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Impact of adjuvant endocrine therapy utilization in male patients with early breast cancer: results from a large German real-world claims data analysis

Male breast cancer (BC) is a rare entity and represents a significant clinical challenge due to its late diagnosis and resulting poorer prognosis compared to female BC. As shown by prior studies, approximately 99% of male BC patients are hormone receptor-positive (HR +). This study aimed to evaluate...

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Main Authors: Dannehl, Dominik (Author) , Dijkstra, Tjeerd Maarten Hein (Author) , Au, Alexandra von (Author) , Scholz, Anna (Author) , Volmer, Léa (Author) , Hahn, Markus (Author) , Hawighorst, Sabine (Author) , Chaudhuri, Ariane (Author) , Ţăran, Florin-Andrei (Author) , Wallwiener, Markus (Author) , Bauer, Armin (Author) , Wallwiener, Diethelm (Author) , Brucker, Sara (Author) , Wallwiener, Stephanie (Author) , Hartkopf, Andreas (Author) , Engler, Tobias (Author)
Format: Article (Journal)
Language:English
Published: 17 October 2025
In: Archives of gynecology and obstetrics
Year: 2025, Volume: 312, Issue: 6, Pages: 2123-2129
ISSN:1432-0711
DOI:10.1007/s00404-025-08198-x
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00404-025-08198-x
Resolving-System, kostenfrei: https://doi.org/10.1007/s00404-025-08198-x
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00404-025-08198-x
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Author Notes:Dominik Dannehl, Tjeerd Maarten Hein Dijkstra, Alexandra von Au, Anna Sophie Scholz, Léa Louise Volmer, Markus Hahn, Sabine Hawighorst-Knapstein, Ariane Chaudhuri, Florin-Andrei Taran, Markus Wallwiener, Armin Bauer, Diethelm Wallwiener, Sara Yvonne Brucker, Stephanie Wallwiener, Andreas Hartkopf, Tobias Engler
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Summary:Male breast cancer (BC) is a rare entity and represents a significant clinical challenge due to its late diagnosis and resulting poorer prognosis compared to female BC. As shown by prior studies, approximately 99% of male BC patients are hormone receptor-positive (HR +). This study aimed to evaluate the utilization and impact of adjuvant endocrine therapy (ET) in male early BC patients using a large German real-world claims dataset.
Physical Description:Online Resource
ISSN:1432-0711
DOI:10.1007/s00404-025-08198-x

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