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Multiple brain metastases: resection with IORT versus adjuvant radiotherapy and concurrent irradiation of unresected lesions

Treatment of multiple brain metastases (BM) often involves surgical resection of one lesion combined with stereotactic radiotherapy (SRT) to the resection cavity and unresected BM. Intraoperative radiotherapy (IORT) is an emerging alternative for treating the resection cavity, potentially dosimetric...

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Bibliographic Details
Main Authors: Wieger, Gero (Author) , Godó Jiménez, Àlex (Author) , Brehmer, Stefanie (Author) , Etminan, Nima (Author) , Stieler, Florian (Author) , Giordano, Frank Anton (Author) , Ruder, Arne Mathias (Author)
Format: Article (Journal)
Language:English
Published: 21 October 2025
In: Radiation oncology
Year: 2025, Volume: 20, Issue: 1, Pages: 1-8
ISSN:1748-717X
DOI:10.1186/s13014-025-02736-2
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13014-025-02736-2
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1186/s13014-025-02736-2
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Author Notes:Gero Wieger, Àlex Godó Jiménez, Stefanie Brehmer, Nima Etminan, Florian Stieler, Frank A. Giordano and Arne Mathias Ruder
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Summary:Treatment of multiple brain metastases (BM) often involves surgical resection of one lesion combined with stereotactic radiotherapy (SRT) to the resection cavity and unresected BM. Intraoperative radiotherapy (IORT) is an emerging alternative for treating the resection cavity, potentially dosimetric benefits. This study aimed to compare the dosimetry of treating the resection cavity with IORT versus adjuvant SRT when combined with SRT for additional unresected BM.
Item Description:Gesehen am 16.12.2025
Physical Description:Online Resource
ISSN:1748-717X
DOI:10.1186/s13014-025-02736-2

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