Accelerated vs. conventionally fractionated postoperative radiotherapy of non-small cell lung cancer: final results of the prematurely terminated PORTAF trial
A prolonged overall treatment time (OTT) has been demonstrated to adversely affect the primary radiation therapy (RT) outcome in various solid tumors, including non-small cell lung cancer (NSCLC). Retrospective data from our group suggested an advantage of shorter OTT also for postoperative RT (PORT...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
15 July 2025
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| In: |
Strahlentherapie und Onkologie
Year: 2025, Pages: ? |
| ISSN: | 1439-099X |
| DOI: | 10.1007/s00066-025-02422-y |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00066-025-02422-y
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| Verfasserangaben: | Rebecca Bütof, Lydia Koi, Steffen Löck, Steffen Appold, Steffen Drewes, Dirk Koschel, Jörg Kotzerke, Ursula Nestle, Sonja Adebahr, Daniel Zips, Frank Heinzelmann, Thomas Hehr, Dagmar Bucher, Jürgen Heide, Claus Belka, Farkhad Manapov, Ewa Wasilewska-Tesluk, Jochen Fleckenstein, Mechthild Krause, Esther G.C. Troost, Michael Baumann |
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| 520 | |a A prolonged overall treatment time (OTT) has been demonstrated to adversely affect the primary radiation therapy (RT) outcome in various solid tumors, including non-small cell lung cancer (NSCLC). Retrospective data from our group suggested an advantage of shorter OTT also for postoperative RT (PORT) in patients with NSCLC. The PORTAF trial (ClinicalTrials.gov: NCT02189967) was initiated to prospectively test this hypothesis. | ||
| 650 | 4 | |a Fractionation | |
| 650 | 4 | |a Non-small-cell lung cancer | |
| 650 | 4 | |a Overall treatment time | |
| 650 | 4 | |a Positron-emission tomography | |
| 650 | 4 | |a Postoperative radiotherapy | |
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