 years) from a German university where the research will be conducted.DiscussionThis trial aims to establish the causal effects of generative AI on cognitive effort and task performance through a randomized controlled experiment. The findings aim to offer insights for policymakers in regulating generative AI and inform the responsible design and use of generative AI tools.Trial registration.ClinicalTrials.gov NCT06511102. Registered on July 15, 2024. https://clinicaltrials.gov/study/NCT06511102DiscussionThis trial aims to establish the causal effects of generative AI on cognitive effort and task performance through a randomized controlled experiment. The findings aim to offer insights for policymakers in regulating generative AI and inform the responsible design and use of generative AI tools.Trial registration.ClinicalTrials.gov NCT06511102. Registered on July 15, 2024. https://clinicaltrials.gov/study/NCT06511102DiscussionThis trial aims to establish the causal effects of generative AI on cognitive effort and task performance through a randomized controlled experiment. The findings aim to offer insights for policymakers in regulating generative AI and inform the responsible design and use of generative AI tools.Trial registration.ClinicalTrials.gov NCT06511102. Registered on July 15, 2024. https://clinicaltrials.gov/study/NCT06511102 
650 4 |a Analytical writing 
650 4 |a Cognitive effort 
650 4 |a Critical thinking 
650 4 |a CRITICAL THINKING 
650 4 |a Eye-tracking 
650 4 |a Functional near-infrared spectroscopy 
650 4 |a Generative artificial intelligence 
650 4 |a Human cognition 
650 4 |a MEMORY 
650 4 |a Randomized controlled trial 
700 1 |a Wang, Yingying  |e VerfasserIn  |4 aut 
700 1 |a Wüstenberg, Torsten  |e VerfasserIn  |0 (DE-588)122858933X  |0 (DE-627)1750440091  |4 aut 
700 1 |a Kizilcec, Rene F.  |e VerfasserIn  |4 aut 
700 1 |a Fan, Yiwen  |e VerfasserIn  |4 aut 
700 1 |a Li, Yanfei  |e VerfasserIn  |0 (DE-588)1363917021  |0 (DE-627)1923593315  |4 aut 
700 1 |a Lu, Bin  |e VerfasserIn  |4 aut 
700 1 |a Yuan, Meng  |e VerfasserIn  |4 aut 
700 1 |a Zhang, Junlai  |e VerfasserIn  |4 aut 
700 1 |a Zhang, Ziyue  |e VerfasserIn  |4 aut 
700 1 |a Geldsetzer, Pascal  |e VerfasserIn  |0 (DE-588)1073833623  |0 (DE-627)829590501  |0 (DE-576)435307592  |4 aut 
700 1 |a Chen, Simiao  |e VerfasserIn  |0 (DE-588)1138719242  |0 (DE-627)896263061  |0 (DE-576)492659265  |4 aut 
700 1 |a Bärnighausen, Till  |d 1969-  |e VerfasserIn  |0 (DE-588)120262029  |0 (DE-627)080560512  |0 (DE-576)178470848  |4 aut 
773 0 8 |i Enthalten in  |t Trials  |d London : BioMed Central, 2000  |g 26(2025), Artikel-ID 244, Seite 1-15  |h Online-Ressource  |w (DE-627)326173552  |w (DE-600)2040523-6  |w (DE-576)107014556  |x 1468-6694  |7 nnas  |a Effects of generative artificial intelligence on cognitive effort and task performance study protocol for a randomized controlled experiment among college students 
773 1 8 |g volume:26  |g year:2025  |g elocationid:244  |g pages:1-15  |g extent:15  |a Effects of generative artificial intelligence on cognitive effort and task performance study protocol for a randomized controlled experiment among college students 
856 4 0 |u https://doi.org/10.1186/s13063-025-08950-3  |x Verlag  |x Resolving-System  |z kostenfrei  |3 Volltext  |7 0 
951 |a AR 
992 |a 20251201 
993 |a Article 
994 |a 2025 
