Chemical tools to characterize the coordination chemistry of radionuclides for radiopharmaceutical applications
During the past decade, the advancement and approval of novel radiopharmaceuticals for clinical application has led to a resurgence of the field of radiochemistry and specifically the coordination chemistry of radionuclides. In addition to well established radionuclides, short-lived radioisotopes of...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
28 October 2025
|
| In: |
Chemical reviews
Year: 2025, Pages: 1-39 |
| ISSN: | 1520-6890 |
| DOI: | 10.1021/acs.chemrev.5c00641 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1021/acs.chemrev.5c00641
|
| Verfasserangaben: | Eszter Boros, Peter Comba, Jonathan W. Engle, Charlene Harriswangler, Suzanne E. Lapi, Jason S. Lewis, Simona Mastroianni, Liviu M. Mirica, Carlos Platas-Iglesias, Caterina F. Ramogida, Raphaël Tripier, and Marianna Tosato |
MARC
| LEADER | 00000naa a22000002c 4500 | ||
|---|---|---|---|
| 001 | 194605433X | ||
| 003 | DE-627 | ||
| 005 | 20251215120103.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 251215s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1021/acs.chemrev.5c00641 |2 doi | |
| 035 | |a (DE-627)194605433X | ||
| 035 | |a (DE-599)KXP194605433X | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 30 |2 sdnb | ||
| 100 | 1 | |a Boros, Eszter |e VerfasserIn |0 (DE-588)138437986X |0 (DE-627)1946054968 |4 aut | |
| 245 | 1 | 0 | |a Chemical tools to characterize the coordination chemistry of radionuclides for radiopharmaceutical applications |c Eszter Boros, Peter Comba, Jonathan W. Engle, Charlene Harriswangler, Suzanne E. Lapi, Jason S. Lewis, Simona Mastroianni, Liviu M. Mirica, Carlos Platas-Iglesias, Caterina F. Ramogida, Raphaël Tripier, and Marianna Tosato |
| 264 | 1 | |c 28 October 2025 | |
| 300 | |b Illustrationen | ||
| 300 | |a 39 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Online veröffentlicht: 28. Oktober 2025 | ||
| 500 | |a Gesehen am 15.12.2025 | ||
| 520 | |a During the past decade, the advancement and approval of novel radiopharmaceuticals for clinical application has led to a resurgence of the field of radiochemistry and specifically the coordination chemistry of radionuclides. In addition to well established radionuclides, short-lived radioisotopes of other elements are becoming accessible using new isotope production methods, necessitating the development of coordination chemistry compatible with the aqueous chemistry of such elements under tracer level conditions. As radiochemistry with radioactive metal ions relevant for radiopharmaceuticals is conducted at the nano- to picomole scale, conventional chemical characterization techniques can generally not be applied. Therefore, careful consideration and interfacing of tracer-level compatible techniques and macroscopic characterization methods is required. This Review provides an in-depth survey of common, contemporary characterization strategies for the coordination chemistry of radionuclides, including case studies to demonstrate context and relevance for the prospective development of clinically translatable radiopharmaceuticals. | ||
| 700 | 1 | |a Comba, Peter |d 1953- |e VerfasserIn |0 (DE-588)122976843 |0 (DE-627)082271712 |0 (DE-576)160608988 |4 aut | |
| 700 | 1 | |a Engle, Jonathan W. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Harriswangler, Charlene |e VerfasserIn |4 aut | |
| 700 | 1 | |a Lapi, Suzanne E. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Lewis, Jason S. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Mastroianni, Simona |e VerfasserIn |4 aut | |
