CisBP-RNA: a web resource for eukaryotic RNA-binding proteins and their motifs
RNA-binding proteins (RBPs) are key mediators of post-transcriptional gene regulation, including splicing, transport, stability, and other facets of RNA metabolism. Many RBPs exert their function through sequence-specific protein-RNA interactions. RBP RNA-binding specificity models, or motifs, are t...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
29 October 2025
|
| In: |
Nucleic acids research
Year: 2025, Pages: 1-8 |
| ISSN: | 1362-4962 |
| DOI: | 10.1093/nar/gkaf1081 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1093/nar/gkaf1081
|
| Author Notes: | Diego A. Rosado-Tristani, Mihai Albu, Xiaoting Chen, Alexander Sasse, Kaitlin U. Laverty, Debashish Ray, Cyrus L. Tam, Kevin Ernst, Lucinda P. Lawson, Quaid D. Morris, Timothy R. Hughes, Matthew T. Weirauch |
MARC
| LEADER | 00000naa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1945019271 | ||
| 003 | DE-627 | ||
| 005 | 20251208114637.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 251208s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1093/nar/gkaf1081 |2 doi | |
| 035 | |a (DE-627)1945019271 | ||
| 035 | |a (DE-599)KXP1945019271 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Rosado-Tristani, Diego |e VerfasserIn |0 (DE-588)1383729247 |0 (DE-627)1945020970 |4 aut | |
| 245 | 1 | 0 | |a CisBP-RNA |b a web resource for eukaryotic RNA-binding proteins and their motifs |c Diego A. Rosado-Tristani, Mihai Albu, Xiaoting Chen, Alexander Sasse, Kaitlin U. Laverty, Debashish Ray, Cyrus L. Tam, Kevin Ernst, Lucinda P. Lawson, Quaid D. Morris, Timothy R. Hughes, Matthew T. Weirauch |
| 264 | 1 | |c 29 October 2025 | |
| 300 | |b Illustrationen | ||
| 300 | |a 8 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Veröffentlicht: 29. Oktober 2025 | ||
| 500 | |a Gesehen am 08.12.2025 | ||
| 520 | |a RNA-binding proteins (RBPs) are key mediators of post-transcriptional gene regulation, including splicing, transport, stability, and other facets of RNA metabolism. Many RBPs exert their function through sequence-specific protein-RNA interactions. RBP RNA-binding specificity models, or motifs, are thus essential for understanding post-transcriptional gene regulatory mechanisms. Here, we present CisBP-RNA (Catalog of inferred sequence Binding Preferences of RNA-binding proteins), a freely available web-based database that provides centralized access to eukaryotic RBP motif data. A key feature of CisBP-RNA is the availability of both experimentally determined motifs and motifs that are computationally predicted via our homology-based approaches. The current version of CisBP-RNA catalogs >148 000 sequence-specific RBPs across 690 eukaryotic species. Motifs are currently available for >34 000 of these RBPs. Motif data are available for download in a variety of formats for downstream computational analyses. In addition, CisBP-RNA provides user-friendly web-hosted tools to scan for predicted RBP binding sites, predicts motifs for a protein of interest, and compares a motif to motifs contained in the database. The CisBP-RNA database can be accessed through www.cisbp.org/rna/. | ||
| 700 | 1 | |a Albu, Mihai |e VerfasserIn |4 aut | |
| 700 | 1 | |a Chen, Xiaoting |e VerfasserIn |4 aut | |
| 700 | 1 | |a Sasse, Alexander |e VerfasserIn |0 (DE-588)1383728798 |0 (DE-627)1945020016 |4 aut | |
| 700 | 1 | |a Laverty, Kaitlin U |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ray, Debashish |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tam, Cyrus L |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ernst, Kevin |e VerfasserIn |4 aut | |
| 700 | 1 | |a Lawson, Lucinda P |e VerfasserIn |4 aut | |
| 700 | 1 | |a Morris, Quaid D |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hughes, Timothy R |e VerfasserIn |4 aut | |
