Immunohistochemical analysis of YB-1 expression in the developing mouse eye
Cold shock domain (CSD) proteins, such as YB-1, play a crucial role in the regulation of transcription, mRNA stability, and translation. Consequently, YB-1 is implicated in processes such as cell differentiation, oncogenesis and oxidative stress response. The development of the eye is a complex proc...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
3 November 2025
|
| In: |
European journal of histochemistry
Year: 2025, Jahrgang: 69, Heft: 4, Pages: [1-8] |
| ISSN: | 2038-8306 |
| DOI: | 10.4081/ejh.2025.4244 |
| Online-Zugang: | Resolving-System, kostenfrei: https://dx.doi.org/ 10.4081/ejh.2025.4244 Verlag, kostenfrei, Volltext: https://doi.org/10.4081/ejh.2025.4244 Verlag, kostenfrei, Volltext: https://www.ejh.it/ejh/article/view/4244 
|
| Verfasserangaben: | Alexander Forian Nass, Hella Wolf, Saadettin Sel, Thomas Kalinski, Norbert Nass |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1945158484 | ||
| 003 | DE-627 | ||
| 005 | 20260219123236.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 251209s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.4081/ejh.2025.4244 |2 doi | |
| 035 | |a (DE-627)1945158484 | ||
| 035 | |a (DE-599)KXP1945158484 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Nass, Alexander Florian |e VerfasserIn |0 (DE-588)1390730212 |0 (DE-627)1961783835 |4 aut | |
| 245 | 1 | 0 | |a Immunohistochemical analysis of YB-1 expression in the developing mouse eye |c Alexander Forian Nass, Hella Wolf, Saadettin Sel, Thomas Kalinski, Norbert Nass |
| 264 | 1 | |c 3 November 2025 | |
| 300 | |a 8 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 19.02.2026 | ||
| 520 | |a Cold shock domain (CSD) proteins, such as YB-1, play a crucial role in the regulation of transcription, mRNA stability, and translation. Consequently, YB-1 is implicated in processes such as cell differentiation, oncogenesis and oxidative stress response. The development of the eye is a complex process that involves the differentiation of numerous highly specialized cell types. We hypothesized that YB-1 is involved in both eye development and stress defense mechanisms. As an initial step, we investigated the expression of YB-1 during the embryology of the mouse eye. YB-1 mRNA could be detected by RT-PCR and sequencing the PCR product in retinal tissue of adult mice. To elucidate the expression pattern of YB-1 protein during mouse eye development, we analyzed its expression in the developing mouse eye at embryonic day 13 (E13), E15, E18 and postnatal day 14 (P14) using immunohistochemistry. Expression of the YB-1 protein was detected in all retinal cells, as well as in the corneal and lens epithelial cells, throughout all stages of eye development examined. These findings suggest that YB-1 could have a significant role in the eye, potentially related to development and differentiation. | ||
| 650 | 4 | |a cornea | |
| 650 | 4 | |a development | |
| 650 | 4 | |a eye | |
| 650 | 4 | |a immunohistochemistry | |
| 650 | 4 | |a retina | |
| 650 | 4 | |a YB-1 | |
| 700 | 1 | |a Wolf, Hella |e VerfasserIn |4 aut | |
| 700 | 1 | |a Sel, Saadettin |d 1968- |e VerfasserIn |0 (DE-588)122466926 |0 (DE-627)081961472 |0 (DE-576)293284474 |4 aut | |
| 700 | 1 | |a Kalinski, Thomas |d 1973- |e VerfasserIn |0 (DE-588)121468062 |0 (DE-627)081327595 |0 (DE-576)292726813 |4 aut | |
| 700 | 1 | |a Naß, Norbert |e VerfasserIn |0 (DE-588)1163325562 |0 (DE-627)1027623921 |0 (DE-576)507917235 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t European journal of histochemistry |d Pavia : PAGEPress, 2000 |g 69(2025), 4, Artikel-ID 4244, Seite [1-8] |h Online-Ressource |w (DE-627)661263290 |w (DE-600)2610811-2 |w (DE-576)345581296 |x 2038-8306 |7 nnas |a Immunohistochemical analysis of YB-1 expression in the developing mouse eye |
| 773 | 1 | 8 | |g volume:69 |g year:2025 |g number:4 |g elocationid:4244 |g pages:[1-8] |g extent:8 |a Immunohistochemical analysis of YB-1 expression in the developing mouse eye |
| 856 | 4 | 0 | |u https://dx.doi.org/ 10.4081/ejh.2025.4244 |x Resolving-System |z kostenfrei |7 0 |
| 856 | 4 | 0 | |u https://doi.org/10.4081/ejh.2025.4244 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |7 0 |
| 856 | 4 | 0 | |u https://www.ejh.it/ejh/article/view/4244 |x Verlag |z kostenfrei |3 Volltext |7 0 |
| 951 | |a AR | ||
| 992 | |a 20260219 | ||
| 993 | |a Article | ||
| 994 | |a 2025 | ||
| 998 | |g 122466926 |a Sel, Saadettin |m 122466926:Sel, Saadettin |d 50000 |d 910000 |d 910900 |e 50000PS122466926 |e 910000PS122466926 |e 910900PS122466926 |k 0/50000/ |k 0/910000/ |k 1/910000/910900/ |p 4 | ||
| 999 | |a KXP-PPN1945158484 |e 4920263066 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"language":["eng"],"recId":"661263290","type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Immunohistochemical analysis of YB-1 expression in the developing mouse eyeEuropean journal of histochemistry","note":["Gesehen am 12.10.20"],"title":[{"title_sort":"European journal of histochemistry","title":"European journal of histochemistry"}],"pubHistory":["Nachgewiesen 44.2000 -"],"origin":[{"dateIssuedDisp":"2000-","publisher":"PAGEPress","dateIssuedKey":"2000","publisherPlace":"Pavia"}],"id":{"zdb":["2610811-2"],"eki":["661263290"],"issn":["2038-8306"]},"part":{"issue":"4","extent":"8","pages":"[1-8]","volume":"69","year":"2025","text":"69(2025), 4, Artikel-ID 4244, Seite [1-8]"}}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"recId":"1945158484","language":["eng"],"name":{"displayForm":["Alexander Forian Nass, Hella Wolf, Saadettin Sel, Thomas Kalinski, Norbert Nass"]},"physDesc":[{"extent":"8 S."}],"id":{"eki":["1945158484"],"doi":["10.4081/ejh.2025.4244"]},"origin":[{"dateIssuedKey":"2025","dateIssuedDisp":"3 November 2025"}],"title":[{"title":"Immunohistochemical analysis of YB-1 expression in the developing mouse eye","title_sort":"Immunohistochemical analysis of YB-1 expression in the developing mouse eye"}],"person":[{"display":"Nass, Alexander Florian","given":"Alexander Florian","role":"aut","family":"Nass"},{"given":"Hella","role":"aut","family":"Wolf","display":"Wolf, Hella"},{"display":"Sel, Saadettin","role":"aut","given":"Saadettin","family":"Sel"},{"given":"Thomas","role":"aut","family":"Kalinski","display":"Kalinski, Thomas"},{"display":"Naß, Norbert","role":"aut","given":"Norbert","family":"Naß"}],"note":["Gesehen am 19.02.2026"]} | ||
| SRT | |a NASSALEXANIMMUNOHIST3202 | ||