A novel complex of nucleoporins, which Includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores
In a genetic screen for nucleoporin-interacting components, a novel nuclear pore protein Nup84p, which exhibits homology to mammalian Nup107p, was isolated. Nup84p forms a complex with five proteins, of which Nup120p, Nup85p, Sec13p, and a Sec13p homolog were identified. Upon isolation of Sec13p-Pro...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
26 January 1996
|
| In: |
Cell
Year: 1996, Jahrgang: 84, Heft: 2, Pages: 265-275 |
| ISSN: | 1097-4172 |
| DOI: | 10.1016/S0092-8674(00)80981-2 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/S0092-8674(00)80981-2 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0092867400809812 
|
| Verfasserangaben: | Symeon Siniossoglou, Christian Wimmer, Michael Rieger, Valerie Doye, Hildegard Tekotte, Chris Weise, Sonja Emig, Alexandra Segref, and Edward C. Hurt |
MARC
| LEADER | 00000naa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1943106835 | ||
| 003 | DE-627 | ||
| 005 | 20251202135615.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 251202s1996 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/S0092-8674(00)80981-2 |2 doi | |
| 035 | |a (DE-627)1943106835 | ||
| 035 | |a (DE-599)KXP1943106835 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Siniossoglou, Symeon |e VerfasserIn |0 (DE-588)1382410964 |0 (DE-627)1942077750 |4 aut | |
| 245 | 1 | 2 | |a A novel complex of nucleoporins, which Includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores |c Symeon Siniossoglou, Christian Wimmer, Michael Rieger, Valerie Doye, Hildegard Tekotte, Chris Weise, Sonja Emig, Alexandra Segref, and Edward C. Hurt |
| 264 | 1 | |c 26 January 1996 | |
| 300 | |a 11 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Elektronische Reproduktion der Druck-Ausgabe 27. Juli 2004 | ||
| 500 | |a Gesehen am 02.12.2025 | ||
| 520 | |a In a genetic screen for nucleoporin-interacting components, a novel nuclear pore protein Nup84p, which exhibits homology to mammalian Nup107p, was isolated. Nup84p forms a complex with five proteins, of which Nup120p, Nup85p, Sec13p, and a Sec13p homolog were identified. Upon isolation of Sec13p-ProtA, nucleoporins were still associated, but the major copurifying band was a 150 kDa protein, showing that Sec13p occurs in two complexes. Disruption of any of the genes encoding Nup84p, Nup85p, or Nup120p caused defects in nuclear membrane and nuclear pore complex organization, as well as in poly(A)+ RNA transport. Thus, the Nup84p complex in conjunction with Sec13-type proteins is required for correct nuclear pore biogenesis. | ||
| 700 | 1 | |a Wimmer, Christian |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rieger, Michael |e VerfasserIn |4 aut | |
| 700 | 1 | |a Doye, Valerie |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tekotte, Hildegard |e VerfasserIn |4 aut | |
| 700 | 1 | |a Weise, Chris |e VerfasserIn |4 aut | |
| 700 | 1 | |a Emig, Sonja |e VerfasserIn |4 aut | |
| 700 | 1 | |a Segref, Alexandra |e VerfasserIn |0 (DE-588)1383113955 |0 (DE-627)1942959729 |4 aut | |
| 700 | 1 | |a Hurt, Ed |d 1955- |e VerfasserIn |0 (DE-588)11021952X |0 (DE-627)729291863 |0 (DE-576)373308574 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Cell |d [Cambridge, Mass.] : Cell Press, 1974 |g 84(1996), 2, Seite 265-275 |h Online-Ressource |w (DE-627)320416127 |w (DE-600)2001951-8 |w (DE-576)090881370 |x 1097-4172 |7 nnas |a A novel complex of nucleoporins, which Includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores |
| 773 | 1 | 8 | |g volume:84 |g year:1996 |g number:2 |g pages:265-275 |g extent:11 |a A novel complex of nucleoporins, which Includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores |
| 856 | 4 | 0 | |u https://doi.org/10.1016/S0092-8674(00)80981-2 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.sciencedirect.com/science/article/pii/S0092867400809812 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20251202 | ||
| 993 | |a Article | ||
| 994 | |a 1996 | ||
| 998 | |g 11021952X |a Hurt, Ed |m 11021952X:Hurt, Ed |d 700000 |d 711000 |e 700000PH11021952X |e 711000PH11021952X |k 0/700000/ |k 1/700000/711000/ |p 9 |y j | ||
| 999 | |a KXP-PPN1943106835 |e 4818536237 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"language":["eng"],"title":[{"title":"A novel complex of nucleoporins, which Includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores","title_sort":"novel complex of nucleoporins, which Includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores"}],"person":[{"given":"Symeon","role":"aut","display":"Siniossoglou, Symeon","family":"Siniossoglou"},{"role":"aut","given":"Christian","display":"Wimmer, Christian","family":"Wimmer"},{"family":"Rieger","display":"Rieger, Michael","role":"aut","given":"Michael"},{"family":"Doye","display":"Doye, Valerie","role":"aut","given":"Valerie"},{"family":"Tekotte","display":"Tekotte, Hildegard","role":"aut","given":"Hildegard"},{"family":"Weise","display":"Weise, Chris","role":"aut","given":"Chris"},{"family":"Emig","display":"Emig, Sonja","role":"aut","given":"Sonja"},{"display":"Segref, Alexandra","role":"aut","given":"Alexandra","family":"Segref"},{"given":"Ed","role":"aut","display":"Hurt, Ed","family":"Hurt"}],"name":{"displayForm":["Symeon Siniossoglou, Christian Wimmer, Michael Rieger, Valerie Doye, Hildegard Tekotte, Chris Weise, Sonja Emig, Alexandra Segref, and Edward C. Hurt"]},"relHost":[{"disp":"A novel complex of nucleoporins, which Includes Sec13p and a Sec13p homolog, is essential for normal nuclear poresCell","physDesc":[{"extent":"Online-Ressource"}],"id":{"zdb":["2001951-8"],"issn":["1097-4172"],"eki":["320416127"]},"note":["Gesehen am 11.03.24"],"origin":[{"dateIssuedKey":"1974","dateIssuedDisp":"1974-","publisher":"Cell Press ; Elsevier","publisherPlace":"[Cambridge, Mass.] ; New York, NY"}],"recId":"320416127","type":{"media":"Online-Ressource","bibl":"periodical"},"pubHistory":["1.1974 -"],"title":[{"title":"Cell","title_sort":"Cell"}],"part":{"text":"84(1996), 2, Seite 265-275","year":"1996","volume":"84","pages":"265-275","extent":"11","issue":"2"},"language":["eng"]}],"note":["Elektronische Reproduktion der Druck-Ausgabe 27. Juli 2004","Gesehen am 02.12.2025"],"id":{"eki":["1943106835"],"doi":["10.1016/S0092-8674(00)80981-2"]},"physDesc":[{"extent":"11 S."}],"origin":[{"dateIssuedDisp":"26 January 1996","dateIssuedKey":"1996"}],"recId":"1943106835","type":{"media":"Online-Ressource","bibl":"article-journal"}} | ||
| SRT | |a SINIOSSOGLNOVELCOMPL2619 | ||