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Prevalence and risk factors of Epiretinal membranes in a Chinese population: the Kailuan Eye study

To investigate the prevalence of epiretinal membranes (ERMs) and their risk factors in a Chinese population. The community-based Kailuan Eye Study included 14,440 participants (9835 male, 4605 female) with a mean age of 54.0 ± 13.3 years (range, 20-110 years). They underwent a systemic and ophtha...

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Main Authors: Zhu, Xiao Bo (Author) , Yang, Mo Chi (Author) , Wang, Ya Xing (Author) , Qian, Wang (Author) , Yan, Yan Ni (Author) , Yang, Jing Yan (Author) , Wu, Shou Ling (Author) , Chen, Shuo Hua (Author) , Dong, Li (Author) , Wei, Wen Bin (Author) , Jonas, Jost B. (Author)
Format: Article (Journal)
Language:English
Published: September 2020
In: Investigative ophthalmology & visual science
Year: 2020, Volume: 61, Issue: 11, Pages: 1-6
ISSN:1552-5783
DOI:10.1167/iovs.61.11.37
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1167/iovs.61.11.37
Verlag, kostenfrei, Volltext: https://iovs.arvojournals.org/article.aspx?articleid=2770820
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Author Notes:Xiao Bo Zhu, Mo Chi Yang, Ya Xing Wang, Wang Qian, Yan Ni Yan, Jing Yan Yang, Shou Ling Wu, Shuo Hua Chen, Li Dong, Wen Bin Wei, and Jost B. Jonas
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Summary:To investigate the prevalence of epiretinal membranes (ERMs) and their risk factors in a Chinese population. The community-based Kailuan Eye Study included 14,440 participants (9835 male, 4605 female) with a mean age of 54.0 ± 13.3 years (range, 20-110 years). They underwent a systemic and ophthalmologic examination. ERMs were diagnosed on fundus photographs. Retinal photographs assessable for the presence of ERMs were available for 13,295 (92.0%) individuals (9094 male) with a mean age of 53.6 ± 13.3 years (range, 20-110 years). ERMs were found in 1013 participants (1489 eyes) with a prevalence of 7.6% (95% confidence interval [CI], 7.1%-8.1%). Secondary ERMs caused by intraocular reasons were found 46 (4.5%) individuals (69 [4.6%] eyes). A higher prevalence of any ERMs (and of primary ERMs) was associated with older age (odds ratio [OR]: 1.08; 95% CI:1.07-1.10), higher body mass index (OR: 1.05; 95% CI: 1.00-1.11), higher prevalence of smoking (OR:1.43; 95% CI: 1.01-2.03), higher serum concentration of glucose (OR: 1.08; 95% CI: 1.04-1.13), and lower serum concentration of uric acid (OR: 0.99; 95% CI: 0.99-1.00). Visual acuity was significantly (P = 0.002) lower in eyes with premacular fibroses than in eyes with cellophane macular reflexes. In our cross-sectional community-based study, the prevalence of all ERMs was 7.6%. Among the group of participants with ERMs, secondary ERMs caused by intraocular reasons were detected in 46 (4.5%) individuals (69 [4.6%] eyes). A higher prevalence of any ERM and of primary ERMs was associated with older age, higher body mass index, higher prevalence of smoking, a higher serum concentration of glucose, and a lower serum concentration of uric acid.
Item Description:Gesehen am 09.12.2025
Physical Description:Online Resource
ISSN:1552-5783
DOI:10.1167/iovs.61.11.37

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