| 700 | 1 | |a Mirica, Liviu M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Platas-Iglesias, Carlos |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ramogida, Caterina F. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tripier, Raphaël |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tosato, Marianna |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Chemical reviews |d Washington, DC : ACS Publ., 1924 |g (2025), Seite 1-39 |h Online-Ressource |w (DE-627)320429717 |w (DE-600)2003609-7 |w (DE-576)090884132 |x 1520-6890 |7 nnas |a Chemical tools to characterize the coordination chemistry of radionuclides for radiopharmaceutical applications |
| 773 | 1 | 8 | |g year:2025 |g pages:1-39 |g extent:39 |a Chemical tools to characterize the coordination chemistry of radionuclides for radiopharmaceutical applications |
| 856 | 4 | 0 | |u https://doi.org/10.1021/acs.chemrev.5c00641 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |7 0 |
| 951 | |a AR | ||
| 992 | |a 20251215 | ||
| 993 | |a Article | ||
| 994 | |a 2025 | ||
| 998 | |g 122976843 |a Comba, Peter |m 122976843:Comba, Peter |d 120000 |d 120200 |e 120000PC122976843 |e 120200PC122976843 |k 0/120000/ |k 1/120000/120200/ |p 2 | ||
| 999 | |a KXP-PPN194605433X |e 4828054596 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"name":{"displayForm":["Eszter Boros, Peter Comba, Jonathan W. Engle, Charlene Harriswangler, Suzanne E. Lapi, Jason S. Lewis, Simona Mastroianni, Liviu M. Mirica, Carlos Platas-Iglesias, Caterina F. Ramogida, Raphaël Tripier, and Marianna Tosato"]},"note":["Online veröffentlicht: 28. Oktober 2025","Gesehen am 15.12.2025"],"recId":"194605433X","person":[{"family":"Boros","display":"Boros, Eszter","given":"Eszter","role":"aut"},{"family":"Comba","display":"Comba, Peter","given":"Peter","role":"aut"},{"given":"Jonathan W.","display":"Engle, Jonathan W.","family":"Engle","role":"aut"},{"role":"aut","given":"Charlene","family":"Harriswangler","display":"Harriswangler, Charlene"},{"role":"aut","family":"Lapi","display":"Lapi, Suzanne E.","given":"Suzanne E."},{"given":"Jason S.","display":"Lewis, Jason S.","family":"Lewis","role":"aut"},{"given":"Simona","display":"Mastroianni, Simona","family":"Mastroianni","role":"aut"},{"role":"aut","family":"Mirica","display":"Mirica, Liviu M.","given":"Liviu M."},{"given":"Carlos","display":"Platas-Iglesias, Carlos","family":"Platas-Iglesias","role":"aut"},{"role":"aut","family":"Ramogida","display":"Ramogida, Caterina F.","given":"Caterina F."},{"given":"Raphaël","display":"Tripier, Raphaël","family":"Tripier","role":"aut"},{"role":"aut","given":"Marianna","family":"Tosato","display":"Tosato, Marianna"}],"physDesc":[{"noteIll":"Illustrationen","extent":"39 S."}],"title":[{"title":"Chemical tools to characterize the coordination chemistry of radionuclides for radiopharmaceutical applications","title_sort":"Chemical tools to characterize the coordination chemistry of radionuclides for radiopharmaceutical applications"}],"relHost":[{"origin":[{"dateIssuedKey":"1924","publisher":"ACS Publ.","dateIssuedDisp":"1924-","publisherPlace":"Washington, DC"}],"titleAlt":[{"title":"CR"}],"title":[{"title":"Chemical reviews","subtitle":"CR","title_sort":"Chemical reviews"}],"physDesc":[{"extent":"Online-Ressource"}],"part":{"text":"(2025), Seite 1-39","pages":"1-39","extent":"39","year":"2025"},"disp":"Chemical tools to characterize the coordination chemistry of radionuclides for radiopharmaceutical applicationsChemical reviews","name":{"displayForm":["American Chemical Society"]},"pubHistory":["1.1924/25 -"],"recId":"320429717","note":["Gesehen am 27.08.2020"],"id":{"issn":["1520-6890"],"zdb":["2003609-7"],"eki":["320429717"]},"language":["eng"],"type":{"bibl":"periodical","media":"Online-Ressource"},"corporate":[{"role":"isb","display":"American Chemical Society"}]}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"id":{"doi":["10.1021/acs.chemrev.5c00641"],"eki":["194605433X"]},"language":["eng"],"origin":[{"dateIssuedDisp":"28 October 2025","dateIssuedKey":"2025"}]} | ||
| SRT | |a BOROSESZTECHEMICALTO2820 | ||