998 |g 120262029  |a Bärnighausen, Till  |m 120262029:Bärnighausen, Till  |d 910000  |d 912800  |e 910000PB120262029  |e 912800PB120262029  |k 0/910000/  |k 1/910000/912800/  |p 13  |y j 
998 |g 1138719242  |a Chen, Simiao  |m 1138719242:Chen, Simiao  |d 910000  |d 912800  |d 50000  |e 910000PC1138719242  |e 912800PC1138719242  |e 50000PC1138719242  |k 0/910000/  |k 1/910000/912800/  |k 0/50000/  |p 12 
998 |g 1363917021  |a Li, Yanfei  |m 1363917021:Li, Yanfei  |d 50000  |e 50000PL1363917021  |k 0/50000/  |p 6 
998 |g 122858933X  |a Wüstenberg, Torsten  |m 122858933X:Wüstenberg, Torsten  |d 620000  |d 621000  |e 620000PW122858933X  |e 621000PW122858933X  |k 0/620000/  |k 1/620000/621000/  |p 3 
999 |a KXP-PPN1942944608  |e 4818028983 
BIB |a Y 
SER |a journal 
JSO |a {"type":{"media":"Online-Ressource","bibl":"article-journal"},"origin":[{"dateIssuedKey":"2025","dateIssuedDisp":"11 July 2025"}],"recId":"1942944608","note":["Gesehen am 01.12.2025"],"relHost":[{"title":[{"title":"Trials","title_sort":"Trials"}],"part":{"year":"2025","text":"26(2025), Artikel-ID 244, Seite 1-15","volume":"26","extent":"15","pages":"1-15"},"language":["eng"],"pubHistory":["1.2000 -"],"titleAlt":[{"title":"Current controlled trials in cardiovascular medicine"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"origin":[{"publisher":"BioMed Central","dateIssuedDisp":"2000-","dateIssuedKey":"2000","publisherPlace":"London"}],"recId":"326173552","disp":"Effects of generative artificial intelligence on cognitive effort and task performance study protocol for a randomized controlled experiment among college studentsTrials","physDesc":[{"extent":"Online-Ressource"}],"id":{"eki":["326173552"],"issn":["1468-6694","1745-6215"],"zdb":["2040523-6"]},"note":["Gesehen am 26.09.22"]}],"id":{"eki":["1942944608"],"doi":["10.1186/s13063-025-08950-3"]},"physDesc":[{"noteIll":"Illustrationen","extent":"15 S."}],"name":{"displayForm":["Youjie Chen, Yingying Wang, Torsten Wuestenberg, Rene F. Kizilcec, Yiwen Fan, Yanfei Li, Bin Lu, Meng Yuan, Junlai Zhang, Ziyue Zhang, Pascal Geldsetzer, Simiao Chen and Till Baernighausen"]},"person":[{"family":"Chen","display":"Chen, Youjie","role":"aut","given":"Youjie"},{"family":"Wang","display":"Wang, Yingying","given":"Yingying","role":"aut"},{"role":"aut","given":"Torsten","display":"Wüstenberg, Torsten","family":"Wüstenberg"},{"role":"aut","given":"Rene F.","display":"Kizilcec, Rene F.","family":"Kizilcec"},{"family":"Fan","display":"Fan, Yiwen","role":"aut","given":"Yiwen"},{"family":"Li","display":"Li, Yanfei","given":"Yanfei","role":"aut"},{"display":"Lu, Bin","given":"Bin","role":"aut","family":"Lu"},{"role":"aut","given":"Meng","display":"Yuan, Meng","family":"Yuan"},{"family":"Zhang","display":"Zhang, Junlai","given":"Junlai","role":"aut"},{"family":"Zhang","display":"Zhang, Ziyue","given":"Ziyue","role":"aut"},{"family":"Geldsetzer","display":"Geldsetzer, Pascal","given":"Pascal","role":"aut"},{"display":"Chen, Simiao","given":"Simiao","role":"aut","family":"Chen"},{"display":"Bärnighausen, Till","given":"Till","role":"aut","family":"Bärnighausen"}],"language":["eng"],"title":[{"title":"Effects of generative artificial intelligence on cognitive effort and task performance","subtitle":"study protocol for a randomized controlled experiment among college students","title_sort":"Effects of generative artificial intelligence on cognitive effort and task performance"}]} 
SRT |a CHENYOUJIEEFFECTSOFG1120