| 700 | 1 | |a Weirauch, Matthew T |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Nucleic acids research |d Oxford : Oxford Univ. Press, 1974 |g (2025), Artikel-ID gkaf1081, Seite 1-8 |h Online-Ressource |w (DE-627)26813250X |w (DE-600)1472175-2 |w (DE-576)07760878X |x 1362-4962 |7 nnas |a CisBP-RNA a web resource for eukaryotic RNA-binding proteins and their motifs |
| 773 | 1 | 8 | |g year:2025 |g elocationid:gkaf1081 |g pages:1-8 |g extent:8 |a CisBP-RNA a web resource for eukaryotic RNA-binding proteins and their motifs |
| 856 | 4 | 0 | |u https://doi.org/10.1093/nar/gkaf1081 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |7 0 |
| 951 | |a AR | ||
| 992 | |a 20251208 | ||
| 993 | |a Article | ||
| 994 | |a 2025 | ||
| 998 | |g 1383728798 |a Sasse, Alexander |m 1383728798:Sasse, Alexander |d 500000 |d 590010 |e 500000PS1383728798 |e 590010PS1383728798 |k 0/500000/ |k 1/500000/590010/ |p 4 | ||
| 999 | |a KXP-PPN1945019271 |e 4824334705 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"disp":"CisBP-RNA a web resource for eukaryotic RNA-binding proteins and their motifsNucleic acids research","type":{"bibl":"periodical","media":"Online-Ressource"},"language":["eng"],"recId":"26813250X","physDesc":[{"extent":"Online-Ressource"}],"note":["Gesehen am 15.09.2025","Ungezählte Beil.: Database issue; Web server issue"],"title":[{"title":"Nucleic acids research","title_sort":"Nucleic acids research"}],"titleAlt":[{"title":"NAR online"},{"title":"NAR"},{"title":"Database issue"},{"title":"Web server issue"}],"pubHistory":["1.1974 -"],"part":{"year":"2025","extent":"8","text":"(2025), Artikel-ID gkaf1081, Seite 1-8","pages":"1-8"},"origin":[{"dateIssuedKey":"1974","publisher":"Oxford Univ. Press","publisherPlace":"Oxford","dateIssuedDisp":"1974-"}],"id":{"issn":["1362-4962"],"eki":["26813250X"],"zdb":["1472175-2"]}}],"origin":[{"dateIssuedDisp":"29 October 2025","dateIssuedKey":"2025"}],"id":{"doi":["10.1093/nar/gkaf1081"],"eki":["1945019271"]},"person":[{"family":"Rosado-Tristani","given":"Diego","display":"Rosado-Tristani, Diego","roleDisplay":"VerfasserIn","role":"aut"},{"family":"Albu","given":"Mihai","roleDisplay":"VerfasserIn","role":"aut","display":"Albu, Mihai"},{"display":"Chen, Xiaoting","roleDisplay":"VerfasserIn","role":"aut","family":"Chen","given":"Xiaoting"},{"family":"Sasse","given":"Alexander","display":"Sasse, Alexander","role":"aut","roleDisplay":"VerfasserIn"},{"family":"Laverty","given":"Kaitlin U","display":"Laverty, Kaitlin U","role":"aut","roleDisplay":"VerfasserIn"},{"roleDisplay":"VerfasserIn","role":"aut","display":"Ray, Debashish","family":"Ray","given":"Debashish"},{"family":"Tam","given":"Cyrus L","display":"Tam, Cyrus L","role":"aut","roleDisplay":"VerfasserIn"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Ernst, Kevin","given":"Kevin","family":"Ernst"},{"given":"Lucinda P","family":"Lawson","roleDisplay":"VerfasserIn","role":"aut","display":"Lawson, Lucinda P"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Morris, Quaid D","given":"Quaid D","family":"Morris"},{"display":"Hughes, Timothy R","role":"aut","roleDisplay":"VerfasserIn","given":"Timothy R","family":"Hughes"},{"roleDisplay":"VerfasserIn","role":"aut","display":"Weirauch, Matthew T","family":"Weirauch","given":"Matthew T"}],"note":["Veröffentlicht: 29. Oktober 2025","Gesehen am 08.12.2025"],"recId":"1945019271","language":["eng"],"physDesc":[{"extent":"8 S.","noteIll":"Illustrationen"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"name":{"displayForm":["Diego A. Rosado-Tristani, Mihai Albu, Xiaoting Chen, Alexander Sasse, Kaitlin U. Laverty, Debashish Ray, Cyrus L. Tam, Kevin Ernst, Lucinda P. Lawson, Quaid D. Morris, Timothy R. Hughes, Matthew T. Weirauch"]},"title":[{"title_sort":"CisBP-RNA","title":"CisBP-RNA","subtitle":"a web resource for eukaryotic RNA-binding proteins and their motifs"}]} | ||
| SRT | |a ROSADOTRISCISBPRNA2920 